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Volumn 9, Issue 3, 2003, Pages 123-134

Protein kinase C-eta (PKC-η) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells

Author keywords

Lipopolysaccharide; Monocytes macrophages; Nitric oxide; PKC eta

Indexed keywords

ENDOTOXIN; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE; NITRIC OXIDE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA1; PROTEIN KINASE C BETA2; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA; PROTEIN KINASE C GAMMA; PROTEIN KINASE C IOTA; PROTEIN KINASE C MU; PROTEIN KINASE C THETA; PROTEIN KINASE C ZETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0346496404     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2003.09.006     Document Type: Article
Times cited : (29)

References (51)
  • 1
    • 0030923095 scopus 로고    scopus 로고
    • Intracellular signal modulation: A pivotal role for protein kinase C
    • Casabona G. Intracellular signal modulation: a pivotal role for protein kinase C. Prog. Neuro-Pshychopharmacol. Biol. Pshychial. 21:1997;407-425.
    • (1997) Prog. Neuro-Pshychopharmacol. Biol. Pshychial. , vol.21 , pp. 407-425
    • Casabona, G.1
  • 2
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumour promotion
    • Nishizuk Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature (London). 308:1984;693-698.
    • (1984) Nature (London) , vol.308 , pp. 693-698
    • Nishizuk, Y.1
  • 5
    • 0028935273 scopus 로고
    • Nitric oxide, novel biology with clinical relevance
    • Billiar T.R. Nitric oxide, novel biology with clinical relevance. Ann. Surg. 221:1995;339-349.
    • (1995) Ann. Surg. , vol.221 , pp. 339-349
    • Billiar, T.R.1
  • 6
    • 0033559903 scopus 로고    scopus 로고
    • Over-expression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: Involvement of c-Jun N-Terminal kinase/stress-activated protein kinase, p38 kinase, and CPP protease pathways
    • Jun C.-D., Oh C.D., Kwak H.-J., Pae H.-O., Yoo J.-C., Choi B.-M., Chun J.-S., Park H.-O., Chung H.-T. Over-expression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-Terminal kinase/stress-activated protein kinase, p38 kinase, and CPP protease pathways. J. Immunol. 162:1999;3395-3401.
    • (1999) J. Immunol. , vol.162 , pp. 3395-3401
    • Jun, C.-D.1    Oh, C.D.2    Kwak, H.-J.3    Pae, H.-O.4    Yoo, J.-C.5    Choi, B.-M.6    Chun, J.-S.7    Park, H.-O.8    Chung, H.-T.9
  • 7
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • Nathan C., Hibbs J.B. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3:1991;65-70.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 65-70
    • Nathan, C.1    Hibbs, J.B.2
  • 9
    • 0027258651 scopus 로고
    • Evidence for an antiviral effect of nitric oxide. Inhibition of Herpes Simplex Virus Type 1 Replication
    • Croen K.D. Evidence for an antiviral effect of nitric oxide. Inhibition of Herpes Simplex Virus Type 1 Replication. J. Clin. Invest. 91:1993;2446-2552.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2446-2552
    • Croen, K.D.1
  • 10
    • 0027488067 scopus 로고
    • Inhibition of viral replication by interferon-γ-induced nitric oxide synthase
    • Karupiah G., Xie Q.-w., Buller R.M.L., Nathan C., Duart C., MacMiking J.D. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science. 261:1993;1445-1448.
    • (1993) Science , vol.261 , pp. 1445-1448
    • Karupiah, G.1    Xie, Q.W.2    Buller, R.M.L.3    Nathan, C.4    Duart, C.5    MacMiking, J.D.6
  • 11
    • 0028293049 scopus 로고
    • Expression of inducible nitric oxide synthase by stimulated macrophages correlates with their anti-histoplasma activity
    • Lane T.E., Otero G.C., Wu-Hsich B.A., Howard D.H. Expression of inducible nitric oxide synthase by stimulated macrophages correlates with their anti-histoplasma activity. Infect. Immunol. 62:1994;1478-1489.
    • (1994) Infect. Immunol. , vol.62 , pp. 1478-1489
    • Lane, T.E.1    Otero, G.C.2    Wu-Hsich, B.A.3    Howard, D.H.4
  • 12
    • 0026062981 scopus 로고
    • Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages
    • Liew F.Y., Li Y., Parkinson C., Rogers M.V., Moncada S. Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages. Eur. J. Immunol. 21:1991;3009-3014.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 3009-3014
    • Liew, F.Y.1    Li, Y.2    Parkinson, C.3    Rogers, M.V.4    Moncada, S.5
  • 14
    • 0032930126 scopus 로고    scopus 로고
    • Rate and severity of HIV-associated dementia (HAD): Correlations with Gp41 and iNOS
    • Adamson D.C., McArthur J.C., Dawson T.M., Dawson V.L. Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS. Mol. Med. 5:1999;98-109.
    • (1999) Mol. Med. , vol.5 , pp. 98-109
    • Adamson, D.C.1    McArthur, J.C.2    Dawson, T.M.3    Dawson, V.L.4
  • 15
    • 0033559312 scopus 로고    scopus 로고
    • Human immuno-deficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: Astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome
    • Hori K., Burd P.R., Furuke K., Kutza J., Weih K.A., Clouse K.A. Human immuno-deficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome. Blood. 93(6):1999;1843-1850.
    • (1999) Blood , vol.93 , Issue.6 , pp. 1843-1850
    • Hori, K.1    Burd, P.R.2    Furuke, K.3    Kutza, J.4    Weih, K.A.5    Clouse, K.A.6
  • 17
    • 0031754714 scopus 로고    scopus 로고
    • Increased production of NO stimulated by IL-1β in peripheral blood mononuclear cells in patients with systemic sclerosis
    • Yamamoto T., Sawada Y., Katayama I., Nishioka Y. Increased production of NO stimulated by IL-1β in peripheral blood mononuclear cells in patients with systemic sclerosis. Br. J. Rheumatol. 37:1998;1123-1125.
    • (1998) Br. J. Rheumatol. , vol.37 , pp. 1123-1125
    • Yamamoto, T.1    Sawada, Y.2    Katayama, I.3    Nishioka, Y.4
  • 18
    • 0026019071 scopus 로고
    • Characterization and differential distribution of the three major human protein kinase C isozymes (PKC-α, PKC-β, PKC-γ) of the central nervous system in normal and Alzheimer's disease brains
    • Clark E.A., Leach K.L., Trojanowski J.Q., Y-Lee M.V. Characterization and differential distribution of the three major human protein kinase C isozymes (PKC-α, PKC-β, PKC-γ) of the central nervous system in normal and Alzheimer's disease brains. Lab. Invest. 64:1991;35-44.
    • (1991) Lab. Invest. , vol.64 , pp. 35-44
    • Clark, E.A.1    Leach, K.L.2    Trojanowski, J.Q.3    Y-Lee, M.V.4
  • 19
    • 0027285626 scopus 로고    scopus 로고
    • Exogenous nitric oxide (NO). Generation of IL-1β induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyal-3-phosphate dehydrogenase in RIN m5F cells
    • Dimmeler S., Ankarcrona M., Nicotera P., Brune B. Exogenous nitric oxide (NO). Generation of IL-1β induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyal-3-phosphate dehydrogenase in RIN m5F cells. J. Immunol. 150:1997;2964-2971.
    • (1997) J. Immunol. , vol.150 , pp. 2964-2971
    • Dimmeler, S.1    Ankarcrona, M.2    Nicotera, P.3    Brune, B.4
  • 20
    • 0026549480 scopus 로고
    • Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediate produced by activated murine macrophages
    • Chang J., Xing Y., Magliozzo R.S., Bloom B.R. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediate produced by activated murine macrophages. J. Exp. Med. 175:1992;1111-1122.
    • (1992) J. Exp. Med. , vol.175 , pp. 1111-1122
    • Chang, J.1    Xing, Y.2    Magliozzo, R.S.3    Bloom, B.R.4
  • 21
    • 0029133539 scopus 로고
    • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages
    • Weinberg J.B., Misukonis M.A., Mason S.N., Sauls D.L., Dittman W.A., Wood E.R., Smith G.K., McDonald B., Bachus K.E., Haney A.F., Granger D.L. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood. 86:1995;1184-1195.
    • (1995) Blood , vol.86 , pp. 1184-1195
    • Weinberg, J.B.1    Misukonis, M.A.2    Mason, S.N.3    Sauls, D.L.4    Dittman, W.A.5    Wood, E.R.6    Smith, G.K.7    McDonald, B.8    Bachus, K.E.9    Haney, A.F.10    Granger, D.L.11
  • 22
    • 0026691581 scopus 로고
    • Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and IFN-γ trough a nitric-oxide dependent mechanism
    • Munoz-Fernandez M.A., Fernandez M.A., Fresno M. Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and IFN-γ trough a nitric-oxide dependent mechanism. Immunol. Lett. 33:1992;35-40.
    • (1992) Immunol. Lett. , vol.33 , pp. 35-40
    • Munoz-Fernandez, M.A.1    Fernandez, M.A.2    Fresno, M.3
  • 23
    • 0027979731 scopus 로고
    • Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide
    • Zemabala M., Siedlar M., Marcinkiewicz J., Pryjma J. Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide. Eur. J. Immunol. 24:1994;435-439.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 435-439
    • Zemabala, M.1    Siedlar, M.2    Marcinkiewicz, J.3    Pryjma, J.4
  • 24
    • 0032762414 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitric oxide production in Leishmania infantum-infected human macrophages stimulated with interferon-gamma and bacterial lipopolysaccharide
    • Panaro M.A., Acquafredda A., Lisi S., Lofrumento D.D., Trotta T., Satalino R., Saccia M., Mitolo V., Brandonisio O. Inducible nitric oxide synthase and nitric oxide production in Leishmania infantum-infected human macrophages stimulated with interferon-gamma and bacterial lipopolysaccharide. Int. J. Clin. Lab. Res. 29(3):1999;122-127.
    • (1999) Int. J. Clin. Lab. Res. , vol.29 , Issue.3 , pp. 122-127
    • Panaro, M.A.1    Acquafredda, A.2    Lisi, S.3    Lofrumento, D.D.4    Trotta, T.5    Satalino, R.6    Saccia, M.7    Mitolo, V.8    Brandonisio, O.9
  • 25
    • 0028010766 scopus 로고
    • Gp120 HIV envelope glycoprotein increases the production of NO in human monocyte-derived macrophages
    • Pietraforte D., ritarelli E., Testa U., Minetti M. gp120 HIV envelope glycoprotein increases the production of NO in human monocyte-derived macrophages. J. Leukoc. Biol. 55:1994;175-182.
    • (1994) J. Leukoc. Biol. , vol.55 , pp. 175-182
    • Pietraforte, D.1    Ritarelli, E.2    Testa, U.3    Minetti, M.4
  • 26
  • 27
    • 0028299497 scopus 로고
    • Properties of protein kinase C isoforms (βII, ε, and ξ) in a macrophage cell line (J774) and their roles in LPS-induced nitric oxide production
    • Fujihara M., Connolly N., Ito N., Suzuki T. Properties of protein kinase C isoforms (βII, ε, and ξ) in a macrophage cell line (J774) and their roles in LPS-induced nitric oxide production. J. Immunol. 152:1994;1898-2006.
    • (1994) J. Immunol. , vol.152 , pp. 1898-2006
    • Fujihara, M.1    Connolly, N.2    Ito, N.3    Suzuki, T.4
  • 28
    • 0032484218 scopus 로고    scopus 로고
    • Protein kinase C-α modulates lipopolysaccharide-induced functions in a murine macrophage cell line
    • St-Denis A., Chano F., Pierre T., St-Pierre Y., Descoteaux A. Protein kinase C-α modulates lipopolysaccharide-induced functions in a murine macrophage cell line. J. Biol. Chem. 273(49):1998;32787-32792.
    • (1998) J. Biol. Chem. , vol.273 , Issue.49 , pp. 32787-32792
    • St-Denis, A.1    Chano, F.2    Pierre, T.3    St-Pierre, Y.4    Descoteaux, A.5
  • 29
    • 0032584724 scopus 로고    scopus 로고
    • Protein kinase C-η mediates lipopolysaccharide-induced nitric-oxide synthase expression in primary astrocytes
    • Chen C.-C., Wang J.-K., Chen W.-C., Lin S.-B. Protein kinase C-η mediates lipopolysaccharide-induced nitric-oxide synthase expression in primary astrocytes. J. Biol. Chem. 273(31):1998;19424-19430.
    • (1998) J. Biol. Chem. , vol.273 , Issue.31 , pp. 19424-19430
    • Chen, C.-C.1    Wang, J.-K.2    Chen, W.-C.3    Lin, S.-B.4
  • 30
    • 0029730637 scopus 로고    scopus 로고
    • Up-regulation of protein kinase C-ε promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7
    • Diaz-Guerra M.J.M., Bodelon O.G., Velasco M., Whelan R., Parker P., Bosca L. Up-regulation of protein kinase C-ε promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7. J. Biol. Chem. 271(50):1996;32028-32033.
    • (1996) J. Biol. Chem. , vol.271 , Issue.50 , pp. 32028-32033
    • Diaz-Guerra, M.J.M.1    Bodelon, O.G.2    Velasco, M.3    Whelan, R.4    Parker, P.5    Bosca, L.6
  • 31
    • 0031817189 scopus 로고    scopus 로고
    • Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes
    • Monick M.M., Carter A.B., Gudmundsson G., Geist L.J., Hunninghake G.W. Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes. Am. J. Physiol. 275(2Pt1):1998;L389-L397.
    • (1998) Am. J. Physiol. , vol.275 , Issue.2 PART 1
    • Monick, M.M.1    Carter, A.B.2    Gudmundsson, G.3    Geist, L.J.4    Hunninghake, G.W.5
  • 34
    • 0027937121 scopus 로고
    • Nitric oxide synthase: MRNA expression of different isoforms in human monocytes/macrophages
    • Reiling N., Ulmer A.J., Duchrow M., Ernst M., Flad H.D., Hauschildt S. Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages. Eur. J. Immunol. 24:1994;1941-1944.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1941-1944
    • Reiling, N.1    Ulmer, A.J.2    Duchrow, M.3    Ernst, M.4    Flad, H.D.5    Hauschildt, S.6
  • 35
    • 0026451081 scopus 로고
    • Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y. Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 36
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumour promotion
    • Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature (London). 308:1984;693-698.
    • (1984) Nature (London) , vol.308 , pp. 693-698
    • Nishizuka, Y.1
  • 37
    • 0027459588 scopus 로고
    • Expression of the nitric oxide synthase gene in mouse macrophages activated for tumour cell killing: Molecular basis for the synergy between interferone-γ and lipopolysaccharide
    • Lorsbach R.B., Murphy W.J., Lowenstein C.J., Snyder S.H., Russell S.W. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumour cell killing: Molecular basis for the synergy between interferone-γ and lipopolysaccharide. J. Biol. Chem. 268:1993;908-1913.
    • (1993) J. Biol. Chem. , vol.268 , pp. 908-1913
    • Lorsbach, R.B.1    Murphy, W.J.2    Lowenstein, C.J.3    Snyder, S.H.4    Russell, S.W.5
  • 39
    • 0029618106 scopus 로고
    • Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer
    • Tzeng E., Billiar T.R., Robbins P.D., Loftus M., Stuehr D.J. Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer. Proc. Natl. Acad. Sci. USA. 92(25):1995;11771-11775.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , Issue.25 , pp. 11771-11775
    • Tzeng, E.1    Billiar, T.R.2    Robbins, P.D.3    Loftus, M.4    Stuehr, D.J.5
  • 40
    • 0032926256 scopus 로고    scopus 로고
    • Expression of the inducible NO synthase in human and monocytic U937 cells allows high output nitric oxide production
    • Bertholet S., Tzeng E., Felley-Bosco E., Manuel J. Expression of the inducible NO synthase in human and monocytic U937 cells allows high output nitric oxide production. J. Leukoc. Biol. 65:1999;50-58.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 50-58
    • Bertholet, S.1    Tzeng, E.2    Felley-Bosco, E.3    Manuel, J.4
  • 41
    • 0030845531 scopus 로고    scopus 로고
    • Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells
    • Yan L., Wang S., Rafferty S.P., Wesley R.A., Danner R.L. Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells. Blood. 90:1997;1160-1167.
    • (1997) Blood , vol.90 , pp. 1160-1167
    • Yan, L.1    Wang, S.2    Rafferty, S.P.3    Wesley, R.A.4    Danner, R.L.5
  • 42
    • 0033958945 scopus 로고    scopus 로고
    • Human and monocytic U937 cells transfected with human hepatic inducible nitric oxide synthase exhibit leishmanicidal activity
    • Bertholet S., Manuel J. Human and monocytic U937 cells transfected with human hepatic inducible nitric oxide synthase exhibit leishmanicidal activity. J. Leukoc. Biol. 67:2000;34-39.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 34-39
    • Bertholet, S.1    Manuel, J.2
  • 43
    • 0029985232 scopus 로고    scopus 로고
    • Nitric oxide production in cells derived from the human joint
    • Grabowski P.S., Macpherson H., Ratston S.H. Nitric oxide production in cells derived from the human joint. Br. J. Rheumatol. 35:1996;207-212.
    • (1996) Br. J. Rheumatol. , vol.35 , pp. 207-212
    • Grabowski, P.S.1    MacPherson, H.2    Ratston, S.H.3
  • 46
    • 0027948094 scopus 로고    scopus 로고
    • Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors
    • De Maria R., Caffein M.G., Trotta R., Hippo M.R., Festuca C., Sandon A., Test R. Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. J. Exp. Med. 180:1998;1999-2004.
    • (1998) J. Exp. Med. , vol.180 , pp. 1999-2004
    • De Maria, R.1    Caffein, M.G.2    Trotta, R.3    Hippo, M.R.4    Festuca, C.5    Sandon, A.6    Test, R.7
  • 47
    • 0027416708 scopus 로고
    • Regulation of CD69 expression on human killer cells: Differential involvement of protein kinase C and protein tyrosine kinases
    • Borrego F., Pena J., Solana R. Regulation of CD69 expression on human killer cells: differential involvement of protein kinase C and protein tyrosine kinases. Eur. J. Immunol. 23:1993;1039-1043.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1039-1043
    • Borrego, F.1    Pena, J.2    Solana, R.3
  • 48
    • 0028791708 scopus 로고
    • Nitric oxide production by human monocytes: Evidence for a role of CD23
    • Dugas B., Masala M.D., Damans C., Kalb J.P. Nitric oxide production by human monocytes: evidence for a role of CD23. Immunol. Today. 16:1995;574-580.
    • (1995) Immunol. Today , vol.16 , pp. 574-580
    • Dugas, B.1    Masala, M.D.2    Damans, C.3    Kalb, J.P.4
  • 49
    • 0032403566 scopus 로고    scopus 로고
    • Antisense oligonucleotides targeting PKC-α, -β1, -δ, but not -η Inhibit lipopolysaccharide-induced nitric oxide synthase expression in Raw 264.7 macrophages involvement of a nuclear factor-κB dependent mechanism
    • Chen C.-C., Wang J.-K., Lin S.-B. Antisense oligonucleotides targeting PKC-α, -β1, -δ, but not -η inhibit lipopolysaccharide- induced nitric oxide synthase expression in Raw 264.7 macrophages involvement of a nuclear factor-κB dependent mechanism. J. Immunol. 161:1998;6206-6214.
    • (1998) J. Immunol. , vol.161 , pp. 6206-6214
    • Chen, C.-C.1    Wang, J.-K.2    Lin, S.-B.3
  • 51
    • 0029886747 scopus 로고    scopus 로고
    • Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon-γ
    • Zhang X., Laubach E.V., Alley E.W., Edwards A.K., Sherman A.P., Russel W.S., Murphy J.W. Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon-γ J. Leukoc. Biol. 59:1996;575-585.
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 575-585
    • Zhang, X.1    Laubach, E.V.2    Alley, E.W.3    Edwards, A.K.4    Sherman, A.P.5    Russel, W.S.6    Murphy, J.W.7


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