Genetic instability and diminished differentiation capacity in long-term cultured mouse neurosphere cells

Mechanisms of Ageing and Development

Volumn 131, Issue 2, 2010, Pages 124-132

  Vukicevic, Vladimir ^a,c   Jauch, Anna ^b   Dinger, Timo C ^c   Gebauer, Linda ^a   Hornich, Veronika ^c   Bornstein, Stefan R ^a   Ehrhart Bornstein, Monika ^a   Müller, Albrecht M ^c  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Aging; Genetic instability; Neural stem cells; Telomeres

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; GENE PRODUCT; HIGH MOBILITY GROUP A PROTEIN; PROTEIN P19ARF; TELOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; CELL CYCLE PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CHROMOSOMAL INSTABILITY; CHROMOSOME 1; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME REGULATION; FETUS; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC INSTABILITY; GENETIC STABILITY; GENETIC VARIABILITY; MOUSE; NEURAL STEM CELL; NEUROSPHERE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURAL CHROMOSOME ABERRATION; TELOMERE; UPREGULATION;

ANIMALS; BRAIN; CELL CYCLE; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYO, MAMMALIAN; MICE; MICE, INBRED C57BL; MULTIPOTENT STEM CELLS; NERVOUS SYSTEM; NEURONS; SPHEROIDS, CELLULAR; TIME FACTORS;

EID: 77249164976     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2010.01.001     Document Type: Article

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