Mutational analysis of highly conserved residues in the phage PhiC31 integrase reveals key amino acids necessary for the DNA recombination

PLoS ONE

Volumn 5, Issue 1, 2010, Pages

  Liu, Shaohui ^a   Ma, Jinfang ^a   Wang, Wei ^a   Zhang, Maoxiang ^a   Xin, Qingting ^a   Peng, Siman ^a   Li, Rongxiu ^b   Zhu, Huanzhang ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; INTEGRASE; SERINE; VALINE; PRIMER DNA; VIRUS DNA;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIOPHAGE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA CLEAVAGE; DNA RECOMBINATION; ENZYME ACTIVITY; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; SITE DIRECTED MUTAGENESIS; SYNAPSE; WILD TYPE; CHEMISTRY; ENZYMOLOGY; GENETIC RECOMBINATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACIDS; BACTERIOPHAGES; BASE SEQUENCE; CONSERVED SEQUENCE; DNA PRIMERS; DNA, VIRAL; INTEGRASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECOMBINATION, GENETIC; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77749237022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008863     Document Type: Article

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