Characterization of a calcitonin gene-related peptide release assay in rat isolated distal colon

Archives of Pharmacal Research

Volumn 32, Issue 12, 2009, Pages 1775-1781

  Kaur, Rejbinder ^a   O'Shaughnessy, Celestine T ^a   Jarvie, Emma M ^a   Winchester, Wendy J ^a   McLean, Peter G ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

ASIC; CGRP; Mast cell; TRPV1

Indexed keywords

BENZALKONIUM CHLORIDE; BRADYKININ; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CAPSAZEPINE; COMPOUND 48-80; KETOTIFEN; PROSTAGLANDIN E2; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ARTICLE; CYTOKINE PRODUCTION; DESCENDING COLON; DRUG RELEASE; ENZYME IMMUNOASSAY; IN VITRO STUDY; MALE; MAST CELL DEGRANULATION; NONHUMAN; PH; RAT;

AMILORIDE; ANIMALS; ANTI-ALLERGIC AGENTS; BENZALKONIUM COMPOUNDS; CALCITONIN GENE-RELATED PEPTIDE; CAPSAICIN; COLON; HYDROGEN-ION CONCENTRATION; INFLAMMATION MEDIATORS; KETOTIFEN; MALE; MAST CELLS; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; P-METHOXY-N-METHYLPHENETHYLAMINE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS; SOLUTIONS; TRPV CATION CHANNELS;

EID: 77249167657     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-2216-8     Document Type: Article

References (42)

1. B. Averbeck P. W. Reeh 2001 Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin Neuropharmacology 40 416 423 10.1016/S0028-3908(00)00171-4 1:CAS:528:DC%2BD3MXpslOntA%3D%3D 11166334 (Pubitemid 32144719)
2. G. Barbara V. Stanghellini R. De Giorgio C. Cremon G. S. Cottrell D. Santini G. Pasquinelli A. M. Morselli-Labate E. F. Grady N. W. Bunnett S. M. Collins R. Corinaldesi 2004 Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome Gastroenterology 126 693 702 10.1053/j.gastro.2003.11.055 14988823 (Pubitemid 38298317)
3. L. Bartho R. Benko R. Patacchini G. Petho U. Holzer-Petsche P. Holzer Z. Lazar S. Undi L. Illenyi A. Antal O. P. Horvath 2004 Effects of capsaicin on visceral smooth muscle: a valuable tool for sensory neurotransmitter identification Eur. J. Pharmacol. 500 143 157 10.1016/j.ejphar.2004.07.020 1:CAS:528:DC%2BD2cXotFClurk%3D 15464028 (Pubitemid 39304004)
4. Beyak, M. J., Bulmer, D. C., Jiang, W., Keating, C., Rong, W., and Grundy, D., Extrinsic sensory afferent nerves innervating the gastrointestinal tract, in Physiology of the Gastrointestinal Tract, Fourth edn, pp. 685-725, (2006).
5. S. Bourdu M. Dapoigny E. Chapuy F. Artigue M. P. Vasson P. Dechelotte G. Bommelaer A. Eschalier D. Ardid 2005 Rectal instillation of butyrate provides a novel clinically relevant model of noninflammatory colonic hypersensitivity in rats Gastroenterology 128 1996 2008 10.1053/j.gastro.2005.03.082 1:CAS:528:DC%2BD2MXlvFKltr4%3D 15940632 (Pubitemid 40824708)
6. S. D. Brain T. J. Williams J. R. Tippins H. R. Morris I. MacIntyre 1985 Calcitonin gene-related peptide is a potent vasodilator Nature 313 54 56 10.1038/313054a0 1:CAS:528:DyaL2MXntlWrtg%3D%3D 3917554 (Pubitemid 15192304)
7. L. Bueno J. Fioramonti 1999 Effects of inflammatory mediators on gut sensitivity Can. J. Gastroenterol. 13 SupplA 42A 46A 10202208
8. M. J. Caterina M. A. Schumacher M. Tominaga T. A. Rosen J. D. Levine D. Julius 1997 The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature 389 816 824 10.1038/39807 1:CAS:528:DyaK2sXmvFSksbs%3D 9349813 (Pubitemid 27462969)
9. A. M. Coelho J. Fioramonti L. Bueno 2000 Systemic lipopolysaccharide influences rectal sensitivity in rats: role of mast cells, cytokines, and vagus nerve Am. J. Physiol. Gastrointest. Liver Physiol. 279 G781 G790 1:CAS:528:DC%2BD3cXnsFOqsr0%3D 11005766
10. S. Dax A. Dubin M. Jetter N. Nasser C. Shah D. Swanson N. I. Carruthers 2002 Vanilloid receptor antagonists: structure-activity relationships via parallel and targeted synthesis Drugs Future 27 SupplA 93
11. C. Eastwood M. Kreis D. Grundy 1996 Activation of intestinal afferents by compound 48/80 in the anaesthetized rat: A possible non-mast cell-mediated effect J. Physiol. 495 99 100
12. E. Ekblad C. Winther R. Ekman R. Hakanson F. Sundler 1987 Projections of peptide-containing neurons in rat small intestine Neuroscience 20 169 188 10.1016/0306-4522(87)90010-8 1:CAS:528:DyaL2sXhsV2qtLw%3D 2436086 (Pubitemid 17015253)
13. N. R. Gavva R. Tamir L. Klionsky M. H. Norman J. C. Louis K. D. Wild J. J. Treanor 2005 Proton activation does not alter antagonist interaction with the capsaicinbinding pocket of TRPV1 Mol. Pharmacol. 68 1524 1533 1:CAS:528:DC%2BD2MXht1yksbnO 16135784
14. P. Geppetti M. Tramontana S. Evangelista D. Renzi C. A. Maggi B. M. Fusco E. Del Bianco 1991 Differential effect on neuropeptide release of different concentrations of hydrogen ions on afferent and intrinsic neurons of the rat stomach Gastroenterology 101 1505 1511 1:CAS:528:DyaK38XpvFyhsw%3D%3D 1720105
15. C. Goso S. Evangelista M. Tramontana S. Manzini P. M. Blumberg A. Szallasi 1993 Topical capsaicin administration protects against trinitrobenzene sulfonic acidinduced colitis in the rat Eur. J Pharmacol. 249 185 190 10.1016/0014-2999(93)90431-G 1:CAS:528:DyaK2cXksFKjuw%3D%3D 8287899 (Pubitemid 23328885)
16. P. Holzer 1998 Implications of tachykinins and calcitonin generelated peptide in inflammatory bowel disease Digestion 59 269 283 10.1159/000007504 1:CAS:528:DyaK1cXltlKitLc%3D 9693197 (Pubitemid 28360681)
17. P. Holzer 2003 Acid-sensitive ion channels in gastrointestinal function Curr. Opin. Pharmacol. 3 618 625 10.1016/j.coph.2003.06.008 1:CAS:528: DC%2BD3sXpt1egsLk%3D 14644014 (Pubitemid 37451870)
18. P. Holzer 2006 Efferent-like roles of afferent neurons in the gut: Blood flow regulation and tissue protection Auton. Neurosci. 125 70 75 10.1016/j.autneu.2006.01.004 16542883
19. R. C. Jones III L. Xu G. F. Gebhart 2005 The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3 J. Neurosci. 25 10981 10989 10.1523/JNEUROSCI.0703-05.2005 1:CAS:528: DC%2BD2MXht1yks7zM 16306411 (Pubitemid 41692628)
20. V. Julia L. Bueno 1997 Tachykininergic mediation of viscerosensitive responses to acute inflammation in rats: Role of CGRP Am. J. Physiol. 272 G141 G146 1:CAS:528:DyaK2sXhtFOjtbc%3D 9038887
21. S. Kilo C. Harding-Rose K. M. Hargreaves C. M. Flores 1997 Peripheral CGRP release as a marker for neurogenic inflammation: a model system for the study of neuropeptide secretion in rat paw skin Pain 73 201 207 10.1016/S0304-3959(97)00108-5 1:CAS:528:DyaK2sXnt1eqsLw%3D 9415506 (Pubitemid 27491681)
22. A. J. Kirkup A. M. Brunsden D. Grundy 2001 Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferents Am. J. Physiol. Gastrointest. Liver Physiol. 280 G787 G794 1:CAS:528:DC%2BD3MXjsVahsLk%3D 11292585
23. M. E. Kreis W. Haupt A. J. Kirkup D. Grundy 1998 Histamine sensitivity of mesenteric afferent nerves in the rat jejunum Am. J. Physiol. 275 G675 G680 1:CAS:528:DyaK1cXmsl2itb8%3D 9756496
24. M. Kress P. W. Reeh L. Vyklicky 1997 An interaction of inflammatory mediators and protons in small diameter dorsal root ganglion neurons of the rat Neurosci. Lett. 224 37 40 10.1016/S0304-3940(97)13450-4 1:CAS:528: DyaK2sXhslOqsr0%3D 9132685 (Pubitemid 27112864)
25. F. D. Manela J. Ren J. Gao J. E. McGuigan R. F. Harty 1995 Calcitonin gene-related peptide modulates acidmediated regulation of somatostatin and gastrin release from rat antrum Gastroenterology 109 701 706 10.1016/0016-5085(95)90376-3 1:CAS:528:DyaK2MXos1Grtbc%3D 7657098
26. U. Martin D. Roemer 1977 Ketotifen: a histamine release inhibitor Monogr. Allergy 12 145 149 1:CAS:528:DyaE1cXlvVeitw%3D%3D 72350
27. A. Opree M. Kress 2000 Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1 beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin J. Neurosci. 20 6289 6293 1:CAS:528:DC%2BD3cXlvVGjtLc%3D 10934280
28. A. J. Page S. M. Brierley C. M. Martin M. P. Price E. Symonds R. Butler J. A. Wemmie L. A. Blackshaw 2005 Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function Gut 54 1408 1415 10.1136/gut.2005.071084 1:CAS:528:DC%2BD2MXhtFCksrfL 15987792 (Pubitemid 41375197)
29. A. B. Penissi M. I. Rudolph M. Villar R. C. Coll T. H. Fogal R. S. Piezzi 2003 Effect of dehydroleucodine on histamine and serotonin release from mast cells in the isolated mouse jejunum Inflamm. Res. 52 199 205 1:CAS:528:DC%2BD3sXkslCntrc%3D 12813624
30. V. Plourde S. St Pierre R. Quirion 1997 Calcitonin generelated peptide in viscerosensitive response to colorectal distension in rats Am. J. Physiol. 273 G191 G196 1:CAS:528:DyaK2sXlt1Srtb4%3D 9252526
31. D. R. Poyner 1992 Calcitonin gene-related peptide: multiple actions, multiple receptors Pharmacol. Ther. 56 23 51 10.1016/0163-7258(92)90036-Y 1:CAS:528:DyaK3sXks1eju7Y%3D 1338400
32. G. W. Read E. F. Kiefer 1979 Benzalkonium chloride: selective inhibitor of histamine release induced by compound 48/80 and other polyamines J. Pharmacol. Exp. Ther. 211 711 715 1:CAS:528:DyaL3cXmvFemtA%3D%3D 92563
33. J. Ren Y. Wang K. Liang J. Gao K. Brewer R. F. Harty 1995 Mechanisms of proton-induced stimulation of CGRP release from rat antrum Regul. Pept. 59 103 109 10.1016/0167-0115(95)00079-Q 1:CAS:528:DyaK2MXotFCqtbo%3D 12506420
34. D. R. Robinson P. A. McNaughton M. L. Evans G. A. Hicks 2004 Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling Neurogastroenterol. Motil. 16 113 124 10.1046/j.1365-2982.2003.00456.x 1:STN:280:DC%2BD2c%2Fmtlyjuw%3D%3D 14764211 (Pubitemid 38253528)
35. W. Rong K. Hillsley J. B. Davis G. Hicks W. J. Winchester D. Grundy 2004 Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice J. Physiol. 560 867 881 10.1113/jphysiol.2004.071746 1:CAS:528:DC%2BD2cXhtVWksr7M 15331673 (Pubitemid 39530124)
36. C. Roza P. W. Reeh P. Substance 2001 calcitonin gene related peptide and PGE2 co-released from the mouse colon: a new model to study nociceptive and inflammatory responses in viscera, in vitro Pain 93 213 219 10.1016/S0304- 3959(01)00318-9 1:CAS:528:DC%2BD3MXmtFWis7g%3D 11514080 (Pubitemid 32763178)
37. X. Su G. F. Gebhart 1998 Mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat are polymodal in character J. Neurophysiol. 80 2632 2644 1:STN:280:DyaK1M%2Fjs12jsQ%3D%3D 9819269 (Pubitemid 28546191)
38. X. Su J. N. Sengupta G. F. Gebhart 1997 Effects of kappa opioid receptor-selective agonists on responses of pelvic nerve afferents to noxious colorectal distension J. Neurophysiol. 78 1003 1012 1:CAS:528:DyaK2sXls1Onsr8%3D 9307130
39. L. Vyklicky H. Knotkova-Urbancova Z. Vitaskova V. Vlachova M. Kress P. W. Reeh 1998 Inflammatory mediators at acidic pH activate capsaicin receptors in cultured sensory neurons from newborn rats J. Neurophysiol. 79 670 676 1:CAS:528:DyaK1cXhsVGrurc%3D 9463430
40. J. Wedemeyer S. J. Galli 2000 Mast cells and basophils in acquired immunity Br. Med. Bull. 56 936 955 10.1258/0007142001903616 1:CAS:528: DC%2BD3MXktVOmtb4%3D 11359630 (Pubitemid 32417161)
41. R. M. Williams H. R. Berthoud R. H. Stead 1997 Vagal afferent nerve fibres contact mast cells in rat small intestinal mucosa Neuroimmunomodulation 4 266 270 1:CAS:528:DyaK1cXjs1Snur0%3D 9650820
42. L. C. Yu M. H. Perdue 2001 Role of mast cells in intestinal mucosal function: studies in models of hypersensitivity and stress Immunol. Rev. 179 61 73 10.1034/j.1600-065X.2001.790107.x 1:CAS:528:DC%2BD3MXhvFeksbk%3D 11292029 (Pubitemid 32171274)