Editorial: Common variable immunodeficiency: A heterogeneous group needs further subclassification

Expert Review of Clinical Immunology

Volumn 5, Issue 6, 2009, Pages 629-631

  Aghamohammadi, Asghar ^a,b   Parvaneh, Nima ^a,b   Rezaei, Nima ^a,b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN;

CD 19 GENE; CLINICAL FEATURE; COMMON VARIABLE IMMUNODEFICIENCY; DISEASE CLASSIFICATION; EDITORIAL; GENE; GENE IDENTIFICATION; HUMAN; ICOS GENE; INHERITANCE; MSH 5 GENE; PHENOTYPE; TNFRSF 13B GENE; TNFRSF 13C GENE;

EID: 77749253771     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/eci.09.65     Document Type: Editorial

References (35)

1. Aghamohammadi A, Farhoudi A, Moin M et al. Clinical and immunological features of 65 Iranian patients with common variable immunodeficiency. Clin. Diagn. Lab. Immunol. 12(7), 825-832 (2005).
2. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin. Immunol. 92(1), 34-48 (1999).
3. Chapel H, Lucas M, Lee M et al. Common variable immunodeficiency disorders: division into distinct clinical phenotypes. Blood 112(2), 277-286 (2008).
4. Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin. Immunol. 93(3), 190-197 (1999).
5. Khodadad A, Aghamohammadi A, Parvaneh N et al. Gastrointestinal manifestations in patients with common variable immunodeficiency. Dig. Dis. Sci. 52(11), 2977-2983 (2007).
6. Aghamohammadi A, Moin M, Farhoudi A et al. Efficacy of intravenous immunoglobulin on the prevention of pneumonia in patients with agammaglobulinemia. FEMS Immunol. Med. Microbiol. 40(2), 113-118 (2004).
7. Busse PJ, Razvi S, Cunningham-Rundles C. Efficacy of intravenous immunoglobulin in the prevention of pneumonia in patients with common variable immunodeficiency. J. Allergy Clin. Immunol. 109(6), 1001-1004 (2002).
8. Aghamohammadi A, Pouladi N, Parvaneh N et al. Mortality and morbidity in common variable immunodeficiency. J. Trop. Pediatr. 53(1), 32-38 (2007).
9. Kainulainen L, Varpula M, Liippo K, Svedstrom E, Nikoskelainen J, Ruuskanen O. Pulmonary abnormalities in patients with primary hypogammaglobulinemia. J. Allergy Clin. Immunol. 104(5), 1031-1036 (1999).
10. Thickett KM, Kumararatne DS, Banerjee AK, Dudley R, Stableforth DE. Common variable immune deficiency: respiratory manifestations, pulmonary function and high-resolution CT scan findings. Q J. Med. 95(10), 655-662 (2002).
11. Chapel H, Cunningham-Rundles C. Update in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditions. Br. J. Haematol. 145(6), 709-727 (2009).
12. Cunningham-Rundles C, Radigan L. Deficient IL-12 and dendritic cell function in common variable immune deficiency. Clin. Immunol. 115(2), 147-153 (2005).
13. Kondratenko I, Amlot PL, Webster AD, Farrant J. Lack of specific antibody response in common variable immunodeficiency (CVID) associated with failure in production of antigen-specific memory T cells. MRC Immunodeficiency Group. Clin. Exp. Immunol. 108(1), 9-13 (1997).
14. Paccani SR, Boncristiano M, Patrussi L et al. Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects. Blood 106(2), 626-634 (2005).
15. Pozzi N, Gaetaniello L, Martire B et al. Defective surface expression of attractin on T cells in patients with common variable immunodeficiency (CVID). Clin. Exp. Immunol. 123(1), 99-104 (2001).
16. Viallard JF, Camou F, Andre M et al. Altered dendritic cell distribution in patients with common variable immunodeficiency. Arthritis Res. Ther. 7(5), R1052-R1055 (2005).
17. Castigli E, Wilson SA, Garibyan L et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat. Genet. 37(8), 829-834 (2005).
18. Grimbacher B, Hutloff A, Schlesier M et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat. Immunol. 4(3), 261-268 (2003).
19. Salzer U, Chapel HM, Webster AD et al. Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat. Genet. 37(8), 820-828 (2005).
20. Sekine H, Ferreira RC, Pan-Hammarstrom Q et al. Role for Msh5 in the regulation of Ig class switch recombination. Proc. Natl Acad. Sci. USA 104(17), 7193-7198 (2007).
21. van Zelm MC, Reisli I, van der BM et al. An antibody-deficiency syndrome due to mutations in the CD19 gene. N. Engl. J. Med. 354(18), 1901-1912 (2006).
22. Warnatz K, Salzer U, Rizzi M et al. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc. Natl Acad. Sci. USA 106(33), 13945-13950 (2009).
23. Spickett GP, Webster AD, Farrant J. Cellular abnormalities in common variable immunodeficiency. Immunodefic. Rev. 2(3), 199-219 (1999).
24. Carsetti R, Rosado MM, Donnanno S et al. The loss of IgM memory B cells correlates with clinical disease in common variable immunodeficiency. J. Allergy Clin. Immunol. 115(2), 412-417 (2005).
25. Vodjgani M, Aghamohammadi A, Samadi M et al. Analysis of class-switched memory B cells in patients with common variable immunodeficiency and its clinical implications. J. Investig. Allergol. Clin. Immunol. 17(5), 321-328 (2007).
26. Bryant A, Calver NC, Toubi E, Webster AD, Farrant J. Classification of patients with common variable immunodeficiency by B cell secretion of IgM and IgG in response to anti-IgM and interleukin-2. Clin. Immunol. Immunopathol. 56(2), 239-248 (1990).
27. Piqueras B, Lavenu-Bombled C, Galicier L et al. Common variable immunodeficiency patient classification based on impaired B cell memory differentiation correlates with clinical aspects. J. Clin. Immunol. 23(5), 385-400 (2003).
28. Warnatz K, Denz A, Drager R et al. Severe deficiency of switched memory B cells (CD27+IgM-IgD-) in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease. Blood 99(5), 1544-1551 (2002).
29. Wehr C, Kivioja T, Schmitt C et al. The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood 111(1), 77-85 (2008).
30. Giovannetti A, Pierdominici M, Mazzetta F et al. Unravelling the complexity of T cell abnormalities in common variable immunodeficiency. J. Immunol. 178(6), 3932-3943 (2007).
31. Fevang B, Yndestad A, Sandberg WJ et al. Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo. Clin. Exp. Immunol. 147(3), 521-525 (2007).
32. Yu GP, Chiang D, Song SJ et al. Regulatory T cell dysfunction in subjects with common variable immunodeficiency complicated by autoimmune disease. Clin. Immunol. 131(2), 240-253 (2009).
33. Horn J, Manguiat A, Berglund LJ et al. Decrease in phenotypic regulatory T cells in subsets of patients with common variable immunodeficiency. Clin. Exp. Immunol. 156(3), 446-454 (2009).
34. Aghamohammadi A, Moin M, Kouhi A et al. Chromosomal radiosensitivity in patients with common variable immunodeficiency. Immunobiology 213(5), 447-454 (2008).
35. Rezaei N, Aghamohammadi A, Siadat SD et al. Serum bactericidal antibody responses to meningococcal polysaccharide vaccination as a basis for clinical classification of common variable immunodeficiency. Clin. Vaccine Immunol. 15(4), 607-611 (2008).