-
1
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
S. R. Sprang, G protein mechanisms: Insights from structural analysis. Annu. Rev. Biochem. 66, 639-678 (1997).
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
3
-
-
0035834388
-
The guanine nucleotide-binding switch in three dimensions
-
I. R. Vetter, A. Wittinghofer, The guanine nucleotide-binding switch in three dimensions. Science 294, 1299-1304 (2001).
-
(2001)
Science
, vol.294
, pp. 1299-1304
-
-
Vetter, I.R.1
Wittinghofer, A.2
-
4
-
-
34249018367
-
GEFs and GAPs: Critical elements in the control of small G proteins
-
J. L. Bos, H. Rehmann, A. Wittinghofer, GEFs and GAPs: Critical elements in the control of small G proteins. Cell 129, 865-877 (2007).
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
5
-
-
0034213327
-
Rho GTPases and their effector proteins
-
A. L. Bishop, A. Hall, Rho GTPases and their effector proteins. Biochem. J. 348, 241-255 (2000).
-
(2000)
Biochem. J.
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
6
-
-
2342418629
-
Rho-family GTPases: It's not only Rac and Rho (and I like it)
-
K. Wennerberg, C. J. Der, Rho-family GTPases: It's not only Rac and Rho (and I like it). J. Cell Sci. 117, 1301-1312 (2004).
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1301-1312
-
-
Wennerberg, K.1
Der, C.J.2
-
7
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
K. L. Rossman, C. J. Der, J. Sondek, GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
8
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
E. Brugnera, L. Haney, C. Grimsley, M. Lu, S. F. Walk, A. C. Tosello-Trampont, I. G. Macara, H. Madhani, G. R. Fink, K. S. Ravichandran, Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat. Cell Biol. 4, 574-582 (2002).
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
Macara, I.G.7
Madhani, H.8
Fink, G.R.9
Ravichandran, K.S.10
-
9
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
J. F. Cote, K. Vuori, Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115, 4901-4913 (2002).
-
(2002)
J. Cell Sci.
, vol.115
, pp. 4901-4913
-
-
Cote, J.F.1
Vuori, K.2
-
10
-
-
0036713381
-
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins
-
N. Meller, M. Irani-Tehrani, W. B. Kiosses, M. A. Del Pozo, M. A. Schwartz, Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nat. Cell Biol. 4, 639-647 (2002).
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 639-647
-
-
Meller, N.1
Irani-Tehrani, M.2
Kiosses, W.B.3
Del Pozo, M.A.4
Schwartz, M.A.5
-
11
-
-
34548472221
-
GEF what? Dock180 and related proteins help Rac to polarize cells in new ways
-
J. F. Cote, K. Vuori, GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. Trends Cell Biol. 17, 383-393 (2007).
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 383-393
-
-
Cote, J.F.1
Vuori, K.2
-
12
-
-
27944445790
-
CZH proteins: A new family of Rho-GEFs
-
N. Meller, S. Merlot, C. Guda, CZH proteins: A new family of Rho-GEFs. J. Cell Sci. 118, 4937-4946 (2005).
-
(2005)
J. Cell Sci.
, vol.118
, pp. 4937-4946
-
-
Meller, N.1
Merlot, S.2
Guda, C.3
-
13
-
-
53249143863
-
DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells
-
G. Gadea, V. Sanz-Moreno, A. Self, A. Godi, C. J. Marshall, DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells. Curr. Biol. 18, 1456-1465 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 1456-1465
-
-
Gadea, G.1
Sanz-Moreno, V.2
Self, A.3
Godi, A.4
Marshall, C.J.5
-
14
-
-
54549088877
-
Rac activation and inactivation control plasticity of tumor cell movement
-
V. Sanz-Moreno, G. Gadea, J. Ahn, H. Paterson, P. Marra, S. Pinner, E. Sahai, C. J. Marshall, Rac activation and inactivation control plasticity of tumor cell movement. Cell 135, 510-523 (2008).
-
(2008)
Cell
, vol.135
, pp. 510-523
-
-
Sanz-Moreno, V.1
Gadea, G.2
Ahn, J.3
Paterson, H.4
Marra, P.5
Pinner, S.6
Sahai, E.7
Marshall, C.J.8
-
15
-
-
23144450821
-
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
-
J. F. Cote, A. B. Motoyama, J. A. Bush, K. Vuori, A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling. Nat. Cell Biol. 7, 797-807 (2005).
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 797-807
-
-
Cote, J.F.1
Motoyama, A.B.2
Bush, J.A.3
Vuori, K.4
-
16
-
-
70249105718
-
Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor
-
J. Yang, Z. Zhang, S. M. Roe, C. J. Marshall, D. Barford, Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science 325, 1398-1402 (2009).
-
(2009)
Science
, vol.325
, pp. 1398-1402
-
-
Yang, J.1
Zhang, Z.2
Roe, S.M.3
Marshall, C.J.4
Barford, D.5
-
17
-
-
0033179296
-
GEFs: Structural basis for their activation of small GTP-binding proteins
-
J. Cherfils, P. Chardin, GEFs: Structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24, 306-311 (1999).
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 306-311
-
-
Cherfils, J.1
Chardin, P.2
-
18
-
-
0032560850
-
The structural basis of the activation of Ras by Sos
-
P. A. Boriack-Sjodin, S. M. Margarit, D. Bar-Sagi, J. Kuriyan, The structural basis of the activation of Ras by Sos. Nature 394, 337-343 (1998).
-
(1998)
Nature
, vol.394
, pp. 337-343
-
-
Boriack-Sjodin, P.A.1
Margarit, S.M.2
Bar-Sagi, D.3
Kuriyan, J.4
-
19
-
-
0034619877
-
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
-
D. K. Worthylake, K. L. Rossman, J. Sondek, Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. Nature 408, 682-688 (2000).
-
(2000)
Nature
, vol.408
, pp. 682-688
-
-
Worthylake, D.K.1
Rossman, K.L.2
Sondek, J.3
-
20
-
-
0035917523
-
Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)
-
L. Renault, J. Kuhlmann, A. Henkel, A. Wittinghofer, Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell 105, 245-255 (2001).
-
(2001)
Cell
, vol.105
, pp. 245-255
-
-
Renault, L.1
Kuhlmann, J.2
Henkel, A.3
Wittinghofer, A.4
-
21
-
-
0348047597
-
Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism
-
E. Mossessova, R. A. Corpina, J. Goldberg, Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism. Mol. Cell 12, 1403-1411 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 1403-1411
-
-
Mossessova, E.1
Corpina, R.A.2
Goldberg, J.3
-
22
-
-
0346243924
-
Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
-
L. Renault, B. Guibert, J. Cherfils, Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor. Nature 426, 525-530 (2003).
-
(2003)
Nature
, vol.426
, pp. 525-530
-
-
Renault, L.1
Guibert, B.2
Cherfils, J.3
-
23
-
-
33846027894
-
Structural evidence for a common intermediate in small G protein-GEF reactions
-
C. Thomas, I. Fricke, A. Scrima, A. Berken, A. Wittinghofer, Structural evidence for a common intermediate in small G protein-GEF reactions. Mol. Cell 25, 141-149 (2007).
-
(2007)
Mol. Cell
, vol.25
, pp. 141-149
-
-
Thomas, C.1
Fricke, I.2
Scrima, A.3
Berken, A.4
Wittinghofer, A.5
-
24
-
-
42749086991
-
The role of the conserved switch II glutamate in guanine nucleotide exchange factormediated nucleotide exchange of GTP-binding proteins
-
R. Gasper, C. Thomas, M. R. Ahmadian, A. Wittinghofer, The role of the conserved switch II glutamate in guanine nucleotide exchange factormediated nucleotide exchange of GTP-binding proteins. J. Mol. Biol. 379, 51-63 (2008).
-
(2008)
J. Mol. Biol.
, vol.379
, pp. 51-63
-
-
Gasper, R.1
Thomas, C.2
Ahmadian, M.R.3
Wittinghofer, A.4
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