-
1
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, et al.(2004) Identification of human brain tumour initiating cells. Nature 432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
-
2
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF, (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 100: 3983-3988.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
3
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE, (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
4
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE, (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
5
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, et al.(2005) Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121: 823-835.
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
Lawrence, S.4
Babar, I.5
-
6
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, et al.(2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
-
7
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick JE, (2008) Stem cell concepts renew cancer research. Blood 112: 4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
8
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen JM, Jordan CT, (2009) The increasing complexity of the cancer stem cell paradigm. Science 324: 1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
9
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G, (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
11
-
-
0034028901
-
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
-
Niwa H, Miyazaki J, Smith AG, (2000) Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 24: 372-376.
-
(2000)
Nat Genet
, vol.24
, pp. 372-376
-
-
Niwa, H.1
Miyazaki, J.2
Smith, A.G.3
-
12
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al.(2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
-
13
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers I, Colby D, Robertson M, Nichols J, Lee S, et al.(2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113: 643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
-
14
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, et al.(2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113: 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
-
15
-
-
66149167315
-
Functional evidence that the self-renewal gene NANOG regulates human tumor development
-
Jeter CR, Badeaux M, Choy G, Chandra D, Patrawala L, et al.(2009) Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells 27: 993-1005.
-
(2009)
Stem Cells
, vol.27
, pp. 993-1005
-
-
Jeter, C.R.1
Badeaux, M.2
Choy, G.3
Chandra, D.4
Patrawala, L.5
-
16
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, et al.(2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40: 499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
-
17
-
-
58949102947
-
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells
-
Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, et al.(2009) Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell 4: 129-140.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 129-140
-
-
Somervaille, T.C.1
Matheny, C.J.2
Spencer, G.J.3
Iwasaki, M.4
Rinn, J.L.5
-
18
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, et al.(2008) Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2: 333-344.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 333-344
-
-
Wong, D.J.1
Liu, H.2
Ridky, T.W.3
Cassarino, D.4
Segal, E.5
-
19
-
-
0344063368
-
Oct-3/4 is a dose-dependent oncogenic fate determinant
-
Gidekel S, Pizov G, Bergman Y, Pikarsky E, (2003) Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 4: 361-370.
-
(2003)
Cancer Cell
, vol.4
, pp. 361-370
-
-
Gidekel, S.1
Pizov, G.2
Bergman, Y.3
Pikarsky, E.4
-
20
-
-
50949166635
-
Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells
-
Chang CC, Shieh GS, Wu P, Lin CC, Shiau AL, et al.(2008) Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells. Cancer Res 68: 6281-6291.
-
(2008)
Cancer Res
, vol.68
, pp. 6281-6291
-
-
Chang, C.C.1
Shieh, G.S.2
Wu, P.3
Lin, C.C.4
Shiau, A.L.5
-
21
-
-
66149179125
-
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine
-
Knoepfler PS, (2009) Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells 27: 1050-1056.
-
(2009)
Stem Cells
, vol.27
, pp. 1050-1056
-
-
Knoepfler, P.S.1
-
22
-
-
18844392836
-
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
-
Hochedlinger K, Yamada Y, Beard C, Jaenisch R, (2005) Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121: 465-477.
-
(2005)
Cell
, vol.121
, pp. 465-477
-
-
Hochedlinger, K.1
Yamada, Y.2
Beard, C.3
Jaenisch, R.4
-
23
-
-
43949123271
-
Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men
-
Hoei-Hansen CE, (2008) Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men. Cancer Treat Rev 34: 348-367.
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 348-367
-
-
Hoei-Hansen, C.E.1
-
24
-
-
45549096807
-
Proteome profiling of breast tumors by gel electrophoresis and nanoscale electrospray ionization mass spectrometry
-
Alldridge L, Metodieva G, Greenwood C, Al-Janabi K, Thwaites L, et al.(2008) Proteome profiling of breast tumors by gel electrophoresis and nanoscale electrospray ionization mass spectrometry. J Proteome Res 7: 1458-1469.
-
(2008)
J Proteome Res
, vol.7
, pp. 1458-1469
-
-
Alldridge, L.1
Metodieva, G.2
Greenwood, C.3
Al-Janabi, K.4
Thwaites, L.5
-
25
-
-
27644473695
-
Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma
-
Ezeh UI, Turek PJ, Reijo RA, Clark AT, (2005) Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma. Cancer 104: 2255-2265.
-
(2005)
Cancer
, vol.104
, pp. 2255-2265
-
-
Ezeh, U.I.1
Turek, P.J.2
Reijo, R.A.3
Clark, A.T.4
-
26
-
-
44149108682
-
Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells
-
Ye F, Zhou C, Cheng Q, Shen J, Chen H, (2008) Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells. BMC Cancer 8: 108.
-
(2008)
BMC Cancer
, vol.8
, pp. 108
-
-
Ye, F.1
Zhou, C.2
Cheng, Q.3
Shen, J.4
Chen, H.5
-
27
-
-
48249105531
-
Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
-
Chiou SH, Yu CC, Huang CY, Lin SC, Liu CJ, et al.(2008) Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma. Clin Cancer Res 14: 4085-4095.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4085-4095
-
-
Chiou, S.H.1
Yu, C.C.2
Huang, C.Y.3
Lin, S.C.4
Liu, C.J.5
-
28
-
-
54049126940
-
Identification of a tumor-initiating stem cell population in human renal carcinomas
-
Bussolati B, Bruno S, Grange C, Ferrando U, Camussi G, (2008) Identification of a tumor-initiating stem cell population in human renal carcinomas. Faseb J 22: 3696-3705.
-
(2008)
Faseb J
, vol.22
, pp. 3696-3705
-
-
Bussolati, B.1
Bruno, S.2
Grange, C.3
Ferrando, U.4
Camussi, G.5
-
29
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang S, Balch C, Chan MW, Lai HC, Matei D, et al.(2008) Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 68: 4311-4320.
-
(2008)
Cancer Res
, vol.68
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
Lai, H.C.4
Matei, D.5
-
30
-
-
60149083711
-
Characterization of human embryonic stem cells with features of neoplastic progression
-
Werbowetski-Ogilvie TE, Bosse M, Stewart M, Schnerch A, Ramos-Mejia V, et al.(2009) Characterization of human embryonic stem cells with features of neoplastic progression. Nat Biotechnol 27: 91-97.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 91-97
-
-
Werbowetski-Ogilvie, T.E.1
Bosse, M.2
Stewart, M.3
Schnerch, A.4
Ramos-Mejia, V.5
-
31
-
-
15544388092
-
High-efficiency RNA interference in human embryonic stem cells
-
Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, et al.(2005) High-efficiency RNA interference in human embryonic stem cells. Stem Cells 23: 299-305.
-
(2005)
Stem Cells
, vol.23
, pp. 299-305
-
-
Zaehres, H.1
Lensch, M.W.2
Daheron, L.3
Stewart, S.A.4
Itskovitz-Eldor, J.5
-
32
-
-
4444243817
-
Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells
-
Matin MM, Walsh JR, Gokhale PJ, Draper JS, Bahrami AR, et al.(2004) Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells. Stem Cells 22: 659-668.
-
(2004)
Stem Cells
, vol.22
, pp. 659-668
-
-
Matin, M.M.1
Walsh, J.R.2
Gokhale, P.J.3
Draper, J.S.4
Bahrami, A.R.5
-
33
-
-
33748992563
-
Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment
-
Stewart MH, Bosse M, Chadwick K, Menendez P, Bendall SC, et al.(2006) Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nat Methods 3: 807-815.
-
(2006)
Nat Methods
, vol.3
, pp. 807-815
-
-
Stewart, M.H.1
Bosse, M.2
Chadwick, K.3
Menendez, P.4
Bendall, S.C.5
-
34
-
-
34547944403
-
Apoptosis and differentiation of human embryonic stem cells induced by sustained activation of c-Myc
-
Sumi T, Tsuneyoshi N, Nakatsuji N, Suemori H, (2007) Apoptosis and differentiation of human embryonic stem cells induced by sustained activation of c-Myc. Oncogene 26: 5564-5576.
-
(2007)
Oncogene
, vol.26
, pp. 5564-5576
-
-
Sumi, T.1
Tsuneyoshi, N.2
Nakatsuji, N.3
Suemori, H.4
-
35
-
-
21744444920
-
Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells
-
Chew JL, Loh YH, Zhang W, Chen X, Tam WL, et al.(2005) Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 25: 6031-6046.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6031-6046
-
-
Chew, J.L.1
Loh, Y.H.2
Zhang, W.3
Chen, X.4
Tam, W.L.5
-
36
-
-
21644434480
-
Transcriptional regulation of nanog by OCT4 and SOX2
-
Rodda DJ, Chew JL, Lim LH, Loh YH, Wang B, et al.(2005) Transcriptional regulation of nanog by OCT4 and SOX2. J Biol Chem 280: 24731-24737.
-
(2005)
J Biol Chem
, vol.280
, pp. 24731-24737
-
-
Rodda, D.J.1
Chew, J.L.2
Lim, L.H.3
Loh, Y.H.4
Wang, B.5
-
37
-
-
35948988905
-
The terminology of teratocarcinomas and teratomas
-
discussion 1212
-
Damjanov I, Andrews PW, (2007) The terminology of teratocarcinomas and teratomas. Nat Biotechnol 25: 1212; discussion 1212.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1212
-
-
Damjanov, I.1
Andrews, P.W.2
-
38
-
-
35948973554
-
The terminology of teratocarcinomas and teratomas
-
author reply 1211-1212
-
Lensch MW, Ince TA, (2007) The terminology of teratocarcinomas and teratomas. Nat Biotechnol 25: 1211; author reply 1211-1212.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1211
-
-
Lensch, M.W.1
Ince, T.A.2
-
39
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, et al.(2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38: 431-440.
-
(2006)
Nat Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
-
40
-
-
34848874100
-
Oct4 expression is not required for mouse somatic stem cell self-renewal
-
Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, et al.(2007) Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell 1: 403-415.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 403-415
-
-
Lengner, C.J.1
Camargo, F.D.2
Hochedlinger, K.3
Welstead, G.G.4
Zaidi, S.5
-
41
-
-
0037871588
-
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells
-
Chadwick K, Wang L, Li L, Menendez P, Murdoch B, et al.(2003) Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood 102: 906-915.
-
(2003)
Blood
, vol.102
, pp. 906-915
-
-
Chadwick, K.1
Wang, L.2
Li, L.3
Menendez, P.4
Murdoch, B.5
-
42
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, et al.(2003) A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 33: 401-406.
-
(2003)
Nat Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
-
43
-
-
0027228422
-
Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
-
Burns JC, Friedmann T, Driever W, Burrascano M, Yee JK, (1993) Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc Natl Acad Sci U S A 90: 8033-8037.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8033-8037
-
-
Burns, J.C.1
Friedmann, T.2
Driever, W.3
Burrascano, M.4
Yee, J.K.5
-
44
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|