The 1.5 Å Crystal structure of a bleomycin resistance determinant from bleomycin-producing Streptomyces verticillus

Journal of Molecular Biology

Volumn 295, Issue 4, 2000, Pages 915-925

  Kawano, Yoshiaki ^a   Kumagai, Takanori ^b   Muta, Kengo ^b   Matoba, Yasuyuki ^b   Davies, Julian ^c   Sugiyama, Masanori ^b  

^a RIKEN HARIMA INSTITUTE   (Japan)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Arm exchange; Bleomycin; Bleomycin binding protein; Streptomyces verticillus; X ray crystallography

Indexed keywords

BLEOMYCIN; DRUG BINDING PROTEIN; ACYLTRANSFERASE; BACTERIAL PROTEIN; BLEOMYCIN N ACETYLTRANSFERASE; BLEOMYCIN N-ACETYLTRANSFERASE;

ARTICLE; CRYSTAL STRUCTURE; DRUG BINDING SITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RADIATION SCATTERING; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; STREPTOMYCES; STREPTOMYCES VERTICILLUS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HYDROGEN BOND; KINETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT;

ACETYLTRANSFERASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BLEOMYCIN; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, MICROBIAL; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES;

EID: 0034723074     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3404     Document Type: Article

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