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Volumn 12, Issue 11, 2004, Pages 924-934

Molecular phenotyping of HCS-2/8 cells as an in vitro model of human chondrocytes

Author keywords

Cartilage; Cell line; Chondrocyte; Chondrosarcoma; Matrix

Indexed keywords

AGGRECAN; ALGINIC ACID; COLLAGEN; COMPLEMENTARY DNA; MESSENGER RNA;

EID: 7744234055     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.08.002     Document Type: Article
Times cited : (15)

References (30)
  • 1
    • 0034966785 scopus 로고    scopus 로고
    • Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritic human articular knee cartilage: A study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage
    • T. Aigner M. Hemmel D. Neureiter P.M. Gebhard G. Zeiler T. Kirchner et al. Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritic human articular knee cartilage: A study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage Arthritis Rheum 44 2001 1304-1312
    • (2001) Arthritis Rheum. , vol.44 , pp. 1304-1312
    • Aigner, T.1    Hemmel, M.2    Neureiter, D.3    Gebhard, P.M.4    Zeiler, G.5    Kirchner, T.6
  • 2
    • 0018221370 scopus 로고
    • Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture
    • P.D. Benya S.R. Padilla M.E. Nimni Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture Cell 15 1978 1313-1321
    • (1978) Cell , vol.15 , pp. 1313-1321
    • Benya, P.D.1    Padilla, S.R.2    Nimni, M.E.3
  • 3
    • 0017723046 scopus 로고
    • Relationship between cell shape and type of collagen synthesized as chondrocytes lose their cartilage phenotype in culture
    • K. von der Mark V. Gauss H. von der Mark P.K. Müller Relationship between cell shape and type of collagen synthesized as chondrocytes lose their cartilage phenotype in culture Nature 267 1977 531-532
    • (1977) Nature , vol.267 , pp. 531-532
    • von der Mark, K.1    Gauss, V.2    von der Mark, H.3    Müller, P.K.4
  • 4
    • 0036166257 scopus 로고    scopus 로고
    • Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis
    • D.G. Stokes G. Liu I.B. Coimbra S. Velazquez R.M. Crowl S.A. Jimenez Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis Arthritis Rheum 46 2002 404-419
    • (2002) Arthritis Rheum. , vol.46 , pp. 404-419
    • Stokes, D.G.1    Liu, G.2    Coimbra, I.B.3    Velazquez, S.4    Crowl, R.M.5    Jimenez, S.A.6
  • 5
    • 0024411080 scopus 로고
    • Establishment of a clonal human chondrosarcoma cell line with cartilage phenotypes
    • M. Takigawa K. Tajima H.-O. Pan M. Enomoto A. Kinoshita F. Suzuki et al. Establishment of a clonal human chondrosarcoma cell line with cartilage phenotypes Cancer Res 49 1989 3996-4002
    • (1989) Cancer Res. , vol.49 , pp. 3996-4002
    • Takigawa, M.1    Tajima, K.2    Pan, H.-O.3    Enomoto, M.4    Kinoshita, A.5    Suzuki, F.6
  • 6
    • 0032577703 scopus 로고    scopus 로고
    • Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis
    • C.M. Simbulan-Rosenthal D.S. Rosenthal S. Iyer A.H. Boulares M.E. Smulson Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis J Biol Chem 273 1998 13703-13712
    • (1998) J. Biol. Chem. , vol.273 , pp. 13703-13712
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Iyer, S.3    Boulares, A.H.4    Smulson, M.E.5
  • 7
    • 0022058201 scopus 로고
    • Detection by the PAP technique of lysozyme-containing synoviocytes and their quantity in rheumatoid and osteoarthritis
    • G. Geiler U. Riedel Detection by the PAP technique of lysozyme-containing synoviocytes and their quantity in rheumatoid and osteoarthritis Histochem J 17 1985 562-563
    • (1985) Histochem. J. , vol.17 , pp. 562-563
    • Geiler, G.1    Riedel, U.2
  • 8
    • 0029925577 scopus 로고    scopus 로고
    • Expression of c-fos gene inhibits proteoglycan synthesis in transfected chondrocyte
    • M. Tsuji S. Funahashi M. Takigawa M. Seiki K. Fujii T. Yoshida Expression of c-fos gene inhibits proteoglycan synthesis in transfected chondrocyte FEBS Lett 381 1996 222-226
    • (1996) FEBS Lett. , vol.381 , pp. 222-226
    • Tsuji, M.1    Funahashi, S.2    Takigawa, M.3    Seiki, M.4    Fujii, K.5    Yoshida, T.6
  • 9
    • 0034464865 scopus 로고    scopus 로고
    • Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture
    • T. Nakanishi T. Nishida T. Shimo K. Kobayashi T. Kubo T. Tamatani et al. Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture Endocrinology 141 2000 264-273
    • (2000) Endocrinology , vol.141 , pp. 264-273
    • Nakanishi, T.1    Nishida, T.2    Shimo, T.3    Kobayashi, K.4    Kubo, T.5    Tamatani, T.6
  • 10
    • 0032577910 scopus 로고    scopus 로고
    • Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8)
    • T. Nishida T. Nakanishi T. Shimo M. Asano T. Hattori T. Tamatani et al. Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8) Biochem Biophys Res Commun 247 1998 905-909
    • (1998) Biochem. Biophys. Res. Commun. , vol.247 , pp. 905-909
    • Nishida, T.1    Nakanishi, T.2    Shimo, T.3    Asano, M.4    Hattori, T.5    Tamatani, T.6
  • 13
    • 0034972517 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: Abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors
    • T. Sakai F. Kambe H. Mitsuyama N. Ishiguro K. Kurokouchi M. Takigawa et al. Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: Abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors J Bone Miner Res 16 2001 1272-1280
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1272-1280
    • Sakai, T.1    Kambe, F.2    Mitsuyama, H.3    Ishiguro, N.4    Kurokouchi, K.5    Takigawa, M.6
  • 14
    • 0032576992 scopus 로고    scopus 로고
    • Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8)
    • T. Hattori T. Fujisawa K. Sasaki Y. Yutani T. Nakanishi K. Takahashi et al. Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8) Biochem Biophys Res Commun 245 1998 679-683
    • (1998) Biochem. Biophys. Res. Commun. , vol.245 , pp. 679-683
    • Hattori, T.1    Fujisawa, T.2    Sasaki, K.3    Yutani, Y.4    Nakanishi, T.5    Takahashi, K.6
  • 15
    • 0026052321 scopus 로고
    • Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell cultures
    • J.A. Block S.E. Inerot S. Gitelis J.H. Kimura Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell cultures J Bone Joint Surg 73A 1991 647-658
    • (1991) J. Bone Joint Surg. , vol.73 A , pp. 647-658
    • Block, J.A.1    Inerot, S.E.2    Gitelis, S.3    Kimura, J.H.4
  • 17
    • 0036822797 scopus 로고    scopus 로고
    • Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
    • B. Bau P.M. Gebhard J. Haag T. Knorr E. Bartnik T. Aigner Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro Arthritis Rheum 46 2002 2648-2657
    • (2002) Arthritis Rheum. , vol.46 , pp. 2648-2657
    • Bau, B.1    Gebhard, P.M.2    Haag, J.3    Knorr, T.4    Bartnik, E.5    Aigner, T.6
  • 19
    • 0037255203 scopus 로고    scopus 로고
    • Quantification of expression levels of cellular differentiation markers does not support a general shift in the cellular phenotype of osteoarthritic chondrocytes
    • P.M. Gebhard A. Gehrsitz B. Bau S. Söder W. Eger T. Aigner Quantification of expression levels of cellular differentiation markers does not support a general shift in the cellular phenotype of osteoarthritic chondrocytes J Orthop Res 21 2003 96-101
    • (2003) J. Orthop. Res. , vol.21 , pp. 96-101
    • Gebhard, P.M.1    Gehrsitz, A.2    Bau, B.3    Söder, S.4    Eger, W.5    Aigner, T.6
  • 20
    • 0042889117 scopus 로고    scopus 로고
    • A comparison of statistical methods for analysis of high density oligonucleotide array data
    • D. Rajagopalan A comparison of statistical methods for analysis of high density oligonucleotide array data Bioinformatics 19 2003 1469-1476
    • (2003) Bioinformatics , vol.19 , pp. 1469-1476
    • Rajagopalan, D.1
  • 21
    • 0028227006 scopus 로고
    • Proto-oncogene expression in human chondrosarcoma cell line: HCS-2/8
    • J. Zhu H.-O. Pan F. Suzuki M. Takigawa Proto-oncogene expression in human chondrosarcoma cell line: HCS-2/8 Jpn J Cancer Res 85 1994 364-371
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 364-371
    • Zhu, J.1    Pan, H.-O.2    Suzuki, F.3    Takigawa, M.4
  • 23
    • 0041662164 scopus 로고    scopus 로고
    • Sox9 expression does not correlate with type II collagen expression in adult articular chondrocytes
    • T. Aigner P.M. Gebhard E. Schmid B. Bau V. Harley E. Pöschl Sox9 expression does not correlate with type II collagen expression in adult articular chondrocytes Matrix Biol 22 2003 363-372
    • (2003) Matrix Biol. , vol.22 , pp. 363-372
    • Aigner, T.1    Gebhard, P.M.2    Schmid, E.3    Bau, B.4    Harley, V.5    Pöschl, E.6
  • 24
    • 0028832251 scopus 로고
    • Identification of a new family of protein phosphatase 2A regulatory subunits
    • B. McCright D.M. Virshup Identification of a new family of protein phosphatase 2A regulatory subunits J Biol Chem 270 1995 26123-26128
    • (1995) J. Biol. Chem. , vol.270 , pp. 26123-26128
    • McCright, B.1    Virshup, D.M.2
  • 25
    • 0031760438 scopus 로고    scopus 로고
    • Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T)
    • D. Bachner M. Ahrens D. Schroder A. Hoffmann J. Lauber N. Betat et al. Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T) Dev Dyn 213 1998 398-411
    • (1998) Dev. Dyn. , vol.213 , pp. 398-411
    • Bachner, D.1    Ahrens, M.2    Schroder, D.3    Hoffmann, A.4    Lauber, J.5    Betat, N.6
  • 26
    • 0024210874 scopus 로고
    • Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes
    • M.B. Goldring J.R. Birkhead L.J. Sandell T. Kimura S.M. Krane Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes J Clin Invest 82 1988 2026-2037
    • (1988) J. Clin. Invest , vol.82 , pp. 2026-2037
    • Goldring, M.B.1    Birkhead, J.R.2    Sandell, L.J.3    Kimura, T.4    Krane, S.M.5
  • 27
    • 0030936759 scopus 로고    scopus 로고
    • Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage
    • T. Aigner S.I. Vornehm G. Zeiler J. Dudhia K. von der Mark M.T. Bayliss Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage Arthritis Rheum 40 1997 562-569
    • (1997) Arthritis Rheum. , vol.40 , pp. 562-569
    • Aigner, T.1    Vornehm, S.I.2    Zeiler, G.3    Dudhia, J.4    von der Mark, K.5    Bayliss, M.T.6
  • 28
    • 0037089667 scopus 로고    scopus 로고
    • Prognostic relevance of cell biologic and biochemical features in conventional chondrosarcomas
    • T. Aigner S. Muller D. Neureiter D.M. Illstrup T. Kirchner J. Bjornsson Prognostic relevance of cell biologic and biochemical features in conventional chondrosarcomas Cancer 94 2002 2273-2281
    • (2002) Cancer , vol.94 , pp. 2273-2281
    • Aigner, T.1    Muller, S.2    Neureiter, D.3    Illstrup, D.M.4    Kirchner, T.5    Bjornsson, J.6
  • 29
    • 0030907579 scopus 로고    scopus 로고
    • Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA
    • T. Nakanishi Y. Kimura T. Tamura H. Ichikawa M. Takigawa T. Sugimoto Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA Biochem Biophys Res Commun 234 1997 206-210
    • (1997) Biochem. Biophys. Res. Commun. , vol.234 , pp. 206-210
    • Nakanishi, T.1    Kimura, Y.2    Tamura, T.3    Ichikawa, H.4    Takigawa, M.5    Sugimoto, T.6
  • 30
    • 0036380586 scopus 로고    scopus 로고
    • Towards a new understanding and classification of chondrogenic neoplasias of the skeleton-biochemistry and cell biology of chondrosarcoma and its variants
    • T. Aigner Towards a new understanding and classification of chondrogenic neoplasias of the skeleton-biochemistry and cell biology of chondrosarcoma and its variants Virchows Arch 441 2002 219-230
    • (2002) Virchows Arch. , vol.441 , pp. 219-230
    • Aigner, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.