Wnt gene expression in human trabecular meshwork cells

Molecular Vision

Volumn 16, Issue , 2010, Pages 122-129

  Shyam, Rajalekshmy ^a,b   Shen, Xiang ^a   Yue, Beatrice Y J T ^a   Wentz Hunter, Kelly K ^b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b ROOSEVELT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; APC PROTEIN; BETA CATENIN; COMPLEMENTARY DNA; DISHEVELLED 1; DISHEVELLED 2; DISHEVELLED 3; DISHEVELLED PROTEIN; FRIZZLED 1 PROTEIN; FRIZZLED 2 PROTEIN; FRIZZLED 4 PROTEIN; FRIZZLED 5 PROTEIN; FRIZZLED 7 PROTEIN; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 7; RNA; SECRETED FRIZZLED RELATED PROTEIN 1; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT2 PROTEIN; WNT2B PROTEIN; WNT3 PROTEIN; WNT5A PROTEIN; WNT5B PROTEIN; FRIZZLED RELATED PROTEIN-1; LIGAND; PROTEIN;

ADULT; ARTICLE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; STAINING; TRABECULAR MESHWORK; WESTERN BLOTTING; CYTOLOGY; GENETICS; METABOLISM; MIDDLE AGED;

ACTINS; ADULT; BETA CATENIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; MIDDLE AGED; PROTEINS; STAINING AND LABELING; TRABECULAR MESHWORK; WNT PROTEINS;

EID: 77949317527     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Bill A. Editorial: The drainage of aqueous humor. Invest Ophthalmol 1975; 14:1-3. [PMID: 1110131]
2. Nusse R, Varmus HE. Wnt genes. Cell 1992; 69:1073-1087. [PMID: 1617723]
3. Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20:781-810. [PMID: 15473860]
4. Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005; 434:843-850. [PMID: 15829953]
5. Mosimann C, Hausmann G, Basler K. β-Catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 2009; 10:276-286. [PMID: 19305417]
6. Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14:1837-1851. [PMID: 10921899]
7. Kühl M, Sheldahl LC, Park M, Miller JR, Moon RT. The Wnt/ Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet 2000; 16:279-283. [PMID: 10858654]
8. Bovolenta P, Esteve P, Jose MR, Cisneros E, Lopez-Rios J. Beyond Wnt inhibition: new functions of secreted frizzled related proteins in development and disease. J Cell Sci 2008; 121:737-746. [PMID: 18322270]
9. Chen L, Wang K, Shao Y, Huang J, Li X, Shan J, Wu D, Zheng JJ. Structural insight into mechanisms of Wnt signaling antagonism by Dkk. J Biol Chem 2008; 283:23364-23370. [PMID: 18524778]
10. Kawano Y, Kypta R. Secreted antagonists of the Wnt signaling pathway. J Cell Sci 2003; 116:2627-2634. [PMID: 12775774]
11. Wang WH, McNatt LG, Pang IH, Millar JC, Hellberg PE, Hellberg MH, Steely HT, Rubin JS, Fingert JH, Sheffield VC, Stone EM, Clark AF. Increased expression of the Wnt antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest 2008; 118:1056-1064. [PMID: 18274669]
12. Zanon-Moreno V, Marco-Ventura P, Lleo-Perez A, Pons-Vazquez S, Garcia-Medina JJ, Vinuesa-Silva I, Moreno-Nadal MA, Pinazo-Duran MD. Oxidative stress in primary open-angle glaucoma. J Glaucoma 2008; 17:263-268. [PMID: 18552610]
13. Izzotti A, Sacca SC, Cartiglia C, De Flora S. Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients. Am J Med 2003; 114:638-646. [PMID: 12798451]
14. Sacca SC, Pascotto A, Camicione P, Capris P, Izzotti A. Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma. Arch Ophthalmol 2005; 123:458-463. [PMID: 15824217]
15. Liton PB, Gonzalez P. Stress response of the trabecular meshwork. J Glaucoma 2008; 17:378-385. [PMID: 18703948]
16. Saccà SC, Izzotti A. Oxidative stress and glaucoma: injury in the anterior segment of the eye. Prog Brain Res 2008; 173:385-407. [PMID: 18929123]
17. Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC. Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting β-catenin from T cell factor- to forkhead box O-mediated transcription. J Biol Chem 2007; 282:27298-27305. [PMID: 17623658]
18. Funato Y, Michiue T, Asashima M, Miki H. The thioredoxinrelated redox-regulating protein nucleoredoxin inhibits Wnt- β-catenin signalling through dishevelled. Nat Cell Biol 2006; 8:501-508. [PMID: 16604061]
19. Shin SY, Kim CG, Jho E-H, Rho M-S, Kim YS, Kim Y-H, Lee YH. Hydrogen peroxide negatively modulates Wnt signaling through downregulation of β-catenin. Cancer Lett 2004; 212:225-231. [PMID: 15279902]
20. Yue BY, Elvart JL. Biosynthesis of glycosaminoglycans by trabecular meshwork cells in vitro. Curr Eye Res 1987; 6:959-667. [PMID: 3311645]
21. Zhou L, Fukuchi T, Kawa JE, Higginbotham EJ, Yue BY. Loss of cell-matrix cohesiveness after phagocytosis by trabecular meshwork cells. Invest Ophthalmol Vis Sci 1995; 36:787-795. [PMID: 7706026]
22. Zhou L, Li Y, Yue BY. Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: the trabecular meshwork. J Cell Physiol 1999; 180:182-189. [PMID: 10395288]
23. Melkonyan HS, Chang WC, Shapiro JP, Mahadevappa M, Fitzpatrick PA, Kiefer MC, Tomei LD, Umansky SR. SARPs: a family of secreted apoptosis-related proteins. Proc Natl Acad Sci USA 1997; 94:13636-13641. [PMID: 9391078]
24. Katoh M. Regulation of Wnt3 and Wnt3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45. Int J Oncol 2002; 20:373-377. [PMID: 11788904]
25. Kirikoshi H, Katoh M. Expression and regulation of Wnt10B in human cancer: up-regulation of Wnt10B in MCF-7 cells by β-estradiol and down-regulation of Wnt10B in NT2 cells by retinoic acid. Int J Mol Med 2002; 10:507-511. [PMID: 12239602]
26. Katoh M. Differential regulation of Wnt2 and Wnt2B expression in human cancer. Int J Mol Med 2001; 8:657-660. [PMID: 11712082]
27. Vermeulen SJ, Bruyneel EA, van Roy FM, Mareel MM, Bracke ME. Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid. Br J Cancer 1995; 72:1447-1453. [PMID: 8519658]
28. Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL. Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue. Cancer Res 1994; 54:2615-2621. [PMID: 8168088]
29. Björklund P, Svedlund J, Olsson AK, Åkerström G, Westin G. The internally truncated LRP5 receptor presents a therapeutic target in breast cancer. PLoS One 2009; 4:e4243. [PMID: 19158955]
30. Ott M-O, Rey-Campos J, Cereghini S, Yaniv M. vHNF1 is expressed in epithelial cells of distinct embryonic origin during development and precedes HNF1 expression. Mech Dev 1991; 36:47-58. [PMID: 1685890]
31. de Iongh RU, Abud HE, Hime GR. Wnt/frizzled signaling in eye development and disease. Front Biosci 2006; 11:2442-2464. [PMID: 16720326]
32. McCartney BM, Dierick HA, Kirkpatrick C, Moline MM, Baas A, Peifer M, Bejsovec A. Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J Cell Biol 1999; 146:1303-1318. [PMID: 10491393]
33. Miller JR, Moon RT. Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev 1996; 10:2527-2539. [PMID: 8895655]
34. Kanazawa A, Tsukada S, Kamiyama M, Yanagimoto T, Nakajima M, Maeda S. Wnt5b partially inhibits canonical Wnt/β-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes. Biochem Biophys Res Commun 2005; 330:505-510. [PMID: 15796911]
35. Zhao X, Ramsey KE, Stephan DA, Russell P. Gene and protein expression changes in human trabecular meshwork cellstreated with transforming growth factor-β. Invest Ophthalmol Vis Sci 2004; 45:4023-4034. [PMID: 15505052]
36. Ille F, Atanasoski S, Falk S, Ittner LM, Märki D, Büchmann-Møller S, Wurdak H, Suter U, Taketo MM, Sommer L. Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Dev Biol 2007; 304:394-408. [PMID: 17292876]
37. Prakash N, Wolfgang W. A Wnt signal regulates stem cell fate and differentiation in vivo. Neurodegener Dis 2007; 4:333-338. [PMID: 17627138]
38. Castrop J, van Wichen D, Koomans- Bitter M, van de Wetering M, de Weger R, van Dongen J, Clevers H. The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes. Blood 1995; 86:3050-3059. [PMID: 7579399]
39. Roose J, Huls G, van Beest M, Moerer P, van der Horn K, Goldschmeding R, Logtenberg T, Clevers H. Synergy between tumor suppressor APC and the β-catenin-TCF4 target TCF1. Science 1999; 285:1923-1926. [PMID: 10489374]
40. Noble JA, White AM, Lazzeroni LC, Valdes AM, Mirel DB, Reynolds R, Grupe A, Aud D, Peltz G, Erlich HA. A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Diabetes 2003; 52:1579-1582. [PMID: 12765974]
41. 2 at physiologically relevant EGCG concentrations. Biochem Biophys Res Commun 2002; 296:584-588. [PMID: 12176021]
42. Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J 1997; 16:3797-3804. [PMID: 9233789]
43. Cowling VH, D'Cruz CM, Chodosh LA, Cole MD. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Mol Cell Biol 2007; 27:5135-5146. [PMID: 17485441]