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Volumn 115, Issue 3, 2010, Pages 667-676

Src tyrosine kinase preactivation is associated with platelet hypersensitivity in essential thrombocythemia and polycythemia vera

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; HYDROXYUREA; JANUS KINASE 2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; THROMBIN; WARFARIN; JAK2 PROTEIN, HUMAN;

EID: 77449127290     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-12-196535     Document Type: Article
Times cited : (15)

References (50)
  • 9
    • 38549135526 scopus 로고    scopus 로고
    • Influence of Jak2V617 allele burden on phenotype in essential thrombocythemia
    • Antonioli E, Guglielmelli P, Poli G, et al. Influence of Jak2V617 allele burden on phenotype in essential thrombocythemia. Haematologica. 2008; 93(1):41-48.
    • (2008) Haematologica , vol.93 , Issue.1 , pp. 41-48
    • Antonioli, E.1    Guglielmelli, P.2    Poli, G.3
  • 10
    • 33745700689 scopus 로고    scopus 로고
    • The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia
    • Bellucci S, Michiels JJ. The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia. Semin Thromb Hemost. 2006;32(4 pt 2):381-398.
    • (2006) Semin Thromb Hemost , vol.32 , Issue.4 PART 2 , pp. 381-398
    • Bellucci, S.1    Michiels, J.J.2
  • 11
    • 33646484482 scopus 로고    scopus 로고
    • Platelets and thrombosis in myeloproliferative diseases
    • Harrison CN. Platelets and thrombosis in myeloproliferative diseases. Hematology Am Soc Hematol Educ Program. 2005;409-415.
    • (2005) Hematology Am Soc Hematol Educ Program , pp. 409-415
    • Harrison, C.N.1
  • 12
    • 0027340192 scopus 로고
    • Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets
    • Clark EA, Brugge JS. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets. Mol Cell Biol. 1993;13(3):1863-1871.
    • (1993) Mol Cell Biol , vol.13 , Issue.3 , pp. 1863-1871
    • Clark, E.A.1    Brugge, J.S.2
  • 13
    • 0037092048 scopus 로고    scopus 로고
    • Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton
    • Obergfell A, Eto K, Mocsai A, et al. Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. J Cell Biol. 2002;157(2):265-275.
    • (2002) J Cell Biol , vol.157 , Issue.2 , pp. 265-275
    • Obergfell, A.1    Eto, K.2    Mocsai, A.3
  • 14
    • 33750969720 scopus 로고    scopus 로고
    • PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]i: Evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets
    • Harper MT, Sage SO. PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]i: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets. J Thromb Haemost. 2006;4(12): 2695-2703.
    • (2006) J Thromb Haemost , vol.4 , Issue.12 , pp. 2695-2703
    • Harper, M.T.1    Sage, S.O.2
  • 16
    • 0029896163 scopus 로고    scopus 로고
    • Regulation, substrates and functions of src
    • Brown MT, Cooper JA. Regulation, substrates and functions of src. Biochim Biophys Acta. 1996; 1287(2-3):121-149.
    • (1996) Biochim Biophys Acta , vol.1287 , Issue.2-3 , pp. 121-149
    • Brown, M.T.1    Cooper, J.A.2
  • 17
    • 33750076068 scopus 로고    scopus 로고
    • The role of Src in solid and hematologic malignancies: Development of new-generation Src inhibitors
    • Alvarez RH, Kantarjian HM, Cortes JE. The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors. Cancer. 2006;107(8):1918-1929.
    • (2006) Cancer , vol.107 , Issue.8 , pp. 1918-1929
    • Alvarez, R.H.1    Kantarjian, H.M.2    Cortes, J.E.3
  • 18
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7): 2292-2302.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 19
    • 33751161677 scopus 로고    scopus 로고
    • Pediatric patients with essential thrombocythemia are mostly polyclonal and V617Jak2 negative
    • Randi ML, Putti MC, Scapin M, et al. Pediatric patients with essential thrombocythemia are mostly polyclonal and V617Jak2 negative. Blood. 2006;108(10):3600-3602.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3600-3602
    • Randi, M.L.1    Putti, M.C.2    Scapin, M.3
  • 20
    • 33646406275 scopus 로고    scopus 로고
    • Relation between Jak2 (V617F) mutation status, granulocytes activation, and costitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders
    • Passamonti F, Rumi E, Pietra D, et al. Relation between Jak2 (V617F) mutation status, granulocytes activation, and costitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Blood. 2006;107(9):3676-3682.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3676-3682
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 22
    • 38349183667 scopus 로고    scopus 로고
    • Serotonin (5-HT) transport in human platelets is modulated by Srccatalysed Tyr-phosphorylation of the plasma membrane transporter SERT
    • Zarpellon A, Donella-Deana A, Folda A, Turetta L, Pavanetto M, Deana R. Serotonin (5-HT) transport in human platelets is modulated by Srccatalysed Tyr-phosphorylation of the plasma membrane transporter SERT. Cell Physiol Biochem. 2008;21(1-3):87-94.
    • (2008) Cell Physiol Biochem , vol.21 , Issue.1-3 , pp. 87-94
    • Zarpellon, A.1    Donella-Deana, A.2    Folda, A.3    Turetta, L.4    Pavanetto, M.5    Deana, R.6
  • 23
    • 0034663190 scopus 로고    scopus 로고
    • Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: Identification of primary and secondary phosphorylation sites
    • Brunati AM, Bordin L, Clari G, et al. Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites. Blood. 2000;96(4):1550-1557. (Pubitemid 30658490)
    • (2000) Blood , vol.96 , Issue.4 , pp. 1550-1557
    • Brunati, A.M.1    Bordin, L.2    Clari, G.3    James, P.4    Quadroni, M.5    Baritono, E.6    Pinna, L.A.7    Donella-Deana, A.8
  • 25
    • 0036659906 scopus 로고    scopus 로고
    • Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytes
    • DOI 10.1182/blood.V100.1.276
    • Bordin L, Brunati AM, Donella-Deana A, Baggio B, Toninello A, Clari G. "Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytes" Blood. 2002;100(1):276-282. (Pubitemid 35177457)
    • (2002) Blood , vol.100 , Issue.1 , pp. 276-282
    • Bordin, L.1    Brunati, A.M.2    Donella-Deana, A.3    Baggio, B.4    Toninello, A.5    Clari, G.6
  • 26
    • 0032227241 scopus 로고    scopus 로고
    • A novel thrombopoietin signaling defect in polycythemia vera platelets
    • Moliterno AR, Siebel KE, Sun AY, Hankins WD, Spivak JL. A novel thrombopoietin signaling defect in polycythemia vera platelets. Stem Cells. 1998;16(suppl 2):185-192.
    • (1998) Stem Cells , vol.16 , Issue.SUPPL. 2 , pp. 185-192
    • Moliterno, A.R.1    Siebel, K.E.2    Sun, A.Y.3    Hankins, W.D.4    Spivak, J.L.5
  • 27
    • 2642609475 scopus 로고    scopus 로고
    • Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
    • DOI 10.1056/NEJM199802263380903
    • Moliterno AR, Hankins WD, Spivak JL. Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera. N Engl J Med. 1998;338(9):572-580. (Pubitemid 28114645)
    • (1998) New England Journal of Medicine , vol.338 , Issue.9 , pp. 572-580
    • Moliterno, A.R.1    David Hankins, W.2    Spivak, J.L.3
  • 28
    • 33845239214 scopus 로고    scopus 로고
    • Molecular mimicry in the chronic myeloproliferative disorders: Reciprocity between quantitative JAK2 V617F and Mpl expression
    • Moliterno AR, Williams DM, Rogers O, Spivak JL. Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression. Blood. 2006; 108(12):3913-3915.
    • (2006) Blood , vol.108 , Issue.12 , pp. 3913-3915
    • Moliterno, A.R.1    Williams, D.M.2    Rogers, O.3    Spivak, J.L.4
  • 30
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinase inhibitors: An update
    • DOI 10.1042/BJ20021535
    • Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: an update. Biochem J. 2003;371(pt 1):199-204. (Pubitemid 36458094)
    • (2003) Biochemical Journal , vol.371 , Issue.1 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 31
    • 34347207060 scopus 로고    scopus 로고
    • SFK-STAT pathway: An alternative and important way to malignancies
    • DOI 10.1196/annals.1377.002, Integrated Molecular Medicine for Neuronal and Neoplastic Disorders
    • Hayakawa F, Naoe T. SFK-STAT pathway: an alternative and important way to malignancies. Ann N Y Acad Sci. 2006;1086:213-222. (Pubitemid 47084370)
    • (2006) Annals of the New York Academy of Sciences , vol.1086 , pp. 213-222
    • Hayakawa, F.1    Naoe, T.2
  • 32
    • 33646414171 scopus 로고    scopus 로고
    • Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells
    • Zeuner A, Pedini F, Signore M, et al. Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells. Blood. 2006;107(9):3495-3502.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3495-3502
    • Zeuner, A.1    Pedini, F.2    Signore, M.3
  • 33
    • 17444374230 scopus 로고    scopus 로고
    • Src kinase regulation by phosphorylation and dephosphorylation
    • DOI 10.1016/j.bbrc.2005.03.012
    • Roskoski R. Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun. 2005;331(1):1-14. (Pubitemid 40545134)
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , Issue.1 , pp. 1-14
    • Roskoski Jr., R.1
  • 34
    • 19344362869 scopus 로고    scopus 로고
    • Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis
    • Paling NR, Welham MJ. Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis. Blood. 2005;105(11): 4290-4297.
    • (2005) Blood , vol.105 , Issue.11 , pp. 4290-4297
    • Paling, N.R.1    Welham, M.J.2
  • 35
    • 0035865690 scopus 로고    scopus 로고
    • Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development
    • DOI 10.1182/blood.V97.4.911
    • Qu CK, Nguyen S, Chen J, Feng GS. Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development. Blood. 2001;97(4):911-914. (Pubitemid 32154273)
    • (2001) Blood , vol.97 , Issue.4 , pp. 911-914
    • Qu, C.-K.1    Nguyen, S.2    Chen, J.3    Feng, G.-S.4
  • 36
    • 0032548830 scopus 로고    scopus 로고
    • Crystal structure of the tyrosine phosphatase SHP-2
    • DOI 10.1016/S0092-8674(00)80938-1
    • Hof P, Pluskey S, Dhe-Paganon S, Eck MJ, Shoelson SE. Crystal structure of the tyrosine phosphatase SHP-2. Cell. 1998;92(4):441-450. (Pubitemid 28101108)
    • (1998) Cell , vol.92 , Issue.4 , pp. 441-450
    • Hof, P.1    Pluskey, S.2    Dhe-Paganon, S.3    Eck, M.J.4    Shoelson, S.E.5
  • 40
    • 40549094646 scopus 로고    scopus 로고
    • Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia
    • Konieczna I, Horvath E, Wang H, et al. Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia. J Clin Invest. 2008; 118(3):853-867.
    • (2008) J Clin Invest , vol.118 , Issue.3 , pp. 853-867
    • Konieczna, I.1    Horvath, E.2    Wang, H.3
  • 42
    • 0028851764 scopus 로고
    • Translocation of cortactin (p80/85) to the actinbased cytoskeleton during thrombin receptormediated platelet activation
    • Ozawa K, Kashiwada K, Takahashi M, Sobue K. Translocation of cortactin (p80/85) to the actinbased cytoskeleton during thrombin receptormediated platelet activation. Exp Cell Res. 1995; 221(1):197-204.
    • (1995) Exp Cell Res , vol.221 , Issue.1 , pp. 197-204
    • Ozawa, K.1    Kashiwada, K.2    Takahashi, M.3    Sobue, K.4
  • 43
    • 33749028699 scopus 로고    scopus 로고
    • The paradox of platelet activation and impaired function: Platelet-von Willebrand factor interactions, and the etiology of thrombotic and hemorrhagic manifestations in essential thrombocythemia and polycythemia vera
    • DOI 10.1055/s-2006-949664
    • Michiels JJ, Berneman Z, Schroyens W, Finazzi G, Budde U, van Vliet HH. The paradox of platelet activation and impaired function: platelet-von Willebrand factor interactions, and the etiology of thrombotic and hemorrhagic manifestations in essential thrombocythemia and polycythemia vera. Semin Thromb Hemost. 2006;32(6):589-604. (Pubitemid 44453020)
    • (2006) Seminars in Thrombosis and Hemostasis , vol.32 , Issue.6 , pp. 589-604
    • Michiels, J.J.1    Berneman, Z.2    Schroyens, W.3    Finazzi, G.4    Budde, U.5    Van Vliet, H.H.D.M.6
  • 45
    • 48749127220 scopus 로고    scopus 로고
    • Hypercoagulability and tissue factor gene upregulation in hematologic malignancies
    • Falanga A, Barbui T, Rickles FR. Hypercoagulability and tissue factor gene upregulation in hematologic malignancies. Semin Thromb Hemost. 2008;34(2):204-210.
    • (2008) Semin Thromb Hemost , vol.34 , Issue.2 , pp. 204-210
    • Falanga, A.1    Barbui, T.2    Rickles, F.R.3
  • 46
    • 33646565045 scopus 로고    scopus 로고
    • Shear induces a unique series of morphological changes in translocating platelets: Effects of morphology on translocation dynamics
    • Maxwell MJ, Dopheide SM, Turner SJ, Jackson SP. Shear induces a unique series of morphological changes in translocating platelets: effects of morphology on translocation dynamics. Arterioscler Thromb Vasc Biol. 2006;26(3):663-669.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.3 , pp. 663-669
    • Maxwell, M.J.1    Dopheide, S.M.2    Turner, S.J.3    Jackson, S.P.4
  • 48
    • 2442690282 scopus 로고    scopus 로고
    • Molecular and biochemical basis for the platelet dysfunction in myeloproliferative disorders
    • Rao AK. Molecular and biochemical basis for the platelet dysfunction in myeloproliferative disorders. Semin Hematol. 2004;41(2 suppl 3):6-9.
    • (2004) Semin Hematol , vol.41 , Issue.2 SUPPL. 3 , pp. 6-9
    • Rao, A.K.1
  • 49
    • 58149350314 scopus 로고    scopus 로고
    • Activation loop tyrosines allow the JAK2(V617F) mutant to attain hyperactivation
    • Kundrapu K, Colenberg L, Duhé RJ. Activation loop tyrosines allow the JAK2(V617F) mutant to attain hyperactivation. Cell Biochem Biophys. 2008;52(2):103-112.
    • (2008) Cell Biochem Biophys , vol.52 , Issue.2 , pp. 103-112
    • Kundrapu, K.1    Colenberg, L.2    Duhé, R.J.3
  • 50
    • 33746858555 scopus 로고    scopus 로고
    • JAK2V617F mutation in platelets from essential thrombocythemia patients: Correlation with clinical features and analysis of STAT5 phosphorylation status
    • Heller PG, Lev PR, Salim JP, et al. JAK2V617F mutation in platelets from essential thrombocythemia patients: correlation with clinical features and analysis of STAT5 phosphorylation status. Eur J Haematol. 2006;77(3):210-216.
    • (2006) Eur J Haematol , vol.77 , Issue.3 , pp. 210-216
    • Heller, P.G.1    Lev, P.R.2    Salim, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.