Polymorphisms in the bovine leptin gene associated with perinatal mortality in Holstein-Friesian heifers

Journal of Dairy Science

Volumn 93, Issue 1, 2010, Pages 340-347

  Brickell, J S ^a   Pollott, G E ^a   Clempson, A M ^a   Otter, N ^b   Wathes, D C ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Heifer; Leptin gene; Perinatal mortality

Indexed keywords

LEPTIN;

ANIMAL; ARTICLE; CATTLE; FEMALE; GENE FREQUENCY; GENETICS; GENOTYPE; PERINATAL MORTALITY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

ANIMALS; CATTLE; FEMALE; GENE FREQUENCY; GENOTYPE; LEPTIN; LINEAR MODELS; PERINATAL MORTALITY; POLYMORPHISM, SINGLE NUCLEOTIDE;

BOVINAE; FRIESIA;

EID: 77749324901     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2009-2457     Document Type: Article

References (56)

1. Ashworth C.J., Hoggard N., Thomas L., Mercer J.G., Wallace J.M., Lea R.G. Placental leptin. Rev. Reprod. 2000, 5:18-24.
2. Bajoria R., Sooranna S.R., Ward B.S., Chatterjee R. Prospective function of placental leptin at maternal-fetal interface. Placenta 2002, 23:103-115.
3. Banos G., Woolliams J.A., Woodward B.W., Forbes A.B., Coffey M.P. Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows. J. Dairy Sci. 2008, 91:3190-3200.
4. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
5. Bergen H.T., Cherlet T.C., Manuel P., Scott J.E. Identification of leptin receptors in lung and isolated fetal type II cells. Am. J. Respir. Cell Mol. Biol. 2002, 27:71-77.
6. Berglund B., Steinbock L., Elvander M. Causes of stillbirth and time of death in Swedish Holstein calves examined post mortem. Acta Vet. Scand. 2003, 44:111-120.
7. Block S.S., Butler W.R., Ehrhardt R.A., Bell A.W., Van Amburgh M.E., Boisclair Y.R. Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance. J. Endocrinol. 2001, 171:339-348.
8. Brickell J.S., McGowan M.M., Pfeiffer D.U., Wathes D.C. Mortality in Holstein-Friesian calves and replacement heifers in relation to body weight and IGF-I concentration on 19 farms in England. Animal 2009, 3:1175-1182.
9. Buchanan F.C., Fitzsimmons C.J., Van Kessel A.G., Thue T.D., Winkelman-Sim D.C., Schmutz S.M. Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels. Genet. Sel. Evol. 2002, 34:105-116.
10. Chebel R.C., Susca F., Santos J.E. Leptin genotype is associated with lactation performance and health of Holstein cows. J. Dairy Sci. 2008, 91:2893-2900.
11. Coffey M.P., Hickey J., Brotherstone S. Genetic aspects of growth of Holstein-Friesian dairy cows from birth to maturity. J. Dairy Sci. 2006, 89:322-329.
12. Ehrhardt R.A., Slepetis R.M., Bell A.W., Boisclair Y.R. Maternal leptin is elevated during pregnancy in sheep. Domest. Anim. Endocrinol. 2001, 21:85-96.
13. Forhead A.J., Fowden A.L. The hungry fetus? The role of leptin as a nutritional signal before birth. J. Physiol. 2009, 587:1145-1152.
14. Fowden A.L., Forhead A.J., Coan P.M., Burton G.J. The placenta and intrauterine programming. J. Neuroendocrinol. 2008, 20:439-450.
15. Gilmour A.R., Gogel B.J., Cullis B.R., Thomson R. ASReml User Guide 2006, Release 2.0. VSN International Ltd, Hemel Hempstead, UK.
16. Grisaru-Granovsky S., Samueloff A., Elstein D. The role of leptin in fetal growth: A short review from conception to delivery. Eur. J. Obstet. Gynecol. Reprod. Biol. 2008, 136:146-150.
17. Hansen M., Lund M.S., Pedersen J., Christensen L.G. Gestation length in Danish Holsteins has weak genetic associations with stillbirth, calving difficulty, and calf size. Livest. Prod. Sci. 2004, 91:23-33.
18. Harbers A., Sergen L., de Jong G. Genetic parameters for stillbirth in the Netherlands. Interbull Bull. 2000, 25:117-122.
19. Henson M.C., Castracane V.D. Leptin in pregnancy. Biol. Reprod. 2000, 63:1219-1228.
20. Henson M.C., Swan K.F., Edwards D.E., Hoyle G.W., Purcell J., Castracane V.D. Leptin receptor expression in fetal lung increases in late gestation in the baboon: A model for human pregnancy. Reproduction 2004, 127:87-94.
21. Hoggard N., Crabtree J., Allstaff S., Abramovich D.R., Haggarty P. Leptin secretion to both the maternal and fetal circulation in the ex vivo perfused human term placenta. Placenta 2001, 22:347-352.
22. Ingvartsen K.L., Boisclair Y.R. Leptin and the regulation of food intake, energy homeostasis and immunity with special focus on periparturient ruminants. Domest. Anim. Endocrinol. 2001, 21:215-250.
23. Jamrozik J., Fatehi J., Kistemaker G.J., Schaeffer L.R. Estimates of genetic parameters for Canadian Holstein female reproduction traits. J. Dairy Sci. 2005, 88:2199-2208.
24. Johanson J.M., Berger P.J. Birth weight as a predictor of calving ease and perinatal mortality in Holstein cattle. J. Dairy Sci. 2003, 86:3745-3755.
25. Kirwin S.M., Bhandari V., Dimatteo D., Barone C., Johnson L., Paul S., Spitzer A.R., Chander A., Hassink S.G., Funanage V.L. Leptin enhances lung maturity in the fetal rat. Pediatr. Res. 2006, 60:200-204.
26. Kornmatitsuk B., Dahl E., Ropstad E., Beckers J.E., Gustafsson H., Kindahl H. Endocrine profiles, haematology and pregnancy outcomes of late pregnant Holstein dairy heifers sired by bulls giving a high or low incidence of stillbirth. Acta Vet. Scand. 2004, 45:47-68.
27. Liefers S.C., te Pas M.F., Veerkamp R.F., Chilliard Y., Delavaud C., Gerritsen R., van der Lende T. Association of leptin gene polymorphisms with serum leptin concentration in dairy cows. Mamm. Genome 2003, 14:657-663.
28. Lombard J.E., Garry F.B., Tomlinson S.M., Garber L.P. Impacts of dystocia on health and survival of dairy calves. J. Dairy Sci. 2007, 90:1751-1760.
29. Lusk J.L. Association of single nucleotide polymorphisms in the leptin gene with body weight and backfat growth curve parameters for beef cattle. J. Anim. Sci. 2007, 85:1865-1872.
30. Masuzaki H., Ogawa Y., Sagawa N., Hosoda K., Matsumoto T., Mise H., Nishimura H., Yoshimasa Y., Tanaka I., Mori T., Nakao K. Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans. Nat. Med. 1997, 3:1029-1033.
31. McCrabb G.J., Egan A.R., Hosking B.J. Maternal undernutrition during mid-pregnancy in sheep. Placental size and its relationship to calcium transfer during late pregnancy. Br. J. Nutr. 1991, 65:157-168.
32. Mee J.F., Berry D.P., Cronie A.R. Prevalence of, and risk factors associated with, perinatal calf mortality in pasture-based Holstein-Friesian cows. Animal 2008, 2:613-620.
33. Meijering A. Dystocia and stillbirth in cattle-A review of causes, relations and implications. Livest. Prod. Sci. 1984, 11:143-177.
34. Meller M., Qiu C., Vadachkoria S., Abetew D.F., Luthy D.A., Williams M.A. Changes in placental adipocytokine gene expression associated with gestational diabetes mellitus. Physiol. Res. 2006, 55:501-512.
35. Meyer C.L., Berger P.J., Koehler K.J., Thompson J.R., Sattler C.G. Phenotypic trends in incidence of stillbirth for Holsteins in the United States. J. Dairy Sci. 2001, 84:515-523.
36. Nishizawa H., Pryor-Koishi K., Kato T., Kowa H., Kurahashi H., Udagawa Y. Microarray analysis of differentially expressed fetal genes in placental tissue derived from early and late onset severe pre-eclampsia. Placenta 2007, 28:487-497.
37. Nkrumah J.D., Li C., Yu J., Hansen C., Keisler D.H., Moore S.S. Polymorphisms in the bovine leptin promoter associated with serum leptin concentration, growth, feed intake, feeding behavior, and measures of carcass merit. J. Anim. Sci. 2005, 83:20-28.
38. O'Donnell C.P., Tankersley C.G., Polotsky V.P., Schwartz A.R., Smith P.L. Leptin, obesity, and respiratory function. Respir. Physiol. 2000, 119:163-170.
39. Ong K.K., Preece M.A., Emmett P.M., Ahmed M.L., Dunger D.B. Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: Longitudinal birth cohort study and analysis. Pediatr. Res. 2002, 52:863-867.
40. Ong K.K.L., Ahmed M.L., Sherriff A., Woods K.A., Watts A., Golding J., Dunger D.B. Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans. J. Clin. Endocrinol. Metab. 1999, 84:1145-1148.
41. Osgerby J.C., Gadd T.S., Wathes D.C. The effects of maternal nutrition and body condition on placental and foetal growth in the ewe. Placenta 2003, 24:236-247.
42. Pomp D., Zou T., Clutter A.C., Barendse W. Rapid communication: Mapping of leptin to bovine chromosome 4 by linkage analysis of a PCR-based polymorphism. J. Anim. Sci. 1997, 75:1427.
43. Sadeghi M., Moradi Shahr Babak M., Rahimi G., Nejati Javaremi A. Effect of leptin gene polymorphism on the breeding value of milk production traits in Iranian Holstein. Animal 2008, 2:999-1002.
44. Sagawa N., Yura S., Itoh H., Mise H., Kakui K., Korita D., Takemura M., Nuamah M.A., Ogawa Y., Masuzaki H., Nakao K., Fujii S. Role of leptin in pregnancy-A review. Placenta 2002, 23:S80-S86.
45. Schenkel F.S., Miller S.P., Ye X., Moore S.S., Nkrumah J.D., Li C., Yu J., Mandell I.B., Wilton J.W., Williams J.L. Association of single nucleotide polymorphisms in the leptin gene with carcass and meat quality traits of beef cattle. J. Anim. Sci. 2005, 83:2009-2020.
46. Steinbock L., Nasholm A., Berglund B., Johansson K., Philipsson J. Genetic effects on stillbirth and calving difficulty in Swedish Holsteins at first and second calving. J. Dairy Sci. 2003, 86:2228-2235.
47. Swali A., Wathes D.C. Influence of primiparity on size at birth, growth, the somatotropic axis and fertility in dairy heifers. Anim. Reprod. Sci. 2007, 102:122-136.
48. Thomas L., Wallace J.M., Aitken R.P., Mercer J.G., Trayhurn P., Hoggard N. Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome. J. Endocrinol. 2001, 169:465-476.
49. Thomasen J.R., Guldbrandtsen B., Sørensen P., Thomsen B., Lund M.S. Quantitative trait loci affecting calving traits in Danish Holstein cattle. J. Dairy Sci. 2008, 91:2098-2105.
50. Thorn S.R., Meyer M.J., Van Amburgh M.E., Boisclair Y.R. Effect of estrogen on leptin and expression of leptin receptor transcripts in prepubertal dairy heifers. J. Dairy Sci. 2007, 90:3742-3750.
51. Torday J.S., Sun H., Wang L., Torres E., Sunday M.E., Rubin L.P. Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am. J. Physiol. Lung Cell. Mol. Physiol. 2002, 282:L405-L410.
52. Toth B., Bastug M., Scholz C., Arck P., Schulze S., Kunze S., Friese K., Jeschke U. Leptin and peroxisome proliferator-activated receptors: Impact on normal and disturbed first trimester human pregnancy. Histol. Histopathol. 2008, 23:1465-1475.
53. Toth B., Fischl A., Scholz C., Kuhn C., Friese K., Karamouti M., Makrigiannakis A., Jeschke U. Insulin and leptin receptors as possible new candidates for endocrine control in normal and disturbed human pregnancy. Mol. Hum. Reprod. 2009, 15:231-239.
54. Vaskú J.A., Vaskú A., Dostálová Z., Bienert P. Association of leptin genetic polymorphism -2548 G/A with gestational diabetes mellitus. Genes Nutr. 2006, 1:117-123.
55. Wilsher S., Allen W.R. The effects of maternal age and parity on placental and fetal development in the mare. Equine Vet. J. 2003, 35:476-483.
56. Yamashita H., Shao J., Ishizuka T., Klepcyk P.J., Muhlenkamp P., Qiao L., Hoggard N., Friedman J.E. Leptin administration prevents spontaneous gestational diabetes in heterozygous Lepr(db/+) mice: Effects on placental leptin and fetal growth. Endocrinology 2001, 142:2888-2897.