Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 - Similarity between human and rat enzymes

Neuroendocrinology Letters

Volumn 30, Issue SUPPL.1, 2009, Pages 52-59

  Mizerovska, Jana ^a   Dracinska, Helena ^a   Arlt, Volker M ^b   Schmeiser, Heinz H ^c   Frei, Eva ^c   Stiborova, Marie ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

3 aminobenzanthrone; 3 nitrobenzanthrone; Cytochrome P450; Metabolism

Indexed keywords

3 AMINOBENZANTHRONE; 3 NITROBENZANTHRONE; ALPHA NAPHTHOFLAVONE; AROMATIC NITRO COMPOUND; CONGRESSANE; CYTOCHROME P450 1A1; CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 INHIBITOR; DIETHYLDITHIOCARBAMIC ACID; FURAFYLLINE; KETOCONAZOLE; N HYDROXY 3 AMINOBENZANTHRONE; SULPHAFENAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME METABOLISM; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME; LIVER MICROSOME METABOLISM; MASS SPECTROMETRY; METABOLITE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLLUTANT; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY;

EID: 77349095696     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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