An efficient one-pot synthesis of C2-symmetric triazolophanes by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction

Tetrahedron Letters

Volumn 51, Issue 14, 2010, Pages 1896-1898

  Rajesh, R ^a   Periyasami, G ^a   Raghunathan, R ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

1,3 Dipolar cycloaddition; Click chemistry; CuAAC; Triazole; Triazolophanes

Indexed keywords

ALKYNE; AZIDE; COPPER; MACROCYCLIC COMPOUND; TRIAZOLE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CYCLOADDITION; METHODOLOGY; ONE POT SYNTHESIS; SOLVENT EFFECT;

EID: 77549084174     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.02.020     Document Type: Article

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26. 4 and concentrated. The residue was purified by silica gel flash column chromatography using chloroform/methanol (9:1) to give the pure product 4a.
27. 6O: C, 70.23; H, 5.40; N, 20.47. Found: C, 70.12; H, 5.51; N, 20.58.