Long-term fate of allogeneic neural stem cells following transplantation into injured spinal cord

Stem Cell Reviews and Reports

Volumn 6, Issue 1, 2010, Pages 121-136

  Xu, Liang ^a   Xu, Chao jin ^a   Lü, He Zuo ^a   Wang, Yan Xia ^a   Li, Ying ^a   Lu, Pei Hua ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Allogeneic transplantation; Green fluorescent protein; Immune response; Neural stem cell; Spinal cord injury

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ALLOTRANSPLANTATION; ANIMAL; ARTICLE; ASTROCYTE; BIOSYNTHESIS; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; CONVALESCENCE; DISEASE MODEL; EMBRYONIC STEM CELL; FEMALE; GENETICS; GRAFT REJECTION; IMMUNOLOGY; MOTOR ACTIVITY; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; RAT; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; STEM CELL TRANSPLANTATION; TIME; TRANSGENIC RAT; TRANSPLANTATION; WISTAR RAT;

ANIMALS; ASTROCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; FEMALE; GRAFT REJECTION; GREEN FLUORESCENT PROTEINS; MOTOR ACTIVITY; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RATS, WISTAR; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; STEM CELL TRANSPLANTATION; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS;

RATTUS; RATTUS NORVEGICUS;

EID: 77949299312     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-009-9104-y     Document Type: Article

References (49)

1. Ben-Hur, T., Idelson, M., Khaner, H., Pera, M., Reinhartz, E., Itzik, A., et al. (2004). Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats. Stem Cells, 22(7), 1246-1255.
2. Roberts, T. J., Price, J., Williams, S. C., & Modo, M. (2006). Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience, 139(4), 1187-1199.
3. Cao, Q., Xu, X. M., Devries, W. H., Enzmann, G. U., Ping, P., Tsoulfas, P., et al. (2005). Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. Journal of Neuroscience, 25, 6947-6957.
4. Hasegawa, K., Chang, Y. W., Li, H., Berlin, Y., Ikeda, O., Kane-Goldsmith, N., et al. (2005). Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury. Experimental Neurology, 193, 394-410.
5. Lepore, A. C. & Fischer, I. (2005). Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord. Experimental Neurology, 194, 230-242.
6. Popovich, P. G. & Longbrake, E. E. (2008). Can the immune system be harnessed to repair the CNS? Nature Reviews Neuroscience, 9, 481-493.
7. Rossi, F. & Cattaneo, E. (2002). Opinion: neural stem cell therapy for neurological diseases: dreams and reality. Nature Reviews Neuroscience, 3(5), 401-409.
8. Boyd, A. S., Higashi, Y., & Wood, K. J. (2005). Transplanting stem cells: potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantation. Advanced Drug Delivery Reviews, 57(13), 1944-1969.
9. Griffiths, M., Neal, J. W., & Gasque, P. (2007). Innate immunity and protective neuroinflammation: new emphasis on the role of neuroimmune regulatory proteins. International Review of Neurobiology, 82, 29-55.
10. Fleming, J. C., Norenberg, M. D., Ramsay, D. A., Dekaban, G. A., Marcillo, A. E., Saenz, A. D., et al. (2006). The cellular inflammatory response in human spinal cords after injury. Brain, 129, 3249-3269. Pt.
11. Ben-Hur, T. (2008). Immunomodulation by neural stem cells. Journal of Neurological Science, 265, 102-104.
12. Marano, J. E., Sun, D., Zama, A. M., Young, W., & Uzumcu, M. (2008). Orthotopic transplantation of neonatal GFP rat ovary as experimental model to study ovarian development and toxicology. Reproductive Toxicology, 26, 191-196.
13. Rauch, M. F., Hynes, S. R., Bertram, J., Redmond, A., Robinson, R., Williams, C., et al. (2009). Engineering angiogenesis following spinal cord injury: a coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in vessel density and formation of the blood-spinal cord barrier. European Journal of Neuroscience, 29, 132-145.
14. Yin, L., Fu, S. L., Shi, G. Y., Li, Y., Jin, J. Q., Ma, Z. W., et al. (2008). Expression and regulation of major histocompatibility complex on neural stem cells and their lineages. Stem Cells and Development, 17, 53-65.
15. Fischer, I. (2000). Candidate cells for transplantation into the injured CNS. Progress in Brain Research, 128, 253-257.
16. Rao, M. S. & Mayer-Proschel, M. (2000). Precursor cells for transplantation. Progress in Brain Research, 128, 273-292.
17. Bjorklund, A., Dunnett, S. B., Brundin, P., Stoessl, A. J., Freed, C. R., Breeze, R. E., et al. (2003). Neural transplantation for the treatment of Parkinson's disease. Lancet Neurology, 2(7), 437-445.
18. Cummings, B. J., Uchida, N., Tamaki, S. J., Salazar, D. L., Hooshmand, M., Summers, R., et al. (2005). Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proceedings of the National Academy of Sciences of the United States of America, 102(39), 14069-14074.
19. Muraoka, K., Shingo, T., Yasuhara, T., Kameda, M., Yuan, W., Hayase, H., et al. (2006). The high integration and differentiation potential of autologous neural stem cell transplantation compared with allogeneic transplantation in adult rat hippocampus. Experimental Neurology, 199(2), 311-327.
20. Tarasenko, Y. I., Gao, J., Nie, L., Johnson, K. M., Grady, J. J., Hulsebosch, C. E., et al. (2007). Human fetal neural stem cells grafted into contusion-injured rat spinal cords improve behavior. Journal of Neuroscience Research, 85(1), 47-57.
21. Guzman, R., Uchida, N., Bliss, T. M., He, D., Christopherson, K. K., Stellwagen, D., et al. (2007). Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proceedings of the National Academy of Sciences USA, 104(24), 10211-10216.
22. Zhu, J., Zhou, L., & XingWu, F. (2006). Tracking neural stem cells in patients with brain trauma. New England Journal of Medicine, 355(22), 2376-2378.
23. Kim, D. E., Tsuji, K., Kim, Y. R., Mueller, F. J., Eom, H. S., Snyder, E. Y., et al. (2006). Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging. Radiology, 241(3), 822-830.
24. Lepore, A. C., Neuhuber, B., Connors, T. M., Han, S. S., Liu, Y., Daniels, M. P., et al. (2006). Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience, 142(1), 287-304.
25. Karimi-Abdolrezaee, S., Eftekharpour, E., Wang, J., Morshead, C. M., & Fehlings, M. G. (2006). Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. Journal of Neuroscience, 26, 3377-3389.
26. Syed, Y. A., Baer, A. S., Lubec, G., Hoeger, H., Widhalm, G., & Kotter, M. R. (2008). Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins. Neurosurgical Focus, 24(3-4), E5.
27. Wang, F. & Zhu, Y. (2008). The interaction of Nogo-66 receptor with Nogo-p4 inhibits the neuronal differentiation of neural stem cells. Neuroscience, 151(1), 74-81.
28. Stirling, D. P., Khodarahmi, K., Liu, J., McPhail, L. T., McBride, C. B., Steeves, J. D., et al. (2004). Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. Journal of Neuroscience, 24(9), 2182-2190.
29. Ikegami, T., Nakamura, M., Yamane, J., Katoh, H., Okada, S., Iwanami, A., et al. (2005). Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. European Journal of Neuroscience, 22(12), 3036-3046.
30. Lee, S. T., Park, J. E., Lee, K., Kang, L., Chu, K., Kim, S. U., et al. (2006). Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease. Journal of Neuroscience Methods, 152, 250-254.
31. Belmadani, A., Tran, P. B., Ren, D., & Miller, R. J. (2006). Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. Journal of Neuroscience, 26, 3182-3191.
32. Guzman, R., Bliss, T., De Los Angeles, A., Moseley, M., & Palmer, T. (2008). Steinberg G. Neural progenitor cells transplanted into the uninjured brain undergo targeted migration after stroke onset. Journal of Neuroscience Research, 86, 873-882.
33. Kimura, A., Ohmori, T., Ohkawa, R., Madoiwa, S., Mimuro, J., Murakami, T., et al. (2007). Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury. Stem Cells, 25, 115-124.
34. Hori, J., Ng, T. F., Shatos, M., Klassen, H., Streilein, J. W., & Young, M. J. (2003). Neural progenitor cells lack immunogenicity and resist destruction as allografts. Stem Cells, 21, 405-416.
35. Galea, I., Bechmann, I., & Perry, V. H. (2007). What is immune privilege (not)? Trends in Immunology, 28(1), 12-18.
36. Niederkorn, J. Y. (2006). See no evil, hear no evil, do no evil: the lessons of immune privilege. Nature Immunology, 7, 354-359.
37. Jiang, L. Q., Jorquera, M., Streilein, J. W., & Ishioka, M. (1995). Unconventional rejection of neural retinal allografts implanted into the immunologically privileged site of the eye. Transplantation, 59(8), 1201-1207.
38. Horner, P. J., Popovich, P. G., Mullin, B. B., & Stokes, B. T. (1996). A quantitative spatial analysis of the blood-spinal cord barrier. II. Permeability after intraspinal fetal transplantation. Experimental Neurology, 142, 226-243.
39. Popovich, P. G., Horner, P. J., Mullin, B. B., & Stokes, B. T. (1996). A quantitative spatial analysis of the blood-spinal cord barrier. I. Permeability changes after experimental spinal contusion injury. Experimental Neurology, 142, 258-275.
40. Whetstone, W. D., Hsu, J. Y., Eisenberg, M., Werb, Z., & Noble-Haeusslein, L. J. (2003). Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. Journal of Neuroscience Research, 74(2), 227-239.
41. Dai, Y., Lv, T., Wang, K., Huang, Y., Li, D., & Liu, J. (2008). Detection of acute renal allograft rejection by analysis of renal tissue proteomics in rat models of renal transplantation. Saudi Journal of Kidney Diseases and Transplantation, 19, 952-959.
42. Rokahr, K. L., Sharland, A. F., Sun, J., Wang, C., Sheil, A. G., Yan, Y., et al. (1998). Paradoxical early immune activation during acceptance of liver allografts compared with rejection of skin grafts in a rat model of transplantation. Immunology, 95, 257-263.
43. Yang, J., Ahn, C., Jung, H. K., Kim, E. K., Kim, J. Y., Kim, Y. S., et al. (2003). The expression patterns of CD44 and CD45RB on peripheral blood T lymphocytes in the rejection of allogeneic murine skin transplantation. Transplant Immunology, 11, 197-206.
44. Webber, D. J., Bradbury, E. J., McMahon, S. B., & Minger, S. L. (2007). Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord. Regenerative Medicine, 2(6), 929-945.
45. Llado, J., Haenggeli, C., Maragakis, N. J., Snyder, E. Y., & Rothstein, J. D. (2004). Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors. Molecular and Cellular Neurosciences, 27, 322-331.
46. Lu, P., Jones, L. L., Snyder, E. Y., & Tuszynski, M. H. (2003). Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Experimental Neurology, 181, 115-129.
47. Parr, A. M., Kulbatski, I., Zahir, T., Wang, X., Yue, C., Keating, A., et al. (2008). Transplanted adult spinal cord-derived neural stem/progenitor cells promote early functional recovery after rat spinal cord injury. Neuroscience, 155, 760-770.
48. Ponomarev, E. D., Maresz, K., Tan, Y., & Dittel, B. N. (2007). CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. Journal of Neuroscience, 27, 10714-10721.
49. Wang, X., Fu, S., Wang, Y., Yu, P., Hu, J., Gu, W., et al. (2007). Interleukin-1beta mediates proliferation and differentiation of multipotent neural precursor cells through the activation of SAPK/JNK pathway. Molecular and Cellular Neurosciences, 36, 343-354.