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Volumn 153, Issue 2, 2010, Pages 610-618

Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia

Author keywords

Age of onset; Methylenetetrahydrofolate reductase gene (MTHFR); Schizophrenia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 77349098572     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.31030     Document Type: Article
Times cited : (33)

References (66)
  • 3
    • 0023811032 scopus 로고
    • Gender differences in age at onset of schizophrenia. An overview
    • Angermeyer MC, Kuhn L. 1988. Gender differences in age at onset of schizophrenia. An overview. Eur Arch Psychiatry Neurol Sci 237: 351-364.
    • (1988) Eur Arch Psychiatry Neurol Sci , vol.237 , pp. 351-364
    • Angermeyer, M.C.1    Kuhn, L.2
  • 6
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 7
    • 0028336764 scopus 로고
    • Age at onset in subtypes of schizophrenic disorders
    • Beratis S, Gabriel J, Hoidas S. 1994. Age at onset in subtypes of schizophrenic disorders. Schizophr Bull 20:287-296.
    • (1994) Schizophr Bull , vol.20 , pp. 287-296
    • Beratis, S.1    Gabriel, J.2    Hoidas, S.3
  • 9
    • 33749039999 scopus 로고    scopus 로고
    • Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
    • Cadieux B, Ching TT, VandenBerg SR, Costello JF. 2006. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res 66:8469-8476.
    • (2006) Cancer Res , vol.66 , pp. 8469-8476
    • Cadieux, B.1    Ching, T.T.2    VandenBerg, S.R.3    Costello, J.F.4
  • 10
    • 0035826548 scopus 로고    scopus 로고
    • Affected sibling pair linkage analysis of qualitative and quantitative traits for schizophrenia on chromosome 22 in a Chinese population
    • Cai G, Li T, Deng H, Zhao J, Hu X, Murray RM, Liu X, Sham PC, Collier DA. 2001. Affected sibling pair linkage analysis of qualitative and quantitative traits for schizophrenia on chromosome 22 in a Chinese population. Am J Med Genet 105:321-327.
    • (2001) Am J Med Genet , vol.105 , pp. 321-327
    • Cai, G.1    Li, T.2    Deng, H.3    Zhao, J.4    Hu, X.5    Murray, R.M.6    Liu, X.7    Sham, P.C.8    Collier, D.A.9
  • 11
    • 84925549046 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer
    • Campbell IG, Baxter SW, Eccles DM, Choong DY. 2002. Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer. Breast Cancer Res 4:R14.
    • (2002) Breast Cancer Res , vol.4
    • Campbell, I.G.1    Baxter, S.W.2    Eccles, D.M.3    Choong, D.Y.4
  • 16
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. 2008. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 66:87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 17
    • 36849066949 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants
    • Ellingrod VL, Miller del D, Taylor SF, Moline J, Holman T, Kerr J. 2008. Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. Schizophr Res 98: 47-54.
    • (2008) Schizophr Res , vol.98 , pp. 47-54
    • Ellingrod, V.L.1    Miller del, D.2    Taylor, S.F.3    Moline, J.4    Holman, T.5    Kerr, J.6
  • 21
    • 33845887461 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: A HuGE review
    • Gilbody S, Lewis S, Lightfoot T. 2007. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: A HuGE review. Am J Epidemiol 165:1-13.
    • (2007) Am J Epidemiol , vol.165 , pp. 1-13
    • Gilbody, S.1    Lewis, S.2    Lightfoot, T.3
  • 23
    • 24044488636 scopus 로고    scopus 로고
    • Age at onset of schizophrenia: Interaction between brain-derived neurotrophic factor and dopamine D3 receptor gene variants
    • Gourion D, Goldberger C, Leroy S, Bourdel MC, Olíe JP, Krebs MO. 2005. Age at onset of schizophrenia: Interaction between brain-derived neurotrophic factor and dopamine D3 receptor gene variants. Neuroreport 16:1407-1410.
    • (2005) Neuroreport , vol.16 , pp. 1407-1410
    • Gourion, D.1    Goldberger, C.2    Leroy, S.3    Bourdel, M.C.4    Olíe, J.P.5    Krebs, M.O.6
  • 25
    • 0027441604 scopus 로고
    • The influence of age and sex on the onset and early course of schizophrenia
    • Häfner H, Maurer K, Löffler W, Riecher-Rössler A. 1993. The influence of age and sex on the onset and early course of schizophrenia. Br J Psychiatry 162:80-86.
    • (1993) Br J Psychiatry , vol.162 , pp. 80-86
    • Häfner, H.1    Maurer, K.2    Löffler, W.3    Riecher-Rössler, A.4
  • 26
    • 33750743040 scopus 로고    scopus 로고
    • Epidermal growth factor a61g polymorphism is associated with the age of onset of schizophrenia in male patients
    • Hänninen K, Katila H, Anttila S, Rontu R, Maaskola J, Hurme M, Lehtimäki T. 2007. Epidermal growth factor a61g polymorphism is associated with the age of onset of schizophrenia in male patients. J Psychiatr Res 41:8-14.
    • (2007) J Psychiatr Res , vol.41 , pp. 8-14
    • Hänninen, K.1    Katila, H.2    Anttila, S.3    Rontu, R.4    Maaskola, J.5    Hurme, M.6    Lehtimäki, T.7
  • 32
    • 33846551159 scopus 로고    scopus 로고
    • Distribution of 1298A>C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia
    • Kempisty B, Bober A, Luczak M, Czerski P, Szczepankiewicz A, Hauser J, Jagodzinski PP. 2007. Distribution of 1298A>C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia. Eur Psychiatry 22:39-43.
    • (2007) Eur Psychiatry , vol.22 , pp. 39-43
    • Kempisty, B.1    Bober, A.2    Luczak, M.3    Czerski, P.4    Szczepankiewicz, A.5    Hauser, J.6    Jagodzinski, P.P.7
  • 33
    • 3042722158 scopus 로고    scopus 로고
    • Linkage disequlibrium in the DTNBP1 (dysbindin) gene region and on chromosome 1p36 among psychotic patients from a genetic isolate in Israel: Findings from identity by descent haplotype sharing analysis
    • Kohn Y, Danilovich E, Filon D, Oppenheim A, Karni O, Kanyas K, Turetsky N, Korner M, Lerer B. 2004. Linkage disequlibrium in the DTNBP1 (dysbindin) gene region and on chromosome 1p36 among psychotic patients from a genetic isolate in Israel: Findings from identity by descent haplotype sharing analysis. Am J Med Genet Part B 128B:65-70.
    • (2004) Am J Med Genet , vol.128 B , Issue.PART B , pp. 65-70
    • Kohn, Y.1    Danilovich, E.2    Filon, D.3    Oppenheim, A.4    Karni, O.5    Kanyas, K.6    Turetsky, N.7    Korner, M.8    Lerer, B.9
  • 37
    • 17744388125 scopus 로고    scopus 로고
    • A meta-analysis of the MTHFR C677T polymorphism and schizophrenia risk
    • Lewis SJ, Zammit S, Gunnell D, Smith GD. 2005. A meta-analysis of the MTHFR C677T polymorphism and schizophrenia risk. Am J Med Genet Part B 135B:2-4.
    • (2005) Am J Med Genet , vol.135 B , Issue.PART B , pp. 2-4
    • Lewis, S.J.1    Zammit, S.2    Gunnell, D.3    Smith, G.D.4
  • 38
    • 0034808335 scopus 로고    scopus 로고
    • A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk
    • Lievers KJ, Boers GH, Verhoef P, den Heijer M, Kluijtmans LA, van der Put NM, Trijbels FJ, Blom HJ. 2001. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med 79:522-528.
    • (2001) J Mol Med , vol.79 , pp. 522-528
    • Lievers, K.J.1    Boers, G.H.2    Verhoef, P.3    den Heijer, M.4    Kluijtmans, L.A.5    van der Put, N.M.6    Trijbels, F.J.7    Blom, H.J.8
  • 40
    • 35048903633 scopus 로고    scopus 로고
    • 5,10- methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease
    • Lin JJ, Yueh KC, Liu CS, Liu JT, Lin SZ. 2007. 5,10- methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease. Acta Neurol Taiwan 16:150-157.
    • (2007) Acta Neurol Taiwan , vol.16 , pp. 150-157
    • Lin, J.J.1    Yueh, K.C.2    Liu, C.S.3    Liu, J.T.4    Lin, S.Z.5
  • 42
    • 20444478969 scopus 로고    scopus 로고
    • Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes
    • Mager A, Koren-Morag N, Shohat M, Harell D, Battler A. 2005. Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes. Am J Cardiol 95:1420-1424.
    • (2005) Am J Cardiol , vol.95 , pp. 1420-1424
    • Mager, A.1    Koren-Morag, N.2    Shohat, M.3    Harell, D.4    Battler, A.5
  • 45
    • 17744400085 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: A Dutch population based case-control study
    • Muntjewerff JW, Hoogendoorn ML, Kahn RS, Sinke RJ, den Heijer M, Kluijtmans LA, Blom HJ. 2005. Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: A Dutch population based case-control study. Am J Med Genet Part B 135B:69-72.
    • (2005) Am J Med Genet , vol.135 B , Issue.PART B , pp. 69-72
    • Muntjewerff, J.W.1    Hoogendoorn, M.L.2    Kahn, R.S.3    Sinke, R.J.4    den Heijer, M.5    Kluijtmans, L.A.6    Blom, H.J.7
  • 46
    • 31544442693 scopus 로고    scopus 로고
    • Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: A meta-analysis
    • Muntjewerff JW, Kahn RS, Blom HJ, den Heijer M. 2006. Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: A meta-analysis. Mol Psychiatry 11:143-149.
    • (2006) Mol Psychiatry , vol.11 , pp. 143-149
    • Muntjewerff, J.W.1    Kahn, R.S.2    Blom, H.J.3    den Heijer, M.4
  • 48
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE. 1998. PedCheck: A program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266.
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 53
    • 0345327788 scopus 로고    scopus 로고
    • Women have later onset than men in schizophrenia-but only in its paranoid form. Results of the DSP project
    • Salokangas RK, Honkonen T, Saarinen S. 2003. Women have later onset than men in schizophrenia-but only in its paranoid form. Results of the DSP project. Eur Psychiatry 18:274-281.
    • (2003) Eur Psychiatry , vol.18 , pp. 274-281
    • Salokangas, R.K.1    Honkonen, T.2    Saarinen, S.3
  • 54
    • 0141448781 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphisms in patients with schizophrenia
    • Sazci A, Ergul E, Guzelhan Y, Kaya G, Kara I. 2003. Methylenetetrahydrofolate reductase gene polymorphisms in patients with schizophrenia. Brain Res Mol Brain Res 117:104-107.
    • (2003) Brain Res Mol Brain Res , vol.117 , pp. 104-107
    • Sazci, A.1    Ergul, E.2    Guzelhan, Y.3    Kaya, G.4    Kara, I.5
  • 55
    • 25644431912 scopus 로고    scopus 로고
    • Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: Association is significant in men but not in women
    • Sazci A, Ergul E, Kucukali I, Kara I, Kaya G. 2005. Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: Association is significant in men but not in women. Prog Neuropsychopharmacol Biol Psychiatry 29:1113-1123.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1113-1123
    • Sazci, A.1    Ergul, E.2    Kucukali, I.3    Kara, I.4    Kaya, G.5
  • 57
    • 50249135384 scopus 로고    scopus 로고
    • Genetic associations with schizophrenia: Meta-analyses of 12 candidate genes
    • Shi J, Gershon ES, Liu C. 2008. Genetic associations with schizophrenia: Meta-analyses of 12 candidate genes. Schizophr Res 104:96-107.
    • (2008) Schizophr Res , vol.104 , pp. 96-107
    • Shi, J.1    Gershon, E.S.2    Liu, C.3
  • 58
    • 11144222668 scopus 로고    scopus 로고
    • Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders
    • Tan EC, Chong SA, Lim LC, Chan AO, Teo YY, Tan CH, Mahendran R. 2004. Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders. Psychiatr Genet 14:227-231.
    • (2004) Psychiatr Genet , vol.14 , pp. 227-231
    • Tan, E.C.1    Chong, S.A.2    Lim, L.C.3    Chan, A.O.4    Teo, Y.Y.5    Tan, C.H.6    Mahendran, R.7
  • 62
    • 0033551550 scopus 로고    scopus 로고
    • Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant: Lack of association with schizophrenia
    • Virgos C, Martorell L, Simo JM, Valero J, Figuera L, Joven J, Labad A, Vilella E. 1999. Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant: Lack of association with schizophrenia. Neuroreport 10:2035-2038.
    • (1999) Neuroreport , vol.10 , pp. 2035-2038
    • Virgos, C.1    Martorell, L.2    Simo, J.M.3    Valero, J.4    Figuera, L.5    Joven, J.6    Labad, A.7    Vilella, E.8
  • 63
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. 1998. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64:169-172.
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 64
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • Wigginton JE, Abecasis GR. 2005. PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 21:3445-3447.
    • (2005) Bioinformatics , vol.21 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 66
    • 33746792898 scopus 로고    scopus 로고
    • C677T and A1298C methylenetetrahydrofolate reductase gene polymorphisms in schizophrenia, bipolar disorder and depression: A meta-analysis of genetic association studies
    • Zintzaras E. 2006. C677T and A1298C methylenetetrahydrofolate reductase gene polymorphisms in schizophrenia, bipolar disorder and depression: A meta-analysis of genetic association studies. Psychiatr Genet 16:105-115.
    • (2006) Psychiatr Genet , vol.16 , pp. 105-115
    • Zintzaras, E.1


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