Leptin secretion to both the maternal and fetal circulation in the ex vivo perfused human term placenta

Placenta

Volumn 22, Issue 4, 2001, Pages 347-352

  Hoggard, N ^a   Crabtree, J ^a   Allstaff, S ^b   Abramovich, D R ^b   Haggarty, P ^a,b  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; FAT; LEPTIN; OXYGEN;

ARTICLE; BIRTH WEIGHT; BLOOD CARBON DIOXIDE TENSION; BLOOD OXYGEN TENSION; BLOOD PH; BODY MASS; CONTROLLED STUDY; FEMALE; FETUS CIRCULATION; FETUS WEIGHT; GESTATIONAL AGE; HORMONE RELEASE; HORMONE SYNTHESIS; HORMONE TRANSPORT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MATERNAL BLOOD; MOTHER; PLACENTA PERFUSION; PLACENTA WEIGHT; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

EID: 0034970748     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2001.0628     Document Type: Article

References (40)

1. Identification of a placental enhancer for the human leptin gene
2. Stereological re-examination of the effects of varying oxygen-tensions on human placental villi maintained in organ-culture for up to 12-H
3. Fetal plasma leptin concentrations: Relationship with different intrauterine growth patterns from 19 weeks to term
4. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
5. Early onset of reproductive function in normal female mice treated with leptin
6. Identification of the human leptin 5′-flanking sequences involved in the trophoblast-specific transcription
7. Postnatal changes of leptin levels in full-term and preterm neonates: Their relation to intrauterine growth, gender and testosterone
8. Leptin values in placental cord blood of human newborns with normal intrauterine growth after 30-42 weeks of gestation
9. Plasma leptin concentrations in newborns of diabetic and nondiabetic mothers
10. Effect of maternal polyunsaturated fatty acid concentration on transport by the human placenta
11. Long-chain polyunsaturated fatty acid transport across the perfused human placenta
12. Circulating leptin in women: A longitudinal study in the menstrual cycle and during pregnancy
13. Circulating leptin levels are modulated by fasting, cold-exposure and insulin administration in lean but not zucker (Fa/Fa) rats as Mmasured by ELISA
14. Relationship between concentration of serum leptin and fetal growth
15. Placental leptin: An important new growth factor in intrauterine and neonatal development?
16. Expression of placental leptin and leptin receptor transcripts in early pregnancy and at term
17. Ontogeny of leptin in human fetuses and newborns: Effect of intrauterine growth retardation on serum leptin concentrations
18. Placental villous glucose metabolism and hormone release respond to varying oxygen tensions
19. Leptin concentration in cord blood correlates with intrauterine growth
20. Transfer of cocaine by the perfused human placenta: The effect of binding to serum proteins
21. Placental leptin in normal diabetic and fetal growth retarted pregnancies
22. Effect of birth weight and maternal smoking on cord blood leptin concentrations of full-term and preterm newborns
23. Plasma leptin in infants: Relations to birth weight and weight loss
24. Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
25. Serum leptin concentration in cord blood: Relationship to birthweight and gender
26. Augmented placental production of leptin in pre-eclampsia: Possible involvement of placental hypoxia
27. Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans
28. Obesity-A modern-day epidemic
29. Placental oxygen consumption. Part II: In vitro studies-a review
30. Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: Relation to neonatal and placental weight
31. Synthesis of leptin in human placenta
32. Neonatal cord blood leptin: Its relationship to birth weight, body mass index, maternal diabetes, and steroids
33. Leptin is present in human cord blood
34. An estimate of the caloric requirements of the human fetus
35. Sex-based differences in serum leptin concentrations from umbilical cord blood at delivery
36. Increase of mouse leptin production by adipose tissue after midpregnancy: Gestational profile of serum leptin concentration
37. Leptin: Fundamental aspects
38. Cord blood leptin concentrations in relation to intrauterine growth
39. A positive umbilical venous-arterial difference of leptin level and its rapid decline after birth
40. Augmentation of leptin synthesis and secretion through activation of protein kinases A and C in cultured human trophoblastic cells