Phosphatidylserine translocation in human spermatozoa from impaired spermatogenesis

Reproductive BioMedicine Online

Volumn 19, Issue 6, 2009, Pages 770-777

  Almeida, C ^a   Sousa, M ^a,b   Barros, A ^a,b  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Anejaculation; Annexin V; Azoospermia; Human sperm apoptosis; Oligozoospermia

Indexed keywords

DIAGNOSTIC AGENT; LIPOCORTIN 5; PHOSPHATIDYLSERINE;

APOPTOSIS; ARTICLE; HUMAN; MALE; MALE INFERTILITY; METABOLISM; OLIGOSPERMIA; PATHOLOGY; PATHOPHYSIOLOGY; SPERMATOZOON;

ANNEXIN A5; APOPTOSIS; HUMANS; INFERTILITY, MALE; MALE; OLIGOSPERMIA; PHOSPHATIDYLSERINES; SPERMATOZOA;

EID: 77449113329     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2009.10.002     Document Type: Article

References (40)

1. Almeida C, Cardoso MF, Sousa M et al. 2005 Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality. Human Reproduction 20, 1307-1313.
2. Alvarez JG 2005 Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular sperm. Human Reproduction 20, 2031-2032, author reply 2032-2033.
3. Alvarez JG 2003 Nurture vs Nature: how can we optimize sperm quality? Journal of Andrology 24, 640-648.
4. Barroso G, Taylor S, Morshedi M et al. 2006 Mitochondrial membrane potential integrity and plasma membrane translocation of phosphatidylserine as early apoptotic markers: a comparison of two different sperm populations. Fertility and Sterility 85, 149-154.
5. Barroso G, Morshedi M, Oehninger S 2000 Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa. Human Reproduction 15, 1338-1344.
6. Eguchi J, Koji T, Nomata K et al. 2002 Fas-Fas ligand system as a possible mediator of spermatogenic cell apoptosis in human maturation-arrested testes. Human Cell 15, 61-68.
7. Ferrás C, Fernandes S, Marques CJ et al. 2004 AZF and DAZ gene copy-specific deletion analysis in maturation arrest and Sertoli cell-only syndrome. Molecular Human Reproduction 10, 755-761.
8. Francavilla S, D'Abrizio P, Cordeschi G et al. 2002 Fas expression correlates with human germ cell degeneration in meiotic and post-meiotic arrest of spermatogenesis. Molecular Human Reproduction 8, 213-220.
9. Francavilla S, D'Abrizio P, Rucci N et al. 2000 Fas and Fas ligand expression in fetal and adult human testis with normal or deranged spermatogenesis. Journal of Clinical Endocrinology and Metabolism 85, 2692-2700.
10. Greco E, Scarselli F, Iacobelli M et al. 2005 Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa. Human Reproduction 20, 226-230.
11. Kierszenbaum AL 2001 Apoptosis during spermatogenesis: the thrill of being alive. Molecular Reproduction and Development 58, 1-3.
12. Kim SK, Yoon YD, Park YS et al. 2007 Involvement of the Fas- Fas ligand system and active caspase-3 in abnormal apoptosis in human testes with maturation arrest and Sertoli cell-only syndrome. Fertility and Sterility 87, 547-553.
13. Lachaud C, Tesarik J, Cañadas ML, Mendoza C 2004 Apoptosis and necrosis in human ejaculated spermatozoa. Human Reproduction 19, 607-610.
14. Lin WW, Lamb DJ, Wheeler TM et al. 1997 In situ end-labelling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis. Fertility and Sterility 68, 1065-1069.
15. Marchetti C, Gallego MA, Defossez A et al. 2004 Staining of human sperm with fluorochrome-labelled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameters. Human Reproduction 19, 1127-1134.
16. Martin G, Sabido O, Durand P, Levy R et al. 2005 Phosphatidylserine externalization in human sperm induced by calcium ionophore A23187: relationship with apoptosis, membrane scrambling and the acrosome reaction. Human Reproduction 20, 3459-3468.
17. Martin SJ, Reutelingsperger CP, McGahon AJ et al. 1995 Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. Journal of Experimental Medicine 182, 1545-1556.
18. Naito M, Nagashima K, Mashima T, Tsuruo T et al. 1997 Phosphatidylserine externalization is a downstream event of Interleukin-1b-Converting enzyme family protease activation during apoptosis. Blood 89, 2060-2066.
19. Nakanishi Y, Shiratsuchi A 2004 Phagocytic removal of apoptotic spermatogenic cells by Sertoli cells: mechanisms and consequences. Biological and Pharmaceutical Bulletin 27, 13-16.
20. Oosterhuis GJ, Mulder AB, Kalsbeek-Batenburg E et al. 2000 Measuring apoptosis in human spermatozoa: a biological assay for semen quality. Fertility and Sterility 74, 245-250.
21. Pentikainen V, Erkkila K, Dunkel L 1999 Fas regulates germ cell apoptosis in the human testis in vitro. American Journal of Physiology 276, E310-E316.
22. Pinho MJ, Neves R, Costa P et al. 2005 Unique t(Y;1)(q12;q12) reciprocal translocation with loss of the heterochromatic region of chromosome 1 in a male with azoospermia due to meiotic arrest: a case report. Human Reproduction 20, 689-696.
23. Print CG, Loveland KL 2000 Germ cell suicide: new insights into apoptosis during spermatogenesis. Bioessays 22, 423-430.
24. Ramos L, Kleingeld P, Meuleman E et al. 2002 Assessment of DNA fragmentation of spermatozoa that were surgically retrieved from men with obstructive azoospermia. Fertility and Sterility 77, 233-237.
25. Ricci G, Perticarari S, Fragonas E et al. 2002 Apoptosis in human sperm: its correlation with semen quality and the presence of leukocytes. Human Reproduction 17, 2665-2672.
26. Rodriguez I, Ody C, Araki K, Garcia I, Vassalli P et al. 1997 An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO Journal 16, 2262-2270.
27. Shen HM, Dai J, Chia SE, Lim A, Ong CN et al. 2002 Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality. Human Reproduction 17, 1266-1273.
28. Shiratsuchi A, Umeda M, Ohba Y, Nakanishi Y et al. 1997 Recognition of phosphatidylserine on the surface of apoptotic spermatogenic cells and subsequent phagocytosis by Sertoli cells of the rat. Journal of Biological Chemistry 272, 2354-2358.
29. Sousa M, Cremades N, Silva J et al. 2002 Predictive value of testicular histology in secretory azoospermic subgroups and clinical outcome after microinjection of fresh and frozen-thawed sperm and spermatids. Human Reproduction 17, 1800-1810.
30. Takagi S, Itoh N, Kimura M, Sasao T, Tsukamoto T et al. 2001 Spermatogonial proliferation and apoptosis in hypospermatogenesis associated with nonobstructive azoospermia. Fertility and Sterility 76, 901-907.
31. Taylor SL, Weng SL, Fox P et al. 2004 Somatic cell apoptosis markers and pathways in human ejaculated sperm: potential utility as indicators of sperm quality. Molecular Human Reproduction 10, 825-834.
32. Tesarik J, Ubaldi F, Rienzi L et al. 2004 Caspase-dependent and -independent DNA fragmentation in Sertoli and germ cells from men with primary testicular failure: relationship with histological diagnosis. Human Reproduction 2, 254-261.
33. Tesarik J, Greco E, Mendoza C 2001 Assisted reproduction with in-vitro-cultured testicular spermatozoa in cases of severe germ cell apoptosis: a pilot study. Human Reproduction 16, 2640-2645.
34. Tesarik J, Greco E, Cohen-Bacrie P, Mendoza C et al. 1998 Germ cell apoptosis in men with complete and incomplete spermiogenesis failure. Molecular Human Reproduction 4, 757-762.
35. Van den Eijnde SM, Boshart L, Reutelingsperger CP et al. 1997 Phosphatidylserine plasma membrane asymmetry in vivo: a pancellular phenomenon which alters during apoptosis. Cell Death and Differentiation 4, 311-316.
36. Van Engeland M, Nieland LJ, Ramaekers FC et al. 1998 Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31, 1-9.
37. Varum S, Bento C, Sousa AP et al. 2007 Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers. Fertility and Sterility 87, 572-583.
38. Wang X, Sharma RK, Sikka SC et al. 2003 Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility. Fertility and Sterility 80, 531-535.
39. Weng SL, Taylor SL, Morshedi M et al. 2002 Caspase activity and apoptotic markers in ejaculated human sperm. Molecular Human Reproduction 8, 984-991.
40. World Health Organization 1999 Laboratory Manual for the Examination of Human Semen and Sperm Cervical Mucus Interaction. Cambridge University Press, UK.