Roles of lysophosphatidic acid and the Rho-associated kinase pathway in the migration of dental pulp cells

Experimental Cell Research

Volumn 316, Issue 6, 2010, Pages 1019-1027

  Cheng, Ran ^a   Cheng, Li ^a   Shao, Mei ying ^a   Yang, Hui ^a   Wang, Feng ming ^a   Hu, Tao ^a   Zhou, Xue dong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cell migration; Dental pulp cells; LPA; ROCK

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA SMOOTH MUSCLE ACTIN; LYSOPHOSPHATIDIC ACID; RAC PROTEIN; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; SMALL INTERFERING RNA;

ACTIN POLYMERIZATION; ADULT; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; LAMELLIPODIUM; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOOTH PULP;

EID: 77649192038     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.01.002     Document Type: Article

References (46)

1. Smith A.J., and Lesot H. Induction and regulation of crown dentinogenesis: embryonic events as a template for dental tissue repair?. Crit. Rev. Oral Biol. Med. 12 (2001) 425-437
2. Moolenaar W.H. Lysophosphatidic acid, a multifunctional phospholipid messenger. J. Biol. Chem. 270 (1995) 12949-12952
3. Eichholtz T., Jalink K., Fahrenfort I., and Moolenaar W.H. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem. J. 291 (1993) 677-680
4. Lee H., Goetzl E.J., and An S. Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. Am. J. Physiol. Cell Physiol. 278 (2000) C612-C618
5. van Leeuwen F.N., Giepmans B.N., van Meeteren L.A., and Moolenaar W.H. Lysophosphatidic acid: mitogen and motility factor. Biochem. Soc. Trans. 31 (2003) 1209-1212
6. Hama K., Aoki J., Fukaya M., Kishi Y., Sakai T., Suzuki R., Ohta H., Yamori T., Watanabe M., Chun J., and Arai H. Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J. Biol. Chem. 279 (2004) 17634-17639
7. Yamada T., Sato K., Komachi M., Malchinkhuu E., Tobo M., Kimura T., Kuwabara A., Yanagita Y., Ikeya T., Tanahashi Y., Ogawa T., Ohwada S., Morishita Y., Ohta H., Im D.S., Tamoto K., Tomura H., and Okajima F. Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1. J. Biol. Chem. 279 (2004) 6595-6605
8. Sturm A., Sudermann T., Schulte K.M., Goebell H., and Dignass A.U. Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid. Gastroenterology 117 (1999) 368-377
9. Ridley A.J. Rho GTPases and cell migration. J. Cell. Sci. 11 (2001) 2713-2722
10. Hall A. Rho GTPases and the actin cytoskeleton. Science 279 (1998) 509-514
11. Raftopoulou M., and Hall A. Cell migration: Rho GTPases lead the way. Dev. Biol. 265 (2004) 23-32
12. Bi D., Nishimura J., Niiro N., Hirano K., and Kanaide H. Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility. Circ. Res. 6 (2005) 890-897
13. Worthylake R.A., Lemoine S., Watson J.M., and Burridge K. RhoA is required for monocyte tail retraction during transendothelial migration. J. Cell Biol. 154 (2001) 147-160
14. Buhl A.M., Johnson N.L., Dhanasekaran N., and Johnson G.L. G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly. J. Biol. Chem. 270 (1995) 24631-24634
15. Fukuhara S., Murga C., Zohar M., Igishi T., and Gutkind J.S. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. J. Biol. Chem. 274 (1999) 5868-5879
16. Yuan J., Slice L.W., Gu J., and Rozengurt E. Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid. J. Biol. Chem. 278 (2003) 4882-4891
17. Dutt P., Nguyen N., and Toksoz D. Role of Lbc RhoGEF in Galpha12/13-induced signals to Rho GTPase. Cell Signal. 16 (2004) 201-209
18. Riento K., and Ridley A.J. ROCKS: multifunctional kinases in cell behavior. Nat. Rev. Mol. Cell Biol. 4 (2003) 446-456
19. Sumi T., Matsumoto K., and Nakamura T. Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase. J. Biol. Chem. 276 (2001) 670-676
20. Kawano Y., Fukata Y., Oshiro N., Amano M., Nakamura T., Ito M., Matsumura F., Inagaki M., and Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J. Cell Biol. 147 (1999) 1023-1038
21. Mitchison T.J., and Cramer L.P. Actin-based cell motility and cell locomotion. Cell 84 (1996) 371-379
22. Council for International Organizations of Medical Sciences (CIOMS). International Ethical Guidelines for Biomedical Research Involving Human Subjects, World Health Organization (2002) Geneva
23. Wang F.M., Hu T., TanH H., and Zhou X.D. p38 Mitogen-activated protein kinase affects transforming growth factor-beta/Smad signaling in human dental pulp cells. Mol. Cell. Biochem. 291 (2006) 49-54
24. Nakagawa O., Fujisawa K., Ishizaki T., Saito Y., Nakao K., and Narumiya S. ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett. 392 (1996) 89-193
25. Machesky L.M., and Schliwa M. Cell dynamics: a new look at the cytoskeleton. Nat. Cell Biol. 2 (2000) E17-E18
26. Katoh K., Kano Y., Amano M., Kaibuchi K., and Fujiwara K. Stress fi{ligature}ber organization regulated by MLCK and Rho-kinase in cultured human fi{ligature}broblast. Am. J. Cell Physiol. 280 (2001) C1669-C1679
27. Katoh K., Kano Y., and Ookawara S. Rho-kinase dependent organization of stress fibers and focal adhesions in cultured fibroblasts. Genes Cells 12 (2007) 623-638
28. Dugina V., Alexandrova A., Chaponnier C., Vasiliev J., and Gabbiani G. Rat fibroblasts cultured from various organs exhibit differences in α-smooth muscle actin expression, cytoskeletal pattern, and adhesive structure organization. Exp. Cell Res. 238 (1998) 481-490
29. Kolyada A.Y., Riley K.N., and Herman I.M. Rho GTPase signalling modulates cell shape and contractile phenotype in an isoactin-specifi{ligature}c manner. Am. J. Physiol. Cell Physiol. 285 (2003) C1116-C1121
30. Worth NF N.F., Campbell G.R., Campbell J.H., and Rolfe B.E. Rho expression and activation in vascular smooth muscle cells. Cell Motil. Cytoskeleton 59 (2004) 189-200
31. Brock D.P., Marty-Roix R., and Spector M. Alpha-smooth-muscle actin in and contraction of porcine dental pulp cells. J. Dent. Res. 81 (2002) 203-208
32. Miura M., Gronthos S., Zhao M., Lu B., Fisher L.W., Robey P.G., and Shi S. SHED: stem cells from human exfoliated deciduous teeth. Proc. Natl. Acad. Sci. 100 (2003) 5807-5812
33. Shi S., and Gronthos S. Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J. Bone Miner. Res. 18 (2003) 696-704
34. Salhia B., Rutten F., Nakada M., Beaudry C., Berens M., Kwan A., and Rutka J.T. Inhibition of Rho-Kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1. Cancer Res. 65 (2005) 8792-8800
35. Farges J.C., Romeas A., Melin M., Pin J.J., Lebecque S., Lucchini M., Bleicher F., and Magloire H. TGF-beta 1 induces accumulation of dendritic cells in the odontoblast layer. J. Dent. Res. 82 (2003) 652-656
36. van Leeuwen F.N., Olivo C., Grivell S., Giepmans B.N., Collard J.G., and Moolenaar W.H. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1. J. Biol. Chem. 278 (2003) 400-406
37. Gruber R., Kandler B., Jindra C., Watzak G., and Watzek G. Dental pulp fibroblasts contain target cells for lysophosphatidic acid. J. Dent. Res. 83 (2004) 491-495
38. Koga T., Awai M., Tsutsui J., Yue B.Y., and Tanihara H. Rho-associated protein kinase inhibitor, Y-27632, induces alterations in adhesion, contraction and motility in cultured human trabecular meshwork cells. Exp. Eye Res. 82 (2006) 362-370
39. Narumiya S., Tanji M., and Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev. 28 (2009) 65-76
40. Ortíz-López L., Morales-Mulia S., Ramírez-Rodríguez G., and Benítez-King G. ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration. J. Pineal Res. 46 (2009) 15-21
41. Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., and Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147 (1999) 1009-1022
42. Tsuji T., Ishizaki T., Okamoto M., Higashida C., Kimura K., Furuyashiki T., Arakawa Y., Birge R.B., Nakamoto T., Hirai H., and Narumiya S. ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J. Cell Biol. 57 (2002) 819-830
43. Sagot I., Klee S.K., and Pellman D. Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat. Cell Biol. 4 (2002) 42-50
44. Higashida C., Miyoshi T., Fujita A., Oceguera-Yanez F., Monypenny J., Andou Y., Narumiya S., and Watanabe N. Actin polymerization-driven molecular movement of mDia1 in living cells. Science 303 (2004) 2007-2010
45. Schwartz M. Rho signalling at a glance. J. Cell. Sci. 117 (2004) 5457-5478
46. Yamana N., Arakawa Y., Nishino T., Kurokawa K., Tanji M., Itoh R.E., Monypenny J., Ishizaki T., Bito H., Nozaki K., Hashimoto N., Matsuda M., and Narumiya S. Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol. Cell. Biol. 26 (2006) 6844-6858