Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats

BMC Pharmacology

Volumn 9, Issue , 2009, Pages

  Schweitzer, Alain ^a   Hasler Nguyen, Nathalie ^b   Zijlstra, Jacob ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Novartis Consumer Health ^*  (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; CARRAGEENAN; DICLOFENAC; DRUG METABOLITE; NONSTEROID ANTIINFLAMMATORY AGENT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CARCASS; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG RETENTION; DRUG STRUCTURE; DRUG TISSUE LEVEL; DRUG UPTAKE; FOOT PAD; HINDLIMB; INFLAMMATORY DISEASE; ISOTOPE LABELING; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE SECTION; WHOLE BODY AUTORADIOGRAPHY; ANIMAL; AUTORADIOGRAPHY; CHEMICALLY INDUCED DISORDER; INFLAMMATION; LONG EVANS RAT; TIME; TISSUE DISTRIBUTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AUTORADIOGRAPHY; CARRAGEENAN; DICLOFENAC; INFLAMMATION; MALE; RATS; RATS, LONG-EVANS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 63649134382     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-9-5     Document Type: Article

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