A linkage disequilibrium study of methylenetetrahydrofolate reductase C677T and schizophrenia

Chinese Journal of Medical Genetics

Volumn 19, Issue 3, 2002, Pages 198-200

  Deng, Hong ^a   Liu, Xiehe ^a   Cai, Guiqing ^a   Sun, Xueli ^a   Wang, Yingcheng ^a   Henry, Terwedow ^a   Wang, Zhaoxi ^a   Xu, Xin ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Linkage disequilibrium; Methylenetetrahydrofolate reductase; Missense mutation; Schizophrenia

Indexed keywords

DIAGNOSIS; DISEASES; ENZYMES; GENES; X RAY DIFFRACTION ANALYSIS;

GENE LINKAGE;

MUTAGENESIS;

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ARTICLE; CONTROLLED STUDY; FAMILY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; SCHIZOPHRENIA; SIBLING;

DNA; FAMILY HEALTH; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MUTATION, MISSENSE; NUCLEAR FAMILY; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; SCHIZOPHRENIA;

EID: 0036281139     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects
2. Human methylenetetrahydrofolate reductases, isolation of cDNA, mapping and mutation identification
3. Gene structure of human and mouse methylenetetrahydrofolate reductase
4. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
5. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
6. Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida
7. Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
8. Inherited disorders of folate transport and metabolism
9. Methylenetetrahydrofolate reductase variant and schizophrenia/depression
10. C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses