Construction of a recombinant adenovirus vector expressing IL-18BP/IL-4 fusion gene and the anti-inflammatory effect induced by this gene on lipopolysaccharide-stimulated synovial fibroblasts

Inflammation Research

Volumn 59, Issue 2, 2010, Pages 97-104

  Yao, Hang Ping ^a   Qian, Yun ^b   Shao, Xue Ting ^a   Xu, Zhe Rong ^b   Cheng, Lin Fang ^a   Feng, Lei ^a   Wu, Nan Ping ^a   Yang, Yun Mei ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Anti inflammation; Fusion gene; Interleukin 18BP; Interleukin 4; Synovial fibroblasts

Indexed keywords

ADENOVIRUS VECTOR; CYCLOOXYGENASE 2; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN P50; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FUSION GENE; GENE EXPRESSION; GENE EXPRESSION SYSTEM; GENE REPRESSION; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SUPERNATANT; SYNOVIOCYTE; VIRUS RECOMBINANT; WESTERN BLOTTING;

ADENOVIRIDAE; CELL LINE; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; FIBROBLASTS; GENETIC VECTORS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLASMIDS; RECOMBINANT FUSION PROTEINS; SYNOVIAL MEMBRANE;

EID: 77949268925     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-009-0072-0     Document Type: Article

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