Nuclear size measurement is a simple method for the assessment of hepatocellular aging in non-alcoholic fatty liver disease: Comparison with telomere-specific quantitative FISH and p21 immunohistochemistry

Pathology International

Volumn 60, Issue 3, 2010, Pages 175-183

  Nakajima, Tomoki ^a   Nakashima, Toshiaki ^a   Okada, Yoshihisa ^b   Jo, Masayasu ^b   Nishikawa, Taichiro ^b   Mitsumoto, Yasuhide ^b   Katagishi, Tatsuo ^b   Kimura, Hiroyuki ^b   Itoh, Yoshito ^b   Kagawa, Keizo ^c   Yoshikawa, Toshikazu ^a  

^a Saiseikai Kyoto Hospital   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c Fukuchiyama City Hospital   (Japan)

Author keywords

Non alcoholic fatty liver disease; Nuclear enlargement; P21 protein; Quantitative fluorescent in situ hybridization; Senescence; Telomere

Indexed keywords

ALANINE AMINOTRANSFERASE; KI 67 ANTIGEN; PROTEIN P21;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CELL AGING; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL; LIVER CELL DAMAGE; LIVER REGENERATION; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; NUCLEAR SIZE; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TELOMERE; UPREGULATION;

ADULT; CELL AGING; CELL NUCLEUS; CELL NUCLEUS SIZE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FATTY LIVER; FEMALE; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LIVER; MALE; STATISTICS, NONPARAMETRIC; TELOMERE;

EID: 77649171804     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2009.02504.x     Document Type: Article

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