Methylation and acetylation of 15-hydroxyanandamide modulate its interaction with the endocannabinoid system

Biochimie

Volumn 92, Issue 4, 2010, Pages 378-387

  Amadio, Daniele ^a   Fezza, Filomena ^a,b   Catanzaro, Giuseppina ^b,c   Incani, Ottaviano ^d   van Zadelhoff, Guus ^e   Finazzi Agrò, Alessandro ^a   Maccarrone, Mauro ^b,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY OF TERAMO   (Italy)

^d Centre for Technology   (Italy)

^e UTRECHT UNIVERSITY   (Netherlands)

Author keywords

2 Arachidonoylglycerol; Anandamide; Fatty acid amide hydrolase; Natural inhibitors

Indexed keywords

15 ACETOXY 5,8,11,13 EICOSATETRAENOIC ACID; 15 HYDROXY 5,8,11,13 ICOSATETRAENOIC ACID; 15 HYDROXYANANDAMIDE; 15 METHOXY 5,8,11,13 EICOSATETRAENOIC ACID; 2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; ANANDAMIDE SYNTHASE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; LIPOXYGENASE; SYNTHETASE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ACETYLATION; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; ENZYME ACTIVITY; METABOLISM; METHYLATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN INTERACTION; SIMULATION; SYNTHESIS;

ACETYLATION; AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; ENDOCANNABINOIDS; KINETICS; METHYLATION; MICE; PHOSPHOLIPASE D; POLYUNSATURATED ALKAMIDES; RECEPTOR, CANNABINOID, CB1; TRPV CATION CHANNELS;

EID: 77649340933     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.01.001     Document Type: Article

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