Invasive growth: From development to metastasis

Journal of Clinical Investigation

Volumn 109, Issue 7, 2002, Pages 857-862

  Comoglio, Paolo M ^a,b   Trusolino, Livio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b CANDIOLO CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PLEXIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SEMAPHORIN; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL GROWTH; CELL INVASION; CELL PROLIFERATION; EMBRYO DEVELOPMENT; FETUS DEVELOPMENT; GENE ISOLATION; HUMAN; HUMAN CELL; METASTASIS; MORPHOGENESIS; NONHUMAN; ONCOGENE; ONCOGENE MET; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVIEW; TUMOR GROWTH;

AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; CELL MOVEMENT; CELL SURVIVAL; FISH PROTEINS; GLYCOPROTEINS; GROWTH SUBSTANCES; HEPATOCYTE GROWTH FACTOR; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; SEMAPHORIN-3A; SIGNAL TRANSDUCTION;

EID: 0036217866     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200215392     Document Type: Review

References (60)

1. Scatter factors and invasive growth
2. Interactions between scatter factors and their receptors: Hints for therapeutic applications
3. Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses
4. Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures
5. Scatter factor is a fibroblast-derived modulator of epithelial cell motility
6. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the Met receptor
7. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
8. Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland
9. Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros
10. Hepatocyte growth factor may act as a pulmotrophic factor on lung regeneration after acute lung injury
11. Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars
12. Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling
13. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
14. Hepatocyte growth factor is a coupling factor for osteoclasts and osteoblasts in vitro
15. Hepatocyte growth factor/scatter factor modulates cell motility, proliferation, and proteoglycan synthesis of chondrocytes
16. Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors
17. Hepatocyte growth factor, a versatile signal for developing neurons
18. Scatter factor/hepatocyte growth factor is essential for liver development
19. Placental defect and embryonal lethality in mice lacking hepatocyte growth factor/scatter factor
20. Macrophage stimulating protein: Purification, partial amino acid sequence, and cellular activity
21. Interaction of macrophage-stimulating protein with its receptor. Residues critical for beta chain binding and evidence for independent alpha chain binding
22. The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro
23. The proto-oncogene RON is involved in development of epithelial, bone and neuroendocrine tissues
24. Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells
25. Modulation of megakaryocytopoiesis by human macrophage-stimulating protein, the ligand for the RON receptor
26. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
27. Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET
28. RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP
29. Identification of the ron gene product as the receptor for the human macrophage stimulating protein
30. Tyrosine kinase receptor indistinguishable from the c-met protein
31. The tytosine kinase encoded by the MET protooncogene is activated by autophosphorylation
32. Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase
33. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
34. Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development
35. Motogenic and morphogenic activity of epithelial receptor tyrosine kinases
36. Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway
37. Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal-regulated kinase activation
38. Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
39. Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility
40. Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase
41. Sustained recruitment ofphospholipase c-gamma to Gab1 is required for HGF-induced branching tubulogenesis
42. Coupling Met to specific pathways results in distinct developmental outcomes
43. The semaphorin genes encode a new family of transmembrane and secreted growth cone guidance molecules
44. Signalling by semaphorin receptors: Cell guidance and beyond
45. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
46. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
47. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
48. Activating mutations for the met tyrosine kinase receptor in human cancer
49. Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists
50. Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas
51. Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer
52. Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas
53. Identification of semaphorin E gene expression in metastatic human lung adenocarcinoma cells by mRNA differential display
54. Identification of semaphorin E as a non-MDR drug resistance gene of human cancer
55. Transcription of a novel mouse semaphorin gene, M-semaH, correlates with the metastatic ability of mouse tumor cell lines
56. Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity
57. Dysregulation of Met receptor tyrosine kinase activity in invasive tumors
58. Integrins in invasive growth
59. The cadherin-carenin adhesion system in signaling and cancer
60. Semaphorins as signals for cell repulsion and invasion