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18
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29044439970
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Isomerization of terminal alkene occurred to some extent during RCM without p-benzoquinone. See also for the effect of p-benzoquinone:
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Isomerization of terminal alkene occurred to some extent during RCM without p-benzoquinone. See also for the effect of p-benzoquinone:. Hong S.H., Sanders D.P., Lee C.W., and Grubbs R.H. J. Am. Chem. Soc. 127 (2005) 17160-17161
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77549085894
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For diversifolin numbering, see 1a,b,d
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For diversifolin numbering, see 1a,b,d.
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21
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0001649946
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note
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Direct RCM reaction of diol 12 was not successful due to the decomposition of the starting material.
-
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25
-
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77549085549
-
-
note
-
3b
-
-
-
-
26
-
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77549086014
-
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note
-
In the previous synthesis, the corresponding diol was directly treated with NaH, followed by the acylation with isobutyryl chloride. In the present synthesis, however, it is necessary to discriminate the two hydroxyl groups at C5 and C8.
-
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31
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