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Volumn 878, Issue 9-10, 2010, Pages 749-757
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Development and validation of a method for the determination of a therapeutic peptide with affinity for the human B1 receptor in human plasma using HPLC-MS/MS
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Author keywords
96 well SPE; Absorption; HPLC MS MS; Peptide; SPE
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Indexed keywords
96-WELL;
96-WELL PLATE;
96-WELL SPE;
APPLIED BIOSYSTEMS;
CHRONIC PAIN;
CLINICAL TRIAL;
COEFFICIENTS OF VARIATIONS;
CONCENTRATION RANGES;
CV VALUE;
HPLC-MS/MS;
HUMAN PLASMAS;
INTERNAL STANDARDS;
ISOTOPICALLY LABELED;
PLASMA SAMPLES;
SYNTHETIC PEPTIDE;
THERAPEUTIC PEPTIDES;
ABSORPTION;
AMINO ACIDS;
BIOLOGICAL SYSTEMS;
CUSTOMER SATISFACTION;
ELECTROSPRAY IONIZATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
ORGANIC ACIDS;
PLASMA (HUMAN);
PLASMAS;
QUALITY CONTROL;
SOLAR RADIATION;
TOTAL QUALITY MANAGEMENT;
PEPTIDES;
B1 PEPTIDE;
BRADYKININ B1 RECEPTOR;
BRADYKININ B1 RECEPTOR ANTAGONIST;
UNCLASSIFIED DRUG;
ARTICLE;
BLOOD SAMPLING;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG STABILITY;
DRUG STRUCTURE;
ELECTROSPRAY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN EXPERIMENT;
MASS SPECTROMETRY;
NORMAL HUMAN;
PRIORITY JOURNAL;
QUALITY CONTROL;
RECEPTOR AFFINITY;
SOLID PHASE EXTRACTION;
VALIDATION PROCESS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
HUMANS;
NEOPLASM PROTEINS;
PAIN;
PEPTIDES;
PROTEIN BINDING;
TANDEM MASS SPECTROMETRY;
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EID: 77549088269
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.01.018 Document Type: Article |
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Times cited : (16)
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References (16)
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