HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK

Molecular and Cellular Biology

Volumn 30, Issue 6, 2010, Pages 1541-1554

  Lin, Qiong ^a   Wang, Jian ^a   Childress, Chandra ^a   Sudol, Marius ^a   Carey, David J ^a   Yang, Wannian ^a  

^a WEIS CENTER FOR RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CDC42 ASSOCIATED TYROSINE KINASE; BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEASOME; PROTEIN TYROSINE KINASE; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STERILE ALPHA MOTIF DOMAIN; UBIQUITINATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CONSERVED SEQUENCE; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; EPIDERMAL GROWTH FACTOR; GENE KNOCKDOWN TECHNIQUES; HUMANS; LYSOSOMES; MICE; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 77749323390     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00013-10     Document Type: Article

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