Quantitative analysis of a model opioid peptide and its cyclic prodrugs in rat plasma using high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 780, Issue 2, 2002, Pages 269-281

  Yang, Jerry Z ^a   Bastian, K C ^a,b   Moore, Randy D ^a,c   Stobaugh, John F ^a   Borchardt, Ronald T ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b AAI   (United States)

^c NONE   (United States)

Author keywords

Cyclic prodrugs; DADLE; Derivatization, LC; Opioid peptides

Indexed keywords

ENKEPHALIN[2 ALANINE 5 LEUCINE]; PRODRUG; ACETONITRILE; AMINO TYROSINE DEXTRO ALANYLGLYCYLPHENYLALANINE DEXTRO LEUCINE CARBOXYLIC ACID; CYANIDE; FORMIC ACID; ISOINDOLE DERIVATIVE; OPIATE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ANIMAL; ARTICLE; BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; RAT; REPRODUCIBILITY; SPECTROFLUOROMETRY; ACCURACY; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; BLOOD ANALYSIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DERIVATIZATION; DRUG METABOLISM; DRUG STABILITY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENKEPHALIN, LEUCINE-2-ALANINE; MASS SPECTROMETRY; PRODRUGS; RATS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE;

ACETONITRILE; ALDEHYDES; BIOCONVERSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NAPHTHALENE; PRECIPITATION (CHEMICAL); PROTEINS;

SOLID-PHASE EXTRACTION (SPE);

DRUG PRODUCTS;

EID: 0037175451     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00536-6     Document Type: Article

References (33)

1. Gangwar S., Pauletti G.M., Wang B., Siahaan T.J., Stella V.J., Borchardt R.T. Drug Discov. Today. 2:1997;148.
2. Gangwar S., Pauletti G.M., Siahaan T.J., Stella V.J., Borchardt R.T. J. Org. Chem. 62:1997;1356.
3. Pauletti G.M., Gangwar S., Okumu F.W., Siahaan T.J., Stella V.J., Borchardt R.T. Pharm. Res. 13:1996;1615.
4. Wang B., Gangwar S., Pauletti G.M., Siahaan T.J., Borchardt R.T. J. Org. Chem. 62:1997;1363.
5. Pauletti G.M., Gangwar S., Wang B., Borchardt R.T. Pharm. Res. 14:1997;11.
6. Gudmundsson O.S., Pauletti G.M., Wang W., Shan D., Zhang H., Wang B., Borchardt R.T. Pharm. Res. 16:1999;7.
7. Bak A., Gudmundsson O.S., Friis G.J., Siahaan T.J., Borchardt R.T. Pharm. Res. 16:1999;24.
8. Gudmundsson O.S., Nimkar K., Gangwar S., Siahaan T., Borchardt R.T. Pharm. Res. 16:1999;16.
9. Nyberg F., Pernow C., Moberg U., Eriksson R.B. J. Chromatogr. 359:1986;541.
10. Pacakova V., Suchankova J., Stulik K. J. Chromatogr. B. 681:1996;69.
11. Ranta V.P., Hamalainen K.M., Auriola S., Urtti A. J. Chromatogr. B. 709:1998;1.
12. Shibanoki S., Weinberger S.B., Ishikawa K., Martinez J.L. J. Chromatogr. 532:1990;249.
13. Monger L.S., Olliff C.J. J. Chromatogr. 577:1992;239.
14. de Montigny P., Stobaugh J.F., Givens R.S., Carlson R.G., Srinivasachar K., Sternson L.A., Higuchi T. Anal. Chem. 59:1987;1096.
15. Mifune M., Krehbiel D.K., Stobaugh J.F., Riley C.M. J. Chromatogr. 496:1989;55.
16. de Montigny P., Riley C.M., Sternson L.A., Stobaugh J.F. J. Pharm. Biomed. Anal. 8:1990;419.
17. Kai M., Nakashima A., Ohkura Y. J. Chromatogr. B. 688:1997;205.
18. Kanazawa H., Nagatsuka T., Miyazaki M., Matsushima Y. J. Chromatogr. A. 763:1997;23.
19. Shangguan D., Zhao Y., Han H., Zhao R., Liu G. Anal. Chem. 73:2001;2054.
20. Tseng J.L., Yan L., Fridland G.H., Desiderio D.M. Rapid Commun. Mass Spectrom. 9:1995;264.
21. Marquez C.D., Weintraub S.T., Smith P.C. J. Chromatogr. B. 694:1997;21.
22. Zagrobelny J., Chavez C., Constanzer M.L., Matuszewski B.K. J. Pharm. Biomed. Anal. 15:1997;1427.
23. Chavez-Eng C.M., Schwartz M., Constanzer M.L., Matuszewski B.K. J. Chromatogr. B. 721:1999;229.
24. Peng J., Gygi S.P. J. Mass Spectrom. 36:2001;1083.
25. Zhang H., Henion J. J. Chromatogr. B. 757:2001;151.
26. Majumdar T.K., Wu S., Tse F.L. J. Chromatogr. B. 759:2001;99.
27. Hsieh Y., Bryant M.S., Brisson J.M., Ng K., Korfmacher W.A. J. Chromatogr. B. 767:2002;353.
28. Wang B., Nimkar K., Wang W., Zhang H., Shan D., Gudmundsson O., Gangwar S., Siahaan T., Borchardt R.T. J. Pept. Res. 53:1999;370.
29. Bak A., Siahaan T.J., Gudmundsson O.S., Gangwar S., Friis G.J., Borchardt R.T. J. Pept. Res. 53:1999;393.
30. Eichhorn P., Knepper T.P. J. Mass Spectrom. 36:2001;677.
31. Yamaguchi J., Matsuno Y., Hachiuma K., Ogawa N., Higuchi S. Rapid Commun. Mass Spectrom. 15:2001;629.
32. Volmer D.A., Lock C.M. Rapid Commun. Mass Spectrom. 12:1998;157.
33. Matuszewski B.K., Constanzer M.L., Chavez-Eng C.M. Anal. Chem. 70:1998;882.