Spermatogonial proliferation and apoptosis in hypospermatogenesis associated with nonobstructive azoospermia

Fertility and Sterility

Volumn 76, Issue 5, 2001, Pages 901-907

  Takagi, Seiji ^a   Itoh, Naoki ^a   Kimura, Makoto ^a   Sasao, Takumi ^a   Tsukamoto, Taiji ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Cell proliferation; Hypospermatogenesis; Spermatogonia

Indexed keywords

CYCLINE;

APOPTOSIS; AZOOSPERMIA; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE CLASSIFICATION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NICK END LABELING; OLIGOSPERMIA; PRIORITY JOURNAL; SPERMATOGENESIS; SPERMATOGONIUM;

ADULT; APOPTOSIS; CELL DIVISION; HUMANS; INFERTILITY, MALE; MALE; OLIGOSPERMIA; PROLIFERATING CELL NUCLEAR ANTIGEN; RETROSPECTIVE STUDIES; SPERMATOGENESIS; SPERMATOGONIA;

EID: 0034768213     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)02732-7     Document Type: Conference Paper

References (22)

1. Meistrich ML. Effects of chemotherapy and radiotherapy on spermatogenesis. Eur Urol 1993;23:136-42.
2. Bustos-Obregon E, Rodriguez H. Testicular x-ray irradiation in adult mice as a model to study spermatogonial proliferation. Andrologia 1991;23:447-50.
3. Judas L, Bentzen SM, Hansen PV, Overgaard J. Proliferative response of mouse spermatogonial stem cells after irradiation: a quantitative model analysis of experimental data. Cell Prolif 1996;29:73-87.
4. Raff MC. Social controls on cell survival and cell death. Nature 1992;356:397-400.
5. Hall PA, Levison DA. Review: assessment of cell proliferation in histological material. J Clin Pathol 1990;43:184-92.
6. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
7. Makler A. A new chamber for rapid sperm count and motility estimation. Fertil Steril 1978;30:313-8.
8. Itoh N, Kumamoto Y, Maruta H, Takagi Y, Mikuma N, Nanbu A, et al. Determination of the normal range of serum LH and FSH levels in normal adult males - comparison with IRMA and RIA. Folia Endocrinol 1990;66:572-83.
9. Manova K, Huang EJ, Angeles M, De Leon V, Sanchez S, Pronovost SM, et al. The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia. Dev Biol 1993;157:85-99.
10. Yoshinaga K, Nishikawa S, Ogawa M, Hayashi SI, Kunisada T, Fujimoto T, et al. Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and function. Development 1991;113:689-99.
11. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-62.
12. Rodriguez JB, Garcia CM. Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: re-evaluation of cell types that exhibit the ability to die during spermatogenesis. Cell Prolif 1996;29: 13-31.
13. Henriksen K, Kulmala J, Toppari J, Mehrotra K, Parvinen M. Stage-specific apoptosis in the rat seminiferous epithelium: quantification of irradiation effects. J Androl 1996;17:394-402.
14. Richburg JH, Boekelheide K. Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes. Toxicol Appl Pharmacol 1996;137:42-50.
15. Hikim APS, Wang C, Leung A, Swerdloff RS. Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment. Endocrinology 1995; 136:2770-5.
16. Yin Y, Hawkins KL, Dewolf WC, Morgentaler A. Heat stress causes testicular germ cell apoptosis in adult mice. J Androl 1997;18:159-65.
17. Rodriguez JB, Garcia CM. Mild hypothermia induces apoptosis in rat testis at specific stages of the seminiferous epithelium. J Androl 1997; 18:535-9.
18. Lin WW, Lipshultz LI, Lamb DJ, Kim ED, Wheeler TM. In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis. Fertil Steril 1997;68: 1065-9.
19. Furuchi T, Masuko K, Nishimune Y, Obinata M, Matsui Y. Inhibition of testicular germ cell apoptosis and differentiation in mice misexpressing bcl-2 in spermatogonia. Development 1996;122:1703-9.
20. Knudson CM, Tung KSK, Tourtellotte WG, Brown GAJ, Korsmeyer SJ. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 1995;270:96-9.
21. Foresta C, Bettella A, Ferlin A, Garolla A, Rossato M. Evidence for a stimulatory role of follicle-stimulating hormone on the spermatogonial population in adult males. Fertil Steril 1997;69:636-42.
22. De Rooij DG, Van Dissel-Emiliani FMF, Van Pelt AMM. Regulation of spermatogonial proliferation. Ann NY Acad Sci 1989;564:140-53.