Blockade of LTB4-induced chemotaxis by bioactive molecules interfering with the BLT2-Gαi interaction

Biochemical Pharmacology

Volumn 79, Issue 10, 2010, Pages 1506-1515

  Kim, Joo Young ^a   Lee, Won Kyu ^b   Yu, Yeon Gyu ^b   Kim, Jae Hong ^a  

^a Korea University   (South Korea)

^b Kookmin University   (South Korea)

Author keywords

BLT2; Chemotaxis; Chloranil; LTB4; Purpurin

Indexed keywords

CHLORANIL; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA; LEUKOTRIENE B4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BLT2; PROTEIN KINASE B; PURPURIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTHRAQUINONE DERIVATIVE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LEUKOTRIENE B4 RECEPTOR;

ANIMAL CELL; ARTICLE; CHEMOTAXIS; CHO CELL; CONTROLLED STUDY; DRUG APPROVAL; DRUG MECHANISM; DRUG SCREENING; ENZYME PHOSPHORYLATION; HIGH THROUGHPUT SCREENING; IC 50; INFLAMMATION; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL SURVIVAL; CRICETULUS; DRUG ANTAGONISM; DRUG EFFECT; HAMSTER; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SURFACE PLASMON RESONANCE;

ANIMALS; ANTHRAQUINONES; CELL SURVIVAL; CHEMOTAXIS; CHLORANIL; CHO CELLS; CRICETINAE; CRICETULUS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; IMMUNOBLOTTING; RAC1 GTP-BINDING PROTEIN; RECEPTORS, LEUKOTRIENE B4; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

EID: 77649190043     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.01.018     Document Type: Article

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