Contributions of the histidine side chain and the n-terminal a-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH

Biochemistry

Volumn 49, Issue 9, 2010, Pages 2018-2030

  Ballin, Jeff D ^a   Prevas, James P ^a   Ross, Christina R ^a   Toth, Eric A ^a   Wilson, Gerald M ^a   Thomas Record Jr , M ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; BINDING INTERFACE; BINDING PROCESS; BINDING THERMODYNAMICS; BRIDGE FORMATION; COULOMBIC INTERACTIONS; EQUILIBRIUM BINDING CONSTANT; MODEL PEPTIDES; N-TERMINALS; NATIVE PROTEINS; OLIGOPEPTIDES; PH-DEPENDENCE; PROTEIN-NUCLEIC ACIDS; PROTON UPTAKE; PROTONATED; PROTONATED HISTIDINE; SALT CONCENTRATION; SIDE CHAINS; SPECIFIC INTERACTION; TITRATION CURVES; TRYPTOPHAN FLUORESCENCE;

AMINO ACIDS; BIOMOLECULES; EQUILIBRIUM CONSTANTS; NUCLEIC ACIDS; OPTICAL SWITCHES; PEPTIDES; PROTONATION; RNA; THERMODYNAMICS;

PHOSPHATASES;

AMINO ACID DERIVATIVE; HISTIDYLTRYPTOPHANYLLYSYLLYSINAMIDE; LYSINE; LYSYLTRYPTOPHANYLLYSYLLYSINAMIDE; NUCLEIC ACID; OLIGOPEPTIDE; POLYELECTROLYTE; POLYURIDYLIC ACID; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; COMPLEMENT FIXATION; DNA BINDING; FLUORESCENCE; HYDRATION; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTON TRANSPORT; THERMODYNAMICS; TITRIMETRY;

AMINO ACID SEQUENCE; ANIMALS; DNA-BINDING PROTEINS; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; POLY U; PROTEIN BINDING; PROTONS; RNA; RNA-BINDING PROTEINS; THERMODYNAMICS;

KOBUS;

EID: 77749289844     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902027z     Document Type: Article

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