-
1
-
-
0026517010
-
Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer C, Krey G, Keller H et al.: Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68, 879-887 (1992).
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
-
2
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20, 649-688 (1999).
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
3
-
-
0029102676
-
Structural organization of mouse peroxisome proliferator-activated receptor γ(mPPAR γ) gene: Alternative promoter use and different splicing yield two mPPAR γisoforms
-
Zhu Y, Qi C, Korenberg JR et al.: Structural organization of mouse peroxisome proliferator-activated receptor γ(mPPAR γ) gene: alternative promoter use and different splicing yield two mPPAR γisoforms. Proc. Natl Acad. Sci. USA 92, 7921-7925 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7921-7925
-
-
Zhu, Y.1
Qi, C.2
Korenberg, J.R.3
-
4
-
-
0037330414
-
PPARγ agonists in the treatment of Type II diabetes: Is increased fatness commensurate with long-term efficacy?
-
Larsen TM, Toubro S, Astrup A: PPARγ agonists in the treatment of Type II diabetes: is increased fatness commensurate with long-term efficacy? Int. J. Obes. Relat. Metab. Disord. 27, 147-161 (2003).
-
(2003)
Int. J. Obes. Relat. Metab. Disord.
, vol.27
, pp. 147-161
-
-
Larsen, T.M.1
Toubro, S.2
Astrup, A.3
-
5
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
-
Ferre P: The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53(Suppl. 1), S43-S50 (2004).
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Ferre, P.1
-
6
-
-
22144477527
-
Anandamide induced PPARγ transcriptional activation and 3T3-L1 preadipocyte differentiation
-
Bouaboula M, Hilairet S, Marchand J et al.: Anandamide induced PPARγ transcriptional activation and 3T3-L1 preadipocyte differentiation. Eur. J. Pharmacol. 517, 174-181 (2005).
-
(2005)
Eur. J. Pharmacol.
, vol.517
, pp. 174-181
-
-
Bouaboula, M.1
Hilairet, S.2
Marchand, J.3
-
7
-
-
58849102970
-
Posttranslational modifications of PPAR-γ: Fine-tuning the metabolic master regulator
-
Beekum O, Fleskens V, Kalkhoven E: Posttranslational modifications of PPAR-γ: fine-tuning the metabolic master regulator. Obesity (Silver Spring) 17, 213-219 (2009).
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 213-219
-
-
Beekum, O.1
Fleskens, V.2
Kalkhoven, E.3
-
8
-
-
14544272384
-
Phosphorylation of PPARs: From molecular characterization to physiological relevance
-
Diradourian C, Girard J, Pegorier JP: Phosphorylation of PPARs: from molecular characterization to physiological relevance. Biochimie 87, 33-38 (2005).
-
(2005)
Biochimie
, vol.87
, pp. 33-38
-
-
Diradourian, C.1
Girard, J.2
Pegorier, J.P.3
-
9
-
-
34547731515
-
Nuclear receptor coregulators and human disease
-
Lonard DM, Lanz RB, O'Malley BW: Nuclear receptor coregulators and human disease. Endocr. Rev. 28, 575-587 (2007).
-
(2007)
Endocr. Rev.
, vol.28
, pp. 575-587
-
-
Lonard, D.M.1
Lanz, R.B.2
O'Malley, B.W.3
-
10
-
-
34548252291
-
Nuclear receptor coregulators: Judges, juries, and executioners of cellular regulation
-
Lonard DM, O'Malley BW: Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol. Cell 27, 691-700 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 691-700
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
11
-
-
25444455856
-
Dynamic combinatorial networks in nuclear receptor-mediated transcription
-
Rochette-Egly C: Dynamic combinatorial networks in nuclear receptor-mediated transcription. J. Biol. Chem. 280, 32565-32568 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32565-32568
-
-
Rochette-Egly, C.1
-
12
-
-
34249727164
-
Transcriptional coregulators in the control of energy homeostasis
-
Feige JN, Auwerx J: Transcriptional coregulators in the control of energy homeostasis. Trends Cell. Biol. 17, 292-301 (2007).
-
(2007)
Trends Cell. Biol.
, vol.17
, pp. 292-301
-
-
Feige, J.N.1
Auwerx, J.2
-
14
-
-
12144291563
-
Peroxisome proliferator-activated receptor γis required in mature white and brown adipocytes for their survival in the mouse
-
Imai T, Takakuwa R, Marchand S et al.: Peroxisome proliferator-activated receptor γis required in mature white and brown adipocytes for their survival in the mouse. Proc. Natl Acad. Sci. USA 101, 4543-4547 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 4543-4547
-
-
Imai, T.1
Takakuwa, R.2
Marchand, S.3
-
15
-
-
0034970334
-
The roles of PPARs in adipocyte differentiation
-
Grimaldi PA: The roles of PPARs in adipocyte differentiation. Prog. Lipid Res. 40, 269-281 (2001).
-
(2001)
Prog. Lipid Res.
, vol.40
, pp. 269-281
-
-
Grimaldi, P.A.1
-
17
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARγ
-
Tontonoz P, Spiegelman BM: Fat and beyond: the diverse biology of PPARγ. Annu. Rev. Biochem. 77, 289-312 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
18
-
-
33748937223
-
Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance
-
Agostini M, Schoenmakers E, Mitchell C et al.: Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance. Cell. Metab. 4, 303-311 (2006).
-
(2006)
Cell. Metab.
, vol.4
, pp. 303-311
-
-
Agostini, M.1
Schoenmakers, E.2
Mitchell, C.3
-
19
-
-
0033599038
-
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VE et al.: Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402, 880-883 (1999).
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
-
20
-
-
18644382993
-
Digenic inheritance of severe insulin resistance in a human pedigree
-
Savage DB, Agostini M, Barroso I et al.: Digenic inheritance of severe insulin resistance in a human pedigree. Nat. Genet. 31, 379-384 (2002).
-
(2002)
Nat. Genet.
, vol.31
, pp. 379-384
-
-
Savage, D.B.1
Agostini, M.2
Barroso, I.3
-
21
-
-
0033213631
-
PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P, Troy AE et al.: PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell 4, 611-617 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
-
22
-
-
0033213637
-
PPAR γ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES et al.: PPAR 7gamma; is required for placental, cardiac, and adipose tissue development. Mol. Cell 4, 585-595 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
-
23
-
-
0033212964
-
PPAR γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota N, Terauchi Y, Miki H et al.: PPAR γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell 4, 597-609 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
-
24
-
-
34247636362
-
PPAR γ2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
-
Medina-Gomez G, Gray SL, Yetukuri L et al.: PPAR γ2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. PLoS Genet. 3, E64 (2007).
-
(2007)
PLoS Genet.
, vol.3
-
-
Medina-Gomez, G.1
Gray, S.L.2
Yetukuri, L.3
-
25
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ(PPAR ?)
-
Lehmann JM, Moore LB, Smith-Oliver TA et al.: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator- activated receptor γ(PPAR ?). J. Biol. Chem. 270, 12953-12956 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
-
27
-
-
1542652476
-
Thiazolidinediones, peripheral edema, and Type 2 diabetes: Incidence, pathophysiology, and clinical implications
-
Mudaliar S, Chang AR, Henry RR: Thiazolidinediones, peripheral edema, and Type 2 diabetes: incidence, pathophysiology, and clinical implications. Endocr. Pract. 9, 406-416 (2003).
-
(2003)
Endocr. Pract.
, vol.9
, pp. 406-416
-
-
Mudaliar, S.1
Chang, A.R.2
Henry, R.R.3
-
28
-
-
0036072223
-
Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in Type 2 diabetic patients
-
Miyazaki Y, Mahankali A, Matsuda M et al.: Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in Type 2 diabetic patients. J. Clin. Endocrinol. Metab. 87, 2784-2791 (2002).
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2784-2791
-
-
Miyazaki, Y.1
Mahankali, A.2
Matsuda, M.3
-
29
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Despres JP, Lemieux I: Abdominal obesity and metabolic syndrome. Nature 444, 881-887 (2006).
-
(2006)
Nature
, vol.444
, pp. 881-887
-
-
Despres, J.P.1
Lemieux, I.2
-
30
-
-
34247855853
-
Adipose tissue distribution and risk of metabolic disease: Does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?
-
Yang X, Smith U: Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer? Diabetologia 50, 1127-1139 (2007).
-
(2007)
Diabetologia
, vol.50
, pp. 1127-1139
-
-
Yang, X.1
Smith, U.2
-
31
-
-
0034504237
-
Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
-
Wajchenberg BL: Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr. Rev. 21, 697-738 (2000).
-
(2000)
Endocr. Rev.
, vol.21
, pp. 697-738
-
-
Wajchenberg, B.L.1
-
32
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
Kim JY, van de Wall E, Laplante M et al.: Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117, 2621-2637 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
Van De Wall, E.2
Laplante, M.3
-
33
-
-
34347249246
-
Macrophage infiltration into omental versus subcutaneous fat across different populations: Effect of regional adiposity and the comorbidities of obesity
-
Harman-Boehm I, Bluher M, Redel H et al.: Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity. J. Clin. Endocrinol. Metab. 92, 2240-2247 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 2240-2247
-
-
Harman-Boehm, I.1
Bluher, M.2
Redel, H.3
-
34
-
-
0035502460
-
The biology of white adipocyte proliferation
-
Hausman DB, DiGirolamo M, Bartness TJ, Hausman GJ, Martin RJ: The biology of white adipocyte proliferation. Obes. Rev. 2, 239-254 (2001).
-
(2001)
Obes. Rev.
, vol.2
, pp. 239-254
-
-
Hausman, D.B.1
Digirolamo, M.2
Bartness, T.J.3
Hausman, G.J.4
Martin, R.J.5
-
35
-
-
0032520921
-
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
-
Okuno A, Tamemoto H, Tobe K et al.: Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J. Clin. Invest. 101, 1354-1361 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1354-1361
-
-
Okuno, A.1
Tamemoto, H.2
Tobe, K.3
-
36
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
de Souza CJ, Eckhardt M, Gagen K et al.: Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 50, 1863-1871 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
De Souza, C.J.1
Eckhardt, M.2
Gagen, K.3
-
37
-
-
33750846938
-
Mechanisms of the depot specificity of peroxisome proliferator-activated receptor γ action on adipose tissue metabolism
-
Laplante M, Festuccia WT, Soucy G et al.: Mechanisms of the depot specificity of peroxisome proliferator-activated receptor γ action on adipose tissue metabolism. Diabetes 55, 2771-2778 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 2771-2778
-
-
Laplante, M.1
Festuccia, W.T.2
Soucy, G.3
-
38
-
-
0035798713
-
The mechanisms by which both heterozygous peroxisome proliferator- activated receptor γ (PPARγ) deficiency and PPARγagonist improve insulin resistance
-
Yamauchi T, Kamon J, Waki H et al.: The mechanisms by which both heterozygous peroxisome proliferator-activated receptor ? (PPAR?) deficiency and PPARγagonist improve insulin resistance. J. Biol. Chem. 276, 41245-41254 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41245-41254
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
-
39
-
-
0035933463
-
Stage-specific effects of a thiazolidinedione on proliferation, differentiation and PPARγmRNA expression in 3T3-L1 adipocytes
-
Takamura T, Nohara E, Nagai Y, Kobayashi K: Stage-specific effects of a thiazolidinedione on proliferation, differentiation and PPARγmRNA expression in 3T3-L1 adipocytes. Eur. J. Pharmacol. 422, 23-29 (2001).
-
(2001)
Eur. J. Pharmacol.
, vol.422
, pp. 23-29
-
-
Takamura, T.1
Nohara, E.2
Nagai, Y.3
Kobayashi, K.4
-
40
-
-
0037005631
-
PPARγ-dependent and PPAR?-independent effects on the development of adipose cells from embryonic stem cells
-
Vernochet C, Milstone DS, Iehle C et al.: PPAR?-dependent and PPAR?-independent effects on the development of adipose cells from embryonic stem cells. FEBS Lett. 510, 94-98 (2002).
-
(2002)
FEBS Lett.
, vol.510
, pp. 94-98
-
-
Vernochet, C.1
Milstone, D.S.2
Iehle, C.3
-
41
-
-
0031822518
-
Human preadipocytes display a depot-specific susceptibility to apoptosis
-
Niesler CU, Siddle K, Prins JB: Human preadipocytes display a depot-specific susceptibility to apoptosis. Diabetes 47, 1365-1368 (1998).
-
(1998)
Diabetes
, vol.47
, pp. 1365-1368
-
-
Niesler, C.U.1
Siddle, K.2
Prins, J.B.3
-
42
-
-
17544396164
-
Activators of peroxisome proliferator-activated receptor γhave depot-specific effects on human preadipocyte differentiation
-
Adams M, Montague CT, Prins JB et al.: Activators of peroxisome proliferator-activated receptor γhave depot-specific effects on human preadipocyte differentiation. J. Clin. Invest. 100, 3149-3153 (1997).
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3149-3153
-
-
Adams, M.1
Montague, C.T.2
Prins, J.B.3
-
43
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and Type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM: Mechanisms linking obesity to insulin resistance and Type 2 diabetes. Nature 444, 840-846 (2006).
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
44
-
-
0037312845
-
PPAR-γ activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: Mechanisms for modulation of postprandial lipemia and differential adipose accretion
-
Laplante M, Sell H, MacNaul KL, Richard D, Berger JP, Deshaies Y: PPAR-γ activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: mechanisms for modulation of postprandial lipemia and differential adipose accretion. Diabetes 52, 291-299 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 291-299
-
-
Laplante, M.1
Sell, H.2
MacNaul, K.L.3
Richard, D.4
Berger, J.P.5
Deshaies, Y.6
-
45
-
-
67650564158
-
Depot-specific effects of the PPARγ agonist rosiglitazone on adipose tissue glucose uptake and metabolism
-
Festuccia WT, Blanchard PG, Turcotte V et al.: Depot-specific effects of the PPARγ agonist rosiglitazone on adipose tissue glucose uptake and metabolism. J. Lipid Res. 50, 1185-1194 (2009).
-
(2009)
J. Lipid Res.
, vol.50
, pp. 1185-1194
-
-
Festuccia, W.T.1
Blanchard, P.G.2
Turcotte, V.3
-
46
-
-
33947542353
-
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns
-
Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K: Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J. Biol. Chem. 282, 3450-3457 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 3450-3457
-
-
Donkor, J.1
Sariahmetoglu, M.2
Dewald, J.3
Brindley, D.N.4
Reue, K.5
-
47
-
-
33750872010
-
Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor γactivation
-
Yao-Borengasser A, Rasouli N, Varma V et al.: Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor γactivation. Diabetes 55, 2811-2818 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 2811-2818
-
-
Yao-Borengasser, A.1
Rasouli, N.2
Varma, V.3
-
48
-
-
59649088176
-
Thematic review series: Glycerolipids. Multiple roles for lipins/ phosphatidate phosphatase enzymes in lipid metabolism
-
Reue K, Brindley DN: Thematic review series: glycerolipids. Multiple roles for lipins/ phosphatidate phosphatase enzymes in lipid metabolism. J. Lipid Res. 49, 2493-2503 (2008).
-
(2008)
J. Lipid Res.
, vol.49
, pp. 2493-2503
-
-
Reue, K.1
Brindley, D.N.2
-
49
-
-
0026770646
-
Lactate production in adipose tissue: A regulated function with extra-adipose implications
-
DiGirolamo M, Newby FD, Lovejoy J: Lactate production in adipose tissue: a regulated function with extra-adipose implications. FASEB J. 6, 2405-2412 (1992).
-
(1992)
FASEB J.
, vol.6
, pp. 2405-2412
-
-
Digirolamo, M.1
Newby, F.D.2
Lovejoy, J.3
-
50
-
-
35648967667
-
Adipose tissue integrity as a prerequisite for systemic energy balance: A critical role for peroxisome proliferator-activated receptor γ
-
Anghel SI, Bedu E, Vivier CD et al.: Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor γ. J. Biol. Chem. 282, 29946-29957 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 29946-29957
-
-
Anghel, S.I.1
Bedu, E.2
Vivier, C.D.3
-
51
-
-
0036797450
-
A futile metabolic cycle activated in adipocytes by antidiabetic agents
-
Guan HP, Li Y, Jensen MV, Newgard CB, Steppan CM, Lazar MA: A futile metabolic cycle activated in adipocytes by antidiabetic agents. Nat. Med. 8, 1122-1128 (2002).
-
(2002)
Nat. Med.
, vol.8
, pp. 1122-1128
-
-
Guan, H.P.1
Li, Y.2
Jensen, M.V.3
Newgard, C.B.4
Steppan, C.M.5
Lazar, M.A.6
-
52
-
-
0028988487
-
PPAR γ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz P, Hu E, Devine J, Beale EG, Spiegelman BM: PPAR γ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol. Cell Biol. 15, 351-357 (1995).
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
53
-
-
33748484029
-
PPARγagonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control
-
Festuccia WT, Laplante M, Berthiaume M, Gelinas Y, Deshaies Y: PPARγagonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control. Diabetologia 49, 2427-2436 (2006).
-
(2006)
Diabetologia
, vol.49
, pp. 2427-2436
-
-
Festuccia, W.T.1
Laplante, M.2
Berthiaume, M.3
Gelinas, Y.4
Deshaies, Y.5
-
54
-
-
37149052557
-
PPARγregulates adipose triglyceride lipase in adipocytes in vitro and in vivo
-
Kershaw EE, Schupp M, Guan HP et al.: PPARγregulates adipose triglyceride lipase in adipocytes in vitro and in vivo. Am. J. Physiol. Endocrinol. Metab. 293, E1736-E1745 (2007).
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Kershaw, E.E.1
Schupp, M.2
Guan, H.P.3
-
55
-
-
0035029876
-
Thiazolidinediones increase plasma- adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability
-
Oakes ND, Thalen PG, Jacinto SM, Ljung B: Thiazolidinediones increase plasma- adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability. Diabetes 50, 1158-1165 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1158-1165
-
-
Oakes, N.D.1
Thalen, P.G.2
Jacinto, S.M.3
Ljung, B.4
-
56
-
-
33745784213
-
Thematic review series: Patient-oriented research. Free fatty acid metabolism in human obesity
-
Koutsari C, Jensen MD: Thematic review series: Patient-oriented research. Free fatty acid metabolism in human obesity. J. Lipid Res. 47, 1643-1650 (2006).
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1643-1650
-
-
Koutsari, C.1
Jensen, M.D.2
-
57
-
-
0019216097
-
Reflections on the mechanism of action of hormones
-
Newsholme EA: Reflections on the mechanism of action of hormones. FEBS Lett. 117, K121-K134 (1980).
-
(1980)
FEBS Lett.
, vol.117
-
-
Newsholme, E.A.1
-
58
-
-
0020402824
-
Effects of hormones on the rate of the triacylglycerol/ fatty acid substrate cycle in adipocytes and epididymal fat pads
-
Brooks B, Arch JR, Newsholme EA: Effects of hormones on the rate of the triacylglycerol/ fatty acid substrate cycle in adipocytes and epididymal fat pads. FEBS Lett. 146, 327-330 (1982).
-
(1982)
FEBS Lett.
, vol.146
, pp. 327-330
-
-
Brooks, B.1
Arch, J.R.2
Newsholme, E.A.3
-
59
-
-
0037376373
-
Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo
-
Kalderon B, Mayorek N, Ben-Yaacov L, Bar-Tana J: Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo. Am. J. Physiol. Endocrinol. Metab. 284, E795-E803 (2003).
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.284
-
-
Kalderon, B.1
Mayorek, N.2
Ben-Yaacov, L.3
Bar-Tana, J.4
-
60
-
-
0023900118
-
Hormonal control of substrate cycling in humans
-
Miyoshi H, Shulman GI, Peters EJ, Wolfe MH, Elahi D, Wolfe RR: Hormonal control of substrate cycling in humans. J. Clin. Invest. 81, 1545-1555 (1988).
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1545-1555
-
-
Miyoshi, H.1
Shulman, G.I.2
Peters, E.J.3
Wolfe, M.H.4
Elahi, D.5
Wolfe, R.R.6
-
61
-
-
0025255188
-
Role of triglyceride-fatty acid cycle in controlling fat metabolism in humans during and after exercise
-
Wolfe RR, Klein S, Carraro F, Weber JM: Role of triglyceride-fatty acid cycle in controlling fat metabolism in humans during and after exercise. Am. J. Physiol. 258, E382-E389 (1990).
-
(1990)
Am. J. Physiol.
, vol.258
-
-
Wolfe, R.R.1
Klein, S.2
Carraro, F.3
Weber, J.M.4
-
62
-
-
39049125626
-
Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased
-
Frayn KN, Langin D, Karpe F: Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased. Diabetologia 51, 394-397 (2008).
-
(2008)
Diabetologia
, vol.51
, pp. 394-397
-
-
Frayn, K.N.1
Langin, D.2
Karpe, F.3
-
63
-
-
0017106971
-
Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue
-
Harper RD, Saggerson ED: Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue. J. Lipid Res. 17, 516-526 (1976).
-
(1976)
J. Lipid Res.
, vol.17
, pp. 516-526
-
-
Harper, R.D.1
Saggerson, E.D.2
-
64
-
-
85047689659
-
Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
-
Wilson-Fritch L, Nicoloro S, Chouinard M et al.: Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. J. Clin. Invest. 114, 1281-1289 (2004).
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1281-1289
-
-
Wilson-Fritch, L.1
Nicoloro, S.2
Chouinard, M.3
-
65
-
-
14644415905
-
Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients
-
Boden G, Homko C, Mozzoli M, Showe LC, Nichols C, Cheung P: Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients. Diabetes 54, 880-885 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 880-885
-
-
Boden, G.1
Homko, C.2
Mozzoli, M.3
Showe, L.C.4
Nichols, C.5
Cheung, P.6
-
66
-
-
17844385363
-
Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo
-
Bogacka I, Xie H, Bray GA, Smith SR: Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes 54, 1392-1399 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 1392-1399
-
-
Bogacka, I.1
Xie, H.2
Bray, G.A.3
Smith, S.R.4
-
67
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon B, Nedergaard J: Brown adipose tissue: function and physiological significance. Physiol. Rev. 84, 277-359 (2004).
-
(2004)
Physiol. Rev.
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
68
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G et al.: Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360, 1509-1517 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
-
70
-
-
52649150323
-
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγagonist
-
Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J: Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγagonist. Am. J. Physiol. Endocrinol. Metab. 295, E287-E296 (2008).
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
-
-
Petrovic, N.1
Shabalina, I.G.2
Timmons, J.A.3
Cannon, B.4
Nedergaard, J.5
-
71
-
-
66149110724
-
The PPARγagonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake
-
Festuccia WT, Blanchard PG, Turcotte V et al.: The PPARγagonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296, R1327-R1335 (2009).
-
(2009)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.296
-
-
Festuccia, W.T.1
Blanchard, P.G.2
Turcotte, V.3
-
73
-
-
3843083938
-
Peroxisome proliferator-activated receptor γ agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice
-
Sell H, Berger JP, Samson P et al.: Peroxisome proliferator-activated receptor γ agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice. Endocrinology 145, 3925-3934 (2004).
-
(2004)
Endocrinology
, vol.145
, pp. 3925-3934
-
-
Sell, H.1
Berger, J.P.2
Samson, P.3
-
74
-
-
42449109965
-
Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status
-
Festuccia WT, Oztezcan S, Laplante M et al.: Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status. Endocrinology 149, 2121-2130 (2008).
-
(2008)
Endocrinology
, vol.149
, pp. 2121-2130
-
-
Festuccia, W.T.1
Oztezcan, S.2
Laplante, M.3
-
75
-
-
0031575934
-
Differential expression of PPAR γ1 and γ2 isoforms in human adipose tissue
-
Yanase T, Yashiro T, Takitani K et al.: Differential expression of PPAR γ1 and γ2 isoforms in human adipose tissue. Biochem. Biophys. Res. Commun. 233, 320-324 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 320-324
-
-
Yanase, T.1
Yashiro, T.2
Takitani, K.3
-
76
-
-
0031964987
-
Depot-specific differences in adipose tissue gene expression in lean and obese subjects
-
Lefebvre AM, Laville M, Vega N et al.: Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes 47, 98-103 (1998).
-
(1998)
Diabetes
, vol.47
, pp. 98-103
-
-
Lefebvre, A.M.1
Laville, M.2
Vega, N.3
-
77
-
-
0031678588
-
Depot-related gene expression in human subcutaneous and omental adipocytes
-
Montague CT, Prins JB, Sanders L et al.: Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes 47, 1384-1391 (1998).
-
(1998)
Diabetes
, vol.47
, pp. 1384-1391
-
-
Montague, C.T.1
Prins, J.B.2
Sanders, L.3
-
78
-
-
0037184960
-
SRC-1 and TIF2 control energy balance between white and brown adipose tissues
-
Picard F, Gehin M, Annicotte J et al.: SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell 111, 931-941 (2002).
-
(2002)
Cell
, vol.111
, pp. 931-941
-
-
Picard, F.1
Gehin, M.2
Annicotte, J.3
-
79
-
-
2942532305
-
Nuclear receptor corepressor RIP140 regulates fat accumulation
-
Leonardsson G, Steel JH, Christian M et al.: Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc. Natl Acad. Sci. USA 101, 8437-8442 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 8437-8442
-
-
Leonardsson, G.1
Steel, J.H.2
Christian, M.3
-
80
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K: Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
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