Cigarette smoke-induced pulmonary endothelial dysfunction is partially suppressed by sildenafil

European Journal of Pharmaceutical Sciences

Volumn 39, Issue 5, 2010, Pages 363-372

  Milara, Javier ^a   Juan, Gustavo ^a   Ortiz, Jose L ^b   Guijarro, Ricardo ^a   Losada, Mercedes ^b   Serrano, Adela ^a   Morcillo, Esteban J ^b,c,d   Cortijo, Julio ^b,c  

^a HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

Endothelial dysfunction; Human pulmonary artery endothelial cells; Oxidative stress; Sildenafil

Indexed keywords

ACETYLCYSTEINE; ANGIOTENSIN I; ANGIOTENSIN II; CIGARETTE SMOKE; CYCLIC GMP; DIPHENYLIODONIUM SALT; INTERLEUKIN 6; INTERLEUKIN 8; NITRIC OXIDE; PHOSPHODIESTERASE V; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SILDENAFIL;

APOPTOSIS; ARTICLE; CELL LEVEL; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY;

BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LUNG; NITRIC OXIDE; PIPERAZINES; POLYMERASE CHAIN REACTION; PURINES; SMOKE; SULFONES; TOBACCO; VASODILATOR AGENTS;

EID: 77549083365     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.01.005     Document Type: Article

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