Identification of small-molecule scaffolds for P450 inhibitors

Current Protocols in Microbiology

Volumn , Issue SUPPL. 16, 2010, Pages

  Kries, Jens P ^a   Warrier, Thulasi ^b   Podust, Larissa M ^c  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CYP; High throughput screening; Mycobacterium tuberculosis; P450; Small molecule inhibitors; X ray crystallography

Indexed keywords

CYTOCHROME P450 INHIBITOR; SELENOMETHIONINE;

BINDING AFFINITY; CRYSTALLIZATION; ENZYME PURIFICATION; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; LIGAND BINDING; LIQUID CULTURE; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; MYCOBACTERIUM TUBERCULOSIS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 77949346138     PISSN: 19348525     EISSN: 19348533     Source Type: Journal    
DOI: 10.1002/9780471729259.mc1704s16     Document Type: Review

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