|
|
Volumn 45, Issue 4, 2010, Pages 1618-1626
|
|
Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Structure-based design, chemistry and activity evaluation. II
a
a
a
a
|
|
Author keywords
Aminopeptidase N; Anti tumor; Cyclic imide; Peptidomimetics
|
|
Indexed keywords
2 [3 (2 AMINO 3 METHYLBUTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2 AMINO 3 METHYLPENTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2 AMINO 3 PHENYLPROPANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2 AMINO 4 METHYLPENTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2 AMINOACETAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2 AMINOPROPANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
2 [3 (2,6 DIAMINOHEXANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ANTIMETASTATIC AGENT;
BENZYL 2 [3 (TERT BUTOXYCARBONYLAMINO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
CARBOXYL GROUP;
CYCLIC AMIDE PEPTIDOMIMETIC;
ESTER DERIVATIVE;
ETHYL 2 [2,6 DIOXO 3 (PYRROLIDINE 2 CARBOXAMIDO)PIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINO 3 METHYLBUTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINO 3 METHYLPENTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINO 3 PHENYLPROPANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINO 4 METHYLPENTANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINOACETAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2 AMINOPROPANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 (2,6 DIAMINOHEXANAMIDO) 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 [2 AMINO 3 (1H IMIDAZOL 4 YL)] 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 [2 AMINO 3 (1H INDOL 3 YL)PROPANAMIDO] 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 [2 AMINO 3 (4 HYDROXYPHENYL)PROPANAMIDO] 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
ETHYL 2 [3 [2 AMINO 4 (METHYLTHIO)BUTANAMIDO] 2,6 DIOXOPIPERIDIN 1 YL]ACETIC ACID;
HYDROXAMIC ACID;
MICROSOMAL AMINOPEPTIDASE;
MOLECULAR SCAFFOLD;
PEPTIDE HYDROLASE INHIBITOR;
PEPTIDOMIMETIC AGENT;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
CYTOSTASIS;
DRUG DESIGN;
DRUG POTENCY;
DRUG PROTEIN BINDING;
ENZYME ACTIVE SITE;
HUMAN;
HUMAN CELL;
IC 50;
LUNG METASTASIS;
METASTASIS INHIBITION;
MOUSE;
NONHUMAN;
ANTIGENS, CD13;
CRYSTALLOGRAPHY, X-RAY;
DRUG DESIGN;
HL-60 CELLS;
HUMANS;
IMIDES;
K562 CELLS;
MAGNETIC RESONANCE SPECTROSCOPY;
MODELS, MOLECULAR;
MOLECULAR MIMICRY;
PEPTIDES, CYCLIC;
PROTEASE INHIBITORS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
STRUCTURE-ACTIVITY RELATIONSHIP;
|
|
EID: 77349091068
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2009.12.071 Document Type: Article |
|
Times cited : (23)
|
|
References (19)
|
