-
1
-
-
0035908493
-
Blocking oncogenic ras signaling for cancer therapy
-
ADJEI, A.A. (2001). Blocking oncogenic ras signaling for cancer therapy. J. Natl. Cancer Inst. 93, 1062-1074.
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
2
-
-
0028850751
-
Pharmacokinetics of antisense oligonucleotides
-
AGRAWAL, S., TEMSAMAMI, J., GALBARAITH, W., and TANG, J. (1995). Pharmacokinetics of antisense oligonucleotides. Clin. Pharmacokinet. 28, 7-16.
-
(1995)
Clin. Pharmacokinet
, vol.28
, pp. 7-16
-
-
Agrawal, S.1
Temsamami, J.2
Galbaraith, W.3
Tang, J.4
-
3
-
-
0025743216
-
Pharmacokinetics, biodistribution, and stability of oligonucle-otides phosphorothioates in mice
-
AGRAWAL, S., TEMSAMAMI, J., and TANG, J.Y. (1991). Pharmacokinetics, biodistribution, and stability of oligonucle-otides phosphorothioates in mice. Proc. Natl. Acad. Sci. USA. 88, 7597-7599.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7597-7599
-
-
Agrawal, S.1
Temsamami, J.2
Tang, J.Y.3
-
4
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
ALMOGUERA, C., SHIBATA, D., FORRESTER, K., MARTIN, J., ARNHEIM, N., and PERUCHO, M. (1988). Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell. 53, 549-554.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
5
-
-
0029821897
-
Inhibition of human cytomegalo-virus immediate-early gene expression by an antisense oligo-nucleotides complementary to immediate-early RNA
-
ANDERSON, K.P., FOX, M.C., BROWN-DRIVER, V., MARTIN, M.J., and AZAD, R.F. (1996). Inhibition of human cytomegalo-virus immediate-early gene expression by an antisense oligo-nucleotides complementary to immediate-early RNA. Agents. Chemother. 40, 2004-2011.
-
(1996)
Agents. Chemother
, vol.40
, pp. 2004-2011
-
-
Anderson, K.P.1
Fox, M.C.2
Brown-Driver, V.3
Martin, M.J.4
Azad, R.F.5
-
6
-
-
0027216834
-
Antiviral activity of a phosphorothio-ate oligonucleotides complementary to RNA of the Human cyto-megalovirus major immediate-early region
-
AZAD, R.F., DRIVER, V.B., TANAKA, K., CROOKE, R.M., and ANDERSON, K.P. (1993). Antiviral activity of a phosphorothio-ate oligonucleotides complementary to RNA of the Human cyto-megalovirus major immediate-early region. Antimicrob. Agents. Chemother. 37, 1945-1954.
-
(1993)
Antimicrob. Agents. Chemother
, vol.37
, pp. 1945-1954
-
-
Azad, R.F.1
Driver, V.B.2
Tanaka, K.3
Crooke, R.M.4
Anderson, K.P.5
-
8
-
-
31144454066
-
Key cancer cell signal transduction pathways as therapeutic targets
-
BIANCO, R., MELISI, D., CIARDIELLO, F., and TORTORA, G. (2006). Key cancer cell signal transduction pathways as therapeutic targets. Eur. J. Cancer 42, 290-294.
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 290-294
-
-
Bianco, R.1
Melisi, D.2
Ciardiello, F.3
Tortora, G.4
-
9
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
BOS, J.L. (1989). ras oncogenes in human cancer: a review. Cancer Res. 49, 4682-4689.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
10
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
BRUMMELKAMP, T.R., BERNARDS, R., and AGAMI, R. (2002). Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2, 243-247.
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
11
-
-
0025942816
-
Frequency and spectrum of mutations at codon 12 and 13 of the C-K-ras gene in human tumors
-
CAPELLA, G., CRONAUER-MITRA, S., PEINADO, M.A., and PERUCHO, M. (1991). Frequency and spectrum of mutations at codon 12 and 13 of the c-K-ras gene in human tumors. Environ. Health. Persp. 93, 125-131.
-
(1991)
Environ. Health. Persp
, vol.93
, pp. 125-131
-
-
Capella, G.1
Cronauer-Mitra, S.2
Peinado, M.A.3
Perucho, M.4
-
12
-
-
0021891866
-
Psoralens as photoactive probes of nucleic acid structure and function: Organic chemistry, photochemistry, and biochemistry
-
CIMINO, G.D., GAMPER, H.B., ISAACS, S., and HEARST, J. (1985). Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry. Ann. Rev. Biochem. 54, 1151-1193.
-
(1985)
Ann. Rev. Biochem
, vol.54
, pp. 1151-1193
-
-
Cimino, G.D.1
Gamper, H.B.2
Isaacs, S.3
Hearst, J.4
-
13
-
-
0023447259
-
Selective elimination of mRNAs in vivo: Complementary oligonucleotides promote RNA degradation by an RNase H-like activity
-
DASH, P., LOTAN, I., KNAPP, I., KANDEL, E.R., and GOELET, P. (1987). Selective elimination of mRNAs in vivo: complementary oligonucleotides promote RNA degradation by an RNase H-like activity. Proc. Natl. Acad. Sci. USA. 84, 7896-7900.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7896-7900
-
-
Dash, P.1
Lotan, I.2
Knapp, I.3
Kandel, E.R.4
Goelet, P.5
-
14
-
-
1642430704
-
Antisense oligonucle-otides-based therapeutics for cancer
-
DEAN, N.M., and BANNETT, C.F. (2003). Antisense oligonucle-otides-based therapeutics for cancer. Oncogene. 22, 9087-9096.
-
(2003)
Oncogene
, vol.22
, pp. 9087-9096
-
-
Dean, N.M.1
Bannett, C.F.2
-
16
-
-
20344371233
-
Antisense therapy for cancer
-
GLEAVE, M.E., and MONIA, B.P. (2005). Antisense therapy for cancer. Nat. Rev. Cancer. 5, 468-479.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 468-479
-
-
Gleave, M.E.1
Monia, B.P.2
-
17
-
-
0023046569
-
Translation arrest by oligonucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length
-
HAEUPTLE, M.T., FRANK, R., and DOBBERSTEIN, B. (1986). Translation arrest by oligonucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length. Nucleic Acids Res. 14, 14 2 7-14 4 8.
-
(1986)
Nucleic Acids Res
, vol.14
, pp. 1427-1448
-
-
Haeuptle, M.T.1
Frank, R.2
Dobberstein, B.3
-
18
-
-
36048948861
-
Properties of novel antisense oligonucleotides containing 2′-O-modif ed adenosine with a photo-reactive group
-
HIGUCHI, M., SAKAMOTO, T., KOBORI, A., and MURAKAMI, A. (2006). Properties of novel antisense oligonucleotides containing 2′-O-modif ed adenosine with a photo-reactive group. Nucleic Acids Symp. Ser. 50, 301-302.
-
(2006)
Nucleic Acids Symp. ser
, vol.50
, pp. 301-302
-
-
Higuchi, M.1
Sakamoto, T.2
Kobori, A.3
Murakami, A.4
-
19
-
-
42949160156
-
Selective regulation of mutant K-ras mRNA expression by photo-cross-linking antisense oligonucleotides
-
HIGUCHI, M., YAMAYOSHI, A., KOBORI, A., and MURAKAMI, A. (2007a). Selective regulation of mutant K-ras mRNA expression by photo-cross-linking antisense oligonucleotides. Nucleic Acids Symp. Ser. 51, 443-444.
-
(2007)
Nucleic Acids Symp. ser
, vol.51
, pp. 443-444
-
-
Higuchi, M.1
Yamayoshi, A.2
Kobori, A.3
Murakami, A.4
-
20
-
-
34147130198
-
Selective photo-cross-linking of 2′-O-psoralen-conjugated oligonucleotides with RNAs having point mutations
-
HIGUCHI, M., YAMAYOSHI, A., YAMAGUCHI, T., IWASE, R., YAMAOKA, T., and MURAKAMI, A. (2007b). Selective photo-cross-linking of 2′-O-psoralen- conjugated oligonucleotides with RNAs having point mutations. Nucleosides Nucleotides Nucleic Acids 26, 277-290.
-
(2007)
Nucleosides Nucleotides Nucleic Acids
, vol.26
, pp. 277-290
-
-
Higuchi, M.1
Yamayoshi, A.2
Yamaguchi, T.3
Iwase, R.4
Yamaoka, T.5
Murakami, A.6
-
21
-
-
0025894713
-
P53 mutations in human cancers
-
HOLLSTEIN, M., SIDRANSKY, D., VOGELSTEIN, B., and HARRIS, C.C. (1991). p53 mutations in human cancers. Science 253, 49-53.
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
22
-
-
0037685280
-
Expression prof ling reveals off target gene regulation by RNAi
-
JACKSON, A.L., BARTZ, S.R., SCHELTER, J., KOBAYASHI, S.V., BURCHARD, J., MAO, M., LI, B., CAVET, G., and LINSLEY, P.S. (2003). Expression prof ling reveals off target gene regulation by RNAi. Nat. Biol. 21, 635-637.
-
(2003)
Nat. Biol
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
24
-
-
0024239838
-
Photochemical cross-linking of psoralen-derivatized oligonucleoside methylphosphonates to Rabbit glo-bin messenger RNA
-
KEAN, J.M., MURAKAMI, A., BLAKE, K.R., CUSHMAN, C.D., and MILLER, P.S. (1988). Photochemical cross-linking of psoralen-derivatized oligonucleoside methylphosphonates to Rabbit glo-bin messenger RNA. Biochemistry 27, 9113-9121.
-
(1988)
Biochemistry
, vol.27
, pp. 9113-9121
-
-
Kean, J.M.1
Murakami, A.2
Blake, K.R.3
Cushman, C.D.4
Miller, P.S.5
-
25
-
-
0037733977
-
Antisense technologies
-
KURRECK, J. (2003). Antisense technologies. Eur. J. Biochem. 270, 1628-164 4.
-
(2003)
Eur. J. Biochem
, vol.270
, pp. 1628-1644
-
-
Kurreck, J.1
-
26
-
-
0024276831
-
Interaction of psoralen-derivatized oligonucleoside methylphosphonates with single-stranded DNA
-
LEE, B.L., MURAKAMI, A., BLAKE, K.R., LIN, S.B., and MILLER, P.S. (1988). Interaction of psoralen-derivatized oligonucleoside methylphosphonates with single-stranded DNA. Biochemistry 27, 3197-3203.
-
(1988)
Biochemistry
, vol.27
, pp. 3197-3203
-
-
Lee, B.L.1
Murakami, A.2
Blake, K.R.3
Lin, S.B.4
Miller, P.S.5
-
27
-
-
0035989886
-
Oligonucleotide conjugates as potential antisense drugs with improved uptake, biodistribution, targeted delivery, and mechanism of action
-
MANOHARAN, M. (2002). Oligonucleotide conjugates as potential antisense drugs with improved uptake, biodistribution, targeted delivery, and mechanism of action. Antisense Nucleic Acid Drug Dev. 12, 103-128.
-
(2002)
Antisense Nucleic Acid Drug Dev
, vol.12
, pp. 103-128
-
-
Manoharan, M.1
-
28
-
-
0035060451
-
Photodynamic antisense regulation of human cervical carcinoma cell growth using psoralen-conjugated oligo(nucleoside phosphorothioate)
-
MURAKAMI, A., YAMAYOSHI, A., IWASE, R., NISHIDA, J., YAMAOKA, T., and WAKE, N. (2001). Photodynamic antisense regulation of human cervical carcinoma cell growth using psoralen-conjugated oligo(nucleoside phosphorothioate). Eur. J. Pharma. Sci. 13, 25-34.
-
(2001)
Eur. J. Pharma. Sci
, vol.13
, pp. 25-34
-
-
Murakami, A.1
Yamayoshi, A.2
Iwase, R.3
Nishida, J.4
Yamaoka, T.5
Wake, N.6
-
29
-
-
16544390524
-
K-ras and H-ras activation promote distinct consequences on endometrial cell survival
-
NINOMIYA, Y., KATO, K., TAKAHASHI, A., UEOKA, Y., KIMIKIHARA, T., ARIMA, T., MATSUDA, T., KATO, H., NISHIDA, J., and WAKE, N. (2004). K-ras and H-ras activation promote distinct consequences on endometrial cell survival. Cancer Res. 64, 2759-2765.
-
(2004)
Cancer Res
, vol.64
, pp. 2759-2765
-
-
Ninomiya, Y.1
Kato, K.2
Takahashi, A.3
Ueoka, Y.4
Kimikihara, T.5
Arima, T.6
Matsuda, T.7
Kato, H.8
Nishida, J.9
Wake, N.10
-
30
-
-
0035949494
-
Spatially localized generation of nucleotide sequence-specif c DNA damage
-
OH, D.H., KING, B.A., BOXER, S.G., and HANAWALT, P.C. (2001). Spatially localized generation of nucleotide sequence-specif c DNA damage. Proc. Natl. Acad. Sci. USA. 98, 11271-11276.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11271-11276
-
-
Oh, D.H.1
King, B.A.2
Boxer, S.G.3
Hanawalt, P.C.4
-
31
-
-
0031056216
-
Two-photon excitation of 4′-hydroxymethyl-4,5′-8- trimethylpsoralen
-
OH, D.H., STANLEY, R.J., LIN, M., HOEFFLER, W.K., BOXER, S.G., BERNS, M.W., and BAUER, E.A. (1997). Two-photon excitation of 4′-hydroxymethyl-4, 5′-8-trimethylpsoralen. Photochem. Photobiol. 65, 91-95.
-
(1997)
Photochem. Photobiol
, vol.65
, pp. 91-95
-
-
Oh, D.H.1
Stanley, R.J.2
Lin, M.3
Hoeffler, W.K.4
Boxer, S.G.5
Berns, M.W.6
Bauer, E.A.7
-
32
-
-
0025736802
-
Short modif ed antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation
-
SAISON-BEHMOARAS, T., TOCQUE, B., REY, I., CHASSIGNOL, M., THOUONG, N.T., and HELENE, C. (1991). Short modif ed antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation. EMBO J. 10, 1111-1118.
-
(1991)
EMBO J
, vol.10
, pp. 1111-1118
-
-
Saison-Behmoaras, T.1
Tocque, B.2
Rey, I.3
Chassignol, M.4
Thouong, N.T.5
Helene, C.6
-
33
-
-
10744219688
-
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
-
SCACHERI, P.C., ROZENBLATT-ROSEN, O., CAPLEN, N.J., WOLFSBERG, T.G., UMAYAM, L., LEE, J.C., HUGHES, C.M., SHANMUGAM, K.S., BHATTACHARJEE, A., MEYERSON, M., and COLLINS, F.S. (2004). Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc. Natl. Acad. Sci. USA. 101, 1892-1897.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1892-1897
-
-
Scacheri, P.C.1
Rozenblatt-Rosen, O.2
Caplen, N.J.3
Wolfsberg, T.G.4
Umayam, L.5
Lee, J.C.6
Hughes, C.M.7
Shanmugam, K.S.8
Bhattacharjee, A.9
Meyerson, M.10
Collins, F.S.11
-
34
-
-
0023735997
-
KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas
-
SMIT, V.T.H.B.M., BOOT, A.J.M., SMITS, A.M.M., FLEUREN, G.J., CORNELISSE, C.J., and BOS, J.L. (1988). KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas. Nucleic Acids Res. 16, 7773-7782.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 7773-7782
-
-
Smit, V.T.H.B.M.1
Boot, A.J.M.2
Smits, A.M.M.3
Fleuren, G.J.4
Cornelisse, C.J.5
Bos, J.L.6
-
35
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents is the bullet really magical?
-
STEIN, C.A., and CHENG, Y.C. (1993). Antisense oligonucleotides as therapeutic agents is the bullet really magical?. Science 261, 1004-1012.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.C.2
-
36
-
-
33745625836
-
Therapeutic potential of RNA interference against cancer
-
TAKESHITA, F., and OCHIYA, T. (2006). Therapeutic potential of RNA interference against cancer. Cancer Sci. 97, 689-696.
-
(2006)
Cancer Sci
, vol.97
, pp. 689-696
-
-
Takeshita, F.1
Ochiya, T.2
-
37
-
-
0035947018
-
Regulation of cell cycle molecules by the ras effecter system
-
TAKUWA, N., and TAKUWA, Y. (2001). Regulation of cell cycle molecules by the ras effecter system. Mol. Cell. Endocrinol. 177, 25-33.
-
(2001)
Mol. Cell. Endocrinol
, vol.177
, pp. 25-33
-
-
Takuwa, N.1
Takuwa, Y.2
-
38
-
-
0023619575
-
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect onco-genic mutants
-
TRAHEY, M., and MCCORMICK, F. (1987). A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect onco-genic mutants. Science 238, 542-545.
-
(1987)
Science
, vol.238
, pp. 542-545
-
-
Trahey, M.1
McCormick, F.2
-
39
-
-
0021760744
-
Activation of a human c-K-ras oncogene
-
YAMAMOTO, F., and PERUCHO, M. (1984). Activation of a human c-K-ras oncogene. Nucleic Acids Res. 12, 8873-8885.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 8873-8885
-
-
Yamamoto, F.1
Perucho, M.2
-
40
-
-
34247512483
-
Specif c apoptosis induction in human papillomavirus-positive cervical carcinoma cells by photodynamic antisense regulation
-
YAMAYOSHI, A., KATO, K., SUGA, S., ICHINOE, A., ARIMA, T., MATSUDA, T., KATO, H., MURAKAMI, A., and WAKE, N. (2007). Specif c apoptosis induction in human papillomavirus-positive cervical carcinoma cells by photodynamic antisense regulation. Oligonucleotide 17, 66-79.
-
(2007)
Oligonucleotide
, vol.17
, pp. 66-79
-
-
Yamayoshi, A.1
Kato, K.2
Suga, S.3
Ichinoe, A.4
Arima, T.5
Matsuda, T.6
Kato, H.7
Murakami, A.8
Wake, N.9
-
41
-
-
33846973375
-
Knockdown of mutant K-ras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells
-
ZHANG, Z., JIANG, G., YANG, F., and WANG, J. (2006). Knockdown of mutant K-ras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells. Cancer Biol. Ther. 5, 14 81-14 8 6. (Pubitemid 46256617)
-
(2006)
Cancer Biology and Therapy
, vol.5
, Issue.11
, pp. 1481-1486
-
-
Zhang, Z.1
Jiang, G.2
Yang, F.3
Wang, J.4
|