메뉴 건너뛰기




Volumn 34, Issue 3, 2010, Pages 451-461

Neuropeptide y Signaling in the central nucleus of amygdala regulates alcohol-drinking and anxiety-like behaviors of alcohol-preferring rats

Author keywords

Alcohol Preference; Amygdala; Anxiety; CREB; Neuropeptide Y; P Rat

Indexed keywords

ALCOHOL; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; NEUROPEPTIDE Y;

EID: 77749283313     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.01109.x     Document Type: Article
Times cited : (63)

References (72)
  • 1
    • 0027978406 scopus 로고
    • Intracerebroventricular injection of dibutyryl cyclic adenosine 3', 5'-monophosphate increases hypothalamic levels of neuropeptide y
    • Akabayashi A, Zaia CT, Gabriel SM, Silva I, Cheung WK, Leibowitz SF (1994) Intracerebroventricular injection of dibutyryl cyclic adenosine 3', 5'-monophosphate increases hypothalamic levels of neuropeptide Y. Brain Res 660 : 323 328.
    • (1994) Brain Res , vol.660 , pp. 323-328
    • Akabayashi, A.1    Zaia, C.T.2    Gabriel, S.M.3    Silva, I.4    Cheung, W.K.5    Leibowitz, S.F.6
  • 3
    • 33846622462 scopus 로고    scopus 로고
    • Neuropeptide y modulation of ethanol intake: Effects of ethanol drinking history and genetic background
    • Badia-Elder NE, Gilpin NW, Stewart RB (2007) Neuropeptide Y modulation of ethanol intake: effects of ethanol drinking history and genetic background. Peptides 28 : 339 344.
    • (2007) Peptides , vol.28 , pp. 339-344
    • Badia-Elder, N.E.1    Gilpin, N.W.2    Stewart, R.B.3
  • 4
    • 0038714314 scopus 로고    scopus 로고
    • Effects of neuropeptide y on sucrose and ethanol intake and on anxiety-like behavior in high alcohol drinking (HAD) and low alcohol drinking (LAD) rats
    • Badia-Elder NE, Stewart RB, Powrozek TA, Murphy JM, Li T-K (2003) Effects of neuropeptide Y on sucrose and ethanol intake and on anxiety-like behavior in high alcohol drinking (HAD) and low alcohol drinking (LAD) rats. Alcohol Clin Exp Res 27 : 894 899.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 894-899
    • Badia-Elder, N.E.1    Stewart, R.B.2    Powrozek, T.A.3    Murphy, J.M.4    Li, T.-K.5
  • 5
    • 0035106435 scopus 로고    scopus 로고
    • Effect of neuropeptide Y(NPY) on oral ethanol intake in Wistar, alcohol-preferring (P), and -non preferring (NP) rats
    • Badia-Elder NE, Stewart RB, Powrozek TA, Roy KF, Murphy JM, Li T-K (2001) Effect of neuropeptide Y(NPY) on oral ethanol intake in Wistar, alcohol-preferring (P), and -non preferring (NP) rats. Alcohol Clin Exp Res 25 : 386 390.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 386-390
    • Badia-Elder, N.E.1    Stewart, R.B.2    Powrozek, T.A.3    Roy, K.F.4    Murphy, J.M.5    Li, T.-K.6
  • 6
    • 0030840674 scopus 로고    scopus 로고
    • Y-receptor subtypes-how many more?
    • Blomqvist AG, Herzog H (1997) Y-receptor subtypes-how many more? Trends Neurosci 20 : 294 298.
    • (1997) Trends Neurosci , vol.20 , pp. 294-298
    • Blomqvist, A.G.1    Herzog, H.2
  • 7
    • 0021248888 scopus 로고
    • Neuropeptide y and human pancreatic polypeptide stimulate feeding behavior in rats
    • Clark JT, Kalra PS, Crowley WR, Kalra SP (1984) Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115 : 427 429.
    • (1984) Endocrinology , vol.115 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.R.3    Kalra, S.P.4
  • 8
    • 0042694131 scopus 로고    scopus 로고
    • Pharmacogenomics of alcohol response and addiction
    • Enoch MA (2003) Pharmacogenomics of alcohol response and addiction. Am J Pharmacogenomics 3 : 217 232.
    • (2003) Am J Pharmacogenomics , vol.3 , pp. 217-232
    • Enoch, M.A.1
  • 9
    • 44649182704 scopus 로고    scopus 로고
    • Neuropeptide y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking
    • Gilpin NW, Misra K, Koob GF (2008) Neuropeptide Y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking. Pharmacol Biochem Behav 90 : 475 480.
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 475-480
    • Gilpin, N.W.1    Misra, K.2    Koob, G.F.3
  • 10
    • 0030612057 scopus 로고    scopus 로고
    • Neuropeptide y and [Leu31, Pro34] neuropeptide y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat
    • Hastings JA, Pavia JM, Morris MJ (1997) Neuropeptide Y and [Leu31, Pro34] neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat. Brain Res 750 : 301 304.
    • (1997) Brain Res , vol.750 , pp. 301-304
    • Hastings, J.A.1    Pavia, J.M.2    Morris, M.J.3
  • 11
    • 0027265205 scopus 로고
    • Anxiolytic-like action of neuropeptide Y: Mediation by Y1 receptors in amygdala, and dissociation from food intake effects
    • Heilig M, McLeod S, Brot M, Heinrichs SC, Menzaghi F, Koob GF, Britton KT (1993) Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology 8 : 357 363.
    • (1993) Neuropsychopharmacology , vol.8 , pp. 357-363
    • Heilig, M.1    McLeod, S.2    Brot, M.3    Heinrichs, S.C.4    Menzaghi, F.5    Koob, G.F.6    Britton, K.T.7
  • 12
    • 0025045020 scopus 로고
    • Neuropeptide Y: An overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses
    • Heilig M, Widerlöv E (1990) Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses. Acta Psychiatr Scand 82 : 95 114.
    • (1990) Acta Psychiatr Scand , vol.82 , pp. 95-114
    • Heilig, M.1    Widerlöv, E.2
  • 13
    • 0028799150 scopus 로고
    • Neurobiology and clinical aspects of neuropeptide y
    • Heilig M, Widerlöv E (1995) Neurobiology and clinical aspects of neuropeptide Y. Crit Rev Neurobiol 9 : 115 136.
    • (1995) Crit Rev Neurobiol , vol.9 , pp. 115-136
    • Heilig, M.1    Widerlöv, E.2
  • 14
    • 0023917334 scopus 로고
    • Rat neuropeptide y precursor gene expression: MRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester
    • Higuchi H, Yang HY, Sabol SL (1988) Rat neuropeptide Y precursor gene expression: mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester. J Biol Chem 263 : 6288 6295.
    • (1988) J Biol Chem , vol.263 , pp. 6288-6295
    • Higuchi, H.1    Yang, H.Y.2    Sabol, S.L.3
  • 15
    • 0032981008 scopus 로고    scopus 로고
    • Innate differences of neuropeptide y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference
    • Hwang BH, Zhang J-K, Ehlers CL, Lumeng L, Li T-K (1999) Innate differences of neuropeptide Y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference. Alcohol Clin Exp Res 23 : 1023 1030.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 1023-1030
    • Hwang, B.H.1    Zhang, J.-K.2    Ehlers, C.L.3    Lumeng, L.4    Li, T.-K.5
  • 17
    • 0033136259 scopus 로고    scopus 로고
    • Making new connections: Role of ERK/MAP kinase signaling in neuronal plasticity
    • Impey S, Obrietan K, Storm DR (1999) Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 23 : 11 14.
    • (1999) Neuron , vol.23 , pp. 11-14
    • Impey, S.1    Obrietan, K.2    Storm, D.R.3
  • 18
    • 20344396333 scopus 로고    scopus 로고
    • Mild anxiogenic effects of nicotine withdrawal in mice
    • Jonkman S, Henry B, Semenova S, Markou A (2005) Mild anxiogenic effects of nicotine withdrawal in mice. Eur J Pharmacol 516 : 40 45.
    • (2005) Eur J Pharmacol , vol.516 , pp. 40-45
    • Jonkman, S.1    Henry, B.2    Semenova, S.3    Markou, A.4
  • 20
    • 0037329682 scopus 로고    scopus 로고
    • Alcoholism: Allostasis and beyond
    • Koob GF (2003) Alcoholism: allostasis and beyond. Alcohol Clin Exp Res 27 : 232 243.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 232-243
    • Koob, G.F.1
  • 22
    • 4344645299 scopus 로고    scopus 로고
    • Molecular evolution of NPY receptor subtypes
    • Larhammar D, Salaneck E (2004) Molecular evolution of NPY receptor subtypes. Neuropeptides 38 : 141 151.
    • (2004) Neuropeptides , vol.38 , pp. 141-151
    • Larhammar, D.1    Salaneck, E.2
  • 23
    • 0027324698 scopus 로고
    • Selective breeding for alcohol preference and associated responses
    • Li T-K, Lumeng L, Doolittle DP (1993) Selective breeding for alcohol preference and associated responses. Behav Genet 23 : 163 170.
    • (1993) Behav Genet , vol.23 , pp. 163-170
    • Li, T.-K.1    Lumeng, L.2    Doolittle, D.P.3
  • 24
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • Lonze BE, Ginty DD (2002) Function and regulation of CREB family transcription factors in the nervous system. Neuron 35 : 605 623.
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 25
    • 0036159713 scopus 로고    scopus 로고
    • Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents
    • McBride WJ (2002) Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents. Pharmacol Biochem Behav 71 : 509 515.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 509-515
    • McBride, W.J.1
  • 26
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • McBride WJ, Li T-K (1998) Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol 12 : 339 369.
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.-K.2
  • 27
    • 36248941186 scopus 로고    scopus 로고
    • Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide y
    • Meurs A, Clinckers R, Ebinger G, Michotte Y, Smolders I (2007) Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. Eur J Neurosci 26 : 3079 3092.
    • (2007) Eur J Neurosci , vol.26 , pp. 3079-3092
    • Meurs, A.1    Clinckers, R.2    Ebinger, G.3    Michotte, Y.4    Smolders, I.5
  • 28
    • 0025908658 scopus 로고
    • Receptors for neuropeptide Y: Multiple subtypes and multiple second messengers
    • Michel MC (1991) Receptors for neuropeptide Y: multiple subtypes and multiple second messengers. Trends Pharmacol Sci 12 : 389 394.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 389-394
    • Michel, M.C.1
  • 29
    • 33745218286 scopus 로고    scopus 로고
    • The decreased cyclic-AMP dependent-protein kinase A function in the nucleus accumbens: A role in alcohol drinking but not in anxiety-like behaviors in rats
    • Misra K, Pandey SC (2006) The decreased cyclic-AMP dependent-protein kinase A function in the nucleus accumbens: a role in alcohol drinking but not in anxiety-like behaviors in rats. Neuropsychopharmacology 31 : 1406 1419.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1406-1419
    • Misra, K.1    Pandey, S.C.2
  • 30
    • 0343488556 scopus 로고    scopus 로고
    • Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions
    • Möller C, Wiklund L, Sommer W, Thorsell A, Heilig M (1997) Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions. Brain Res 760 : 94 101.
    • (1997) Brain Res , vol.760 , pp. 94-101
    • Möller, C.1    Wiklund, L.2    Sommer, W.3    Thorsell, A.4    Heilig, M.5
  • 31
    • 18844456515 scopus 로고    scopus 로고
    • A novel single nucleotide polymorphism of the neuropeptide y (NPY) gene associated with alcohol dependence
    • Mottagui-Tabar S, Prince JA, Wahlestedt C, Zhu G, Goldman D, Heilig M (2005) A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcohol Clin Exp Res 29 : 702 707.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 702-707
    • Mottagui-Tabar, S.1    Prince, J.A.2    Wahlestedt, C.3    Zhu, G.4    Goldman, D.5    Heilig, M.6
  • 32
    • 0036751424 scopus 로고    scopus 로고
    • Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference
    • Murphy JM, Stewart RB, Bell RL, Badia-Elder NE, Carr LG, McBride WJ, Lumeng L, Li T-K (2002) Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference. Behav Genet 32 : 363 388.
    • (2002) Behav Genet , vol.32 , pp. 363-388
    • Murphy, J.M.1    Stewart, R.B.2    Bell, R.L.3    Badia-Elder, N.E.4    Carr, L.G.5    McBride, W.J.6    Lumeng, L.7    Li, T.-K.8
  • 33
    • 0037288904 scopus 로고    scopus 로고
    • Anxiety sensitivity, self-reported motives for alcohol and nicotine use, and level of consumption
    • Novak A, Burgess ES, Clark M, Zvolensky MJ, Brown RA (2003) Anxiety sensitivity, self-reported motives for alcohol and nicotine use, and level of consumption. J Anxiety Disord 17 : 165 180.
    • (2003) J Anxiety Disord , vol.17 , pp. 165-180
    • Novak, A.1    Burgess, E.S.2    Clark, M.3    Zvolensky, M.J.4    Brown, R.A.5
  • 34
    • 0034990090 scopus 로고    scopus 로고
    • Polymorphism of the neuropeptide Y gene: An association study with alcohol withdrawal
    • Okubo T, Harada S (2001) Polymorphism of the neuropeptide Y gene: an association study with alcohol withdrawal. Alcohol Clin Exp Res 25 : 59S 62S. (Pubitemid 32553353)
    • (2001) Alcoholism: Clinical and Experimental Research , vol.25 , Issue.SUPPL.
    • Okubo, T.1    Harada, S.2
  • 35
    • 0041878695 scopus 로고    scopus 로고
    • Anxiety and alcohol abuse disorders: A common role for CREB and its target, the neuropeptide y gene
    • Pandey SC (2003) Anxiety and alcohol abuse disorders: a common role for CREB and its target, the neuropeptide Y gene. Trends Pharmacol Sci 24 : 456 460.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 456-460
    • Pandey, S.C.1
  • 36
    • 6944240230 scopus 로고    scopus 로고
    • The gene transcription factor cyclic AMP-responsive element binding protein: Role in positive and negative affective states of alcohol addiction
    • Pandey SC (2004) The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of alcohol addiction. Pharmacol Ther 104 : 47 58.
    • (2004) Pharmacol Ther , vol.104 , pp. 47-58
    • Pandey, S.C.1
  • 38
    • 0035123295 scopus 로고    scopus 로고
    • Effects of chronic ethanol intake and its withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat cortex
    • Pandey SC, Roy A, Mittal N (2001) Effects of chronic ethanol intake and its withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat cortex. J Pharmacol Exp Ther 296 : 857 868. (Pubitemid 32187358)
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.296 , Issue.3 , pp. 857-868
    • Pandey, S.C.1    Roy, A.2    Mittal, N.3
  • 39
    • 0037346976 scopus 로고    scopus 로고
    • The decreased phosphorylation of cyclic adenosine monophosphate (cAMP) response element binding (CREB) protein in the central amygdala acts as a molecular substrate for anxiety related to ethanol withdrawal in rats
    • Pandey SC, Roy A, Zhang H (2003b) The decreased phosphorylation of cyclic adenosine monophosphate (cAMP) response element binding (CREB) protein in the central amygdala acts as a molecular substrate for anxiety related to ethanol withdrawal in rats. Alcohol Clin Exp Res 27 : 396 409.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 396-409
    • Pandey, S.C.1    Roy, A.2    Zhang, H.3
  • 40
    • 2542577905 scopus 로고    scopus 로고
    • Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors
    • Pandey SC, Roy A, Zhang H, Xu T (2004) Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors. J Neurosci 24 : 5022 5030.
    • (2004) J Neurosci , vol.24 , pp. 5022-5030
    • Pandey, S.C.1    Roy, A.2    Zhang, H.3    Xu, T.4
  • 41
    • 43649105135 scopus 로고    scopus 로고
    • Brain chromatin remodeling: A novel mechanism of alcoholism
    • Pandey SC, Ugale R, Zhang H, Tang L, Prakash A (2008) Brain chromatin remodeling: a novel mechanism of alcoholism. J Neurosci 28 : 3729 3737.
    • (2008) J Neurosci , vol.28 , pp. 3729-3737
    • Pandey, S.C.1    Ugale, R.2    Zhang, H.3    Tang, L.4    Prakash, A.5
  • 42
    • 33748131853 scopus 로고    scopus 로고
    • Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors
    • Pandey SC, Zhang H, Roy A, Misra K (2006) Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors. J Neurosci 26 : 8320 8331.
    • (2006) J Neurosci , vol.26 , pp. 8320-8331
    • Pandey, S.C.1    Zhang, H.2    Roy, A.3    Misra, K.4
  • 43
    • 26444506279 scopus 로고    scopus 로고
    • Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism
    • Pandey SC, Zhang H, Roy A, Xu T (2005) Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. J Clin Invest 115 : 2762 2773.
    • (2005) J Clin Invest , vol.115 , pp. 2762-2773
    • Pandey, S.C.1    Zhang, H.2    Roy, A.3    Xu, T.4
  • 44
    • 0032942627 scopus 로고    scopus 로고
    • Genetic and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins
    • Prescott CA, Kendler KS (1999) Genetic and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins. Am J Psychiatry 156 : 34 40.
    • (1999) Am J Psychiatry , vol.156 , pp. 34-40
    • Prescott, C.A.1    Kendler, K.S.2
  • 45
    • 33645979010 scopus 로고    scopus 로고
    • Over expression of neuropeptide y in the central nucleus of the amygdala decreases ethanol self-administration in "anxious" rats
    • Primeaux SD, Wilson SP, Bray GA, York DA, Wilson MA (2006) Over expression of neuropeptide Y in the central nucleus of the amygdala decreases ethanol self-administration in "anxious" rats. Alcohol Clin Exp Res 30 : 791 801.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 791-801
    • Primeaux, S.D.1    Wilson, S.P.2    Bray, G.A.3    York, D.A.4    Wilson, M.A.5
  • 46
    • 0035060492 scopus 로고    scopus 로고
    • Pharmacogenetics of alcohol response and alcoholism: The interplay of genes and environmental factors in thresholds for alcoholism
    • Radel M, Goldman D (2001) Pharmacogenetics of alcohol response and alcoholism: the interplay of genes and environmental factors in thresholds for alcoholism. Drug Metab Dispos 29 : 489 494.
    • (2001) Drug Metab Dispos , vol.29 , pp. 489-494
    • Radel, M.1    Goldman, D.2
  • 48
    • 0035998897 scopus 로고    scopus 로고
    • The decreased cellular expression of neuropeptide y protein in rat brain structures during ethanol withdrawal after chronic ethanol exposure
    • Roy A, Pandey SC (2002) The decreased cellular expression of neuropeptide Y protein in rat brain structures during ethanol withdrawal after chronic ethanol exposure. Alcohol Clin Exp Res 26 : 796 803.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 796-803
    • Roy, A.1    Pandey, S.C.2
  • 49
    • 0000952642 scopus 로고    scopus 로고
    • Performance in the cross-maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior
    • Salimov RM, McBride WJ, Sinclair JD, Lumeng L, Li T (1996) Performance in the cross-maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior. Addict Biol 1 : 273 280.
    • (1996) Addict Biol , vol.1 , pp. 273-280
    • Salimov, R.M.1    McBride, W.J.2    Sinclair, J.D.3    Lumeng, L.4    Li, T.5
  • 50
    • 0347625642 scopus 로고    scopus 로고
    • Neuropeptide-Y Y5 receptors modulate the onset and maintenance of operant ethanol self-administration
    • Schroeder JP, Iller KA, Hodge CW (2003) Neuropeptide-Y Y5 receptors modulate the onset and maintenance of operant ethanol self-administration. Alcohol Clin Exp Res 27 : 1912 1920.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 1912-1920
    • Schroeder, J.P.1    Iller, K.A.2    Hodge, C.W.3
  • 51
    • 29244454565 scopus 로고    scopus 로고
    • The neuropeptide-Y Y5 receptor antagonist L-152,804 decreases alcohol self-administration in inbred alcohol-preferring (iP) rats
    • Schroeder JP, Overstreet DH, Hodge CW (2005) The neuropeptide-Y Y5 receptor antagonist L-152,804 decreases alcohol self-administration in inbred alcohol-preferring (iP) rats. Alcohol 36 : 179 186.
    • (2005) Alcohol , vol.36 , pp. 179-186
    • Schroeder, J.P.1    Overstreet, D.H.2    Hodge, C.W.3
  • 52
    • 0031002007 scopus 로고    scopus 로고
    • Neuropeptide y treatment and food deprivation increase cyclic AMP response element-binding in rat hypothalamus
    • Sheriff S, Chance WT, Fischer JE, Balasubramaniam A (1997) Neuropeptide Y treatment and food deprivation increase cyclic AMP response element-binding in rat hypothalamus. Mol Pharmacol 51 : 597 604.
    • (1997) Mol Pharmacol , vol.51 , pp. 597-604
    • Sheriff, S.1    Chance, W.T.2    Fischer, J.E.3    Balasubramaniam, A.4
  • 53
    • 0032566803 scopus 로고    scopus 로고
    • NPY upregulates genes containing cyclic AMP response element in human neuroblastoma cell lines bearing Y1 and Y2 receptors: Involvement of CREB
    • Sheriff S, Dayal R, Kasckow J, Regmi A, Chance W, Fischer J, Balasubramaniam A (1998) NPY upregulates genes containing cyclic AMP response element in human neuroblastoma cell lines bearing Y1 and Y2 receptors: involvement of CREB. Regul Pept 75-76 : 309 318.
    • (1998) Regul Pept , vol.7576 , pp. 309-318
    • Sheriff, S.1    Dayal, R.2    Kasckow, J.3    Regmi, A.4    Chance, W.5    Fischer, J.6    Balasubramaniam, A.7
  • 54
  • 55
    • 31344432054 scopus 로고    scopus 로고
    • Comparison of anxiety-like behavior in adolescent and adult Sprague-Dawley rats
    • Slawecki CJ (2005) Comparison of anxiety-like behavior in adolescent and adult Sprague-Dawley rats. Behav Neurosci 119 : 1477 1483.
    • (2005) Behav Neurosci , vol.119 , pp. 1477-1483
    • Slawecki, C.J.1
  • 56
    • 0033137329 scopus 로고    scopus 로고
    • 2+-calmodulin-dependent protein kinase cascade
    • 2+-calmodulin-dependent protein kinase cascade. Trends Biochem Sci 24 : 232 236.
    • (1999) Trends Biochem Sci , vol.24 , pp. 232-236
    • Soderling, T.R.1
  • 57
    • 34548039480 scopus 로고    scopus 로고
    • Elevated anxiety-like behavior following ethanol exposure in mutant mice lacking neuropeptide y (NPY)
    • Sparta DR, Fee JR, Knapp DJ, Breese GR, Thiele TE (2007) Elevated anxiety-like behavior following ethanol exposure in mutant mice lacking neuropeptide Y (NPY). Drug Alcohol Depend 90 : 297 300.
    • (2007) Drug Alcohol Depend , vol.90 , pp. 297-300
    • Sparta, D.R.1    Fee, J.R.2    Knapp, D.J.3    Breese, G.R.4    Thiele, T.E.5
  • 58
    • 14644390950 scopus 로고    scopus 로고
    • Effect of polymorphism on expression of the neuropeptide y gene in inbred alcohol-preferring and -nonpreferring rats
    • Spence JP, Liang T, Habegger K, Carr LG (2005) Effect of polymorphism on expression of the neuropeptide Y gene in inbred alcohol-preferring and -nonpreferring rats. Neuroscience 131 : 871 876.
    • (2005) Neuroscience , vol.131 , pp. 871-876
    • Spence, J.P.1    Liang, T.2    Habegger, K.3    Carr, L.G.4
  • 59
    • 0027516283 scopus 로고
    • Comparison of alcohol-preferring (P) and non-preferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol
    • Stewart RB, Gatto GJ, Lumeng L, Li T-K, Murphy JM (1993) Comparison of alcohol-preferring (P) and non-preferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol 10 : 1 10.
    • (1993) Alcohol , vol.10 , pp. 1-10
    • Stewart, R.B.1    Gatto, G.J.2    Lumeng, L.3    Li, T.-K.4    Murphy, J.M.5
  • 60
    • 2942744339 scopus 로고    scopus 로고
    • Reduced neuropeptide y mRNA expression in the central nucleus of amygdala of alcohol preferring (P) rats: Its potential involvement in alcohol preference and anxiety
    • Suzuki R, Lumeng L, McBride WJ, Li T-K, Hwang BH (2004) Reduced neuropeptide Y mRNA expression in the central nucleus of amygdala of alcohol preferring (P) rats: its potential involvement in alcohol preference and anxiety. Brain Res 1014 : 251 254.
    • (2004) Brain Res , vol.1014 , pp. 251-254
    • Suzuki, R.1    Lumeng, L.2    McBride, W.J.3    Li, T.-K.4    Hwang, B.H.5
  • 61
    • 4344691974 scopus 로고    scopus 로고
    • Voluntary alcohol consumption is controlled via the neuropeptide y Y1 receptor
    • Thiele TE, Koh MT, Pedrazzini T (2002) Voluntary alcohol consumption is controlled via the neuropeptide Y Y1 receptor. J Neurosci 22 : RC208.
    • (2002) J Neurosci , vol.22 , pp. 208
    • Thiele, T.E.1    Koh, M.T.2    Pedrazzini, T.3
  • 62
    • 0032569940 scopus 로고    scopus 로고
    • Ethanol consumption and resistance are inversely related to neuropeptide y levels
    • Thiele TE, Marsh DJ, Ste Marie L, Bernstein IL, Palmiter RD (1998) Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature 396 : 366 369.
    • (1998) Nature , vol.396 , pp. 366-369
    • Thiele, T.E.1    Marsh, D.J.2    Ste Marie, L.3    Bernstein, I.L.4    Palmiter, R.D.5
  • 63
    • 2942537938 scopus 로고    scopus 로고
    • Assessment of ethanol consumption and water drinking by NPY Y(2) receptor knockout mice
    • Thiele TE, Naveilhan P, Ernfors P (2004) Assessment of ethanol consumption and water drinking by NPY Y(2) receptor knockout mice. Peptides 25 : 975 983.
    • (2004) Peptides , vol.25 , pp. 975-983
    • Thiele, T.E.1    Naveilhan, P.2    Ernfors, P.3
  • 64
    • 0036552411 scopus 로고    scopus 로고
    • Diverse functions of neuropeptide y revealed using genetically modified animals
    • Thorsell A, Heilig M (2002) Diverse functions of neuropeptide Y revealed using genetically modified animals. Neuropeptides 36 : 182 193.
    • (2002) Neuropeptides , vol.36 , pp. 182-193
    • Thorsell, A.1    Heilig, M.2
  • 65
    • 34249685489 scopus 로고    scopus 로고
    • Viral vector-induced amygdala NPY over expression reverses increased alcohol intake caused by repeated deprivations in Wistar rats
    • Thorsell A, Repunte-Canonigo V, O'Dell LE, Chen SA, King AR, Lekic D, Koob GF, Sanna PP (2007) Viral vector-induced amygdala NPY over expression reverses increased alcohol intake caused by repeated deprivations in Wistar rats. Brain 130 : 1330 1337.
    • (2007) Brain , vol.130 , pp. 1330-1337
    • Thorsell, A.1    Repunte-Canonigo, V.2    O'Dell, L.E.3    Chen, S.A.4    King, A.R.5    Lekic, D.6    Koob, G.F.7    Sanna, P.P.8
  • 66
    • 0037174775 scopus 로고    scopus 로고
    • Blockade of central neuropeptide y (NPY) Y2 receptors reduces ethanol self-administration in rats
    • Thorsell A, Rimondini R, Heilig M (2002) Blockade of central neuropeptide Y (NPY) Y2 receptors reduces ethanol self-administration in rats. Neurosci Lett 332 : 1 4.
    • (2002) Neurosci Lett , vol.332 , pp. 1-4
    • Thorsell, A.1    Rimondini, R.2    Heilig, M.3
  • 67
    • 17444406990 scopus 로고    scopus 로고
    • Effects of neuropeptide y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure
    • Thorsell A, Slawecki CJ, Ehlers CL (2005) Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure. Alcohol Clin Exp Res 29 : 584 590.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 584-590
    • Thorsell, A.1    Slawecki, C.J.2    Ehlers, C.L.3
  • 68
    • 0028953441 scopus 로고
    • Central nervous system pharmacology of neuropeptide y
    • Wettstein JG, Earley B, Junien JL (1995) Central nervous system pharmacology of neuropeptide Y. Pharmacol Ther 65 : 397 414.
    • (1995) Pharmacol Ther , vol.65 , pp. 397-414
    • Wettstein, J.G.1    Earley, B.2    Junien, J.L.3
  • 69
    • 33644817491 scopus 로고    scopus 로고
    • Plasma neuropeptide y concentrations in combat exposed veterans: Relationship to trauma exposure, recovery from PTSD, and coping
    • Yehuda R, Brand S, Yang RK (2006) Plasma neuropeptide Y concentrations in combat exposed veterans: relationship to trauma exposure, recovery from PTSD, and coping. Biol Psychiatry 59 : 660 663.
    • (2006) Biol Psychiatry , vol.59 , pp. 660-663
    • Yehuda, R.1    Brand, S.2    Yang, R.K.3
  • 70
    • 0347360140 scopus 로고    scopus 로고
    • Effects of PKA modulation on the expression of neuropeptide y in rat amygdaloid structures during ethanol withdrawal
    • Zhang H, Pandey SC (2003) Effects of PKA modulation on the expression of neuropeptide Y in rat amygdaloid structures during ethanol withdrawal. Peptides 24 : 1397 1402.
    • (2003) Peptides , vol.24 , pp. 1397-1402
    • Zhang, H.1    Pandey, S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.