Characterization and evaluation of avian influenza NS1 mutant virus as a potential live and killed DIVA (differentiating between infected and vaccinated animals) vaccine for chickens

Vaccine

Volumn 28, Issue 12, 2010, Pages 2388-2396

  Brahmakshatriya, Vinayak R ^a   Lupiani, Blanca ^a,b   Reddy, Sanjay M ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Avian influenza; Chickens; DIVA; NS1; Vaccine

Indexed keywords

AVIAN INFLUENZA VACCINE; BETA INTERFERON; LIVE VACCINE; NONSTRUCTURAL PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVIAN INFLUENZA; CHICKEN; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; DRUG SAFETY; DRUG STABILITY; EMBRYO; HUMAN; HUMAN CELL; INFLUENZA VIRUS; INFLUENZA VIRUS A H5N3; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INDUCTION; STRAIN DIFFERENCE; TREATMENT OUTCOME; VIRUS ATTENUATION; VIRUS CHARACTERIZATION; VIRUS MUTANT; VIRUS STRAIN; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; ANTIBODIES, VIRAL; CHICKENS; INFLUENZA A VIRUS; INFLUENZA IN BIRDS; INFLUENZA VACCINES; LUNG; PLAQUE ASSAY; POULTRY DISEASES; SERIAL PASSAGE; SUPPRESSION, GENETIC; VACCINES, ATTENUATED; VACCINES, INACTIVATED; VACCINES, MARKER; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE;

EID: 77249145334     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.12.074     Document Type: Article

References (55)

1. Chen W., Calvo P.A., Malide D., Gibbs J., Schubert U., Bacik I., et al. A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 7 December (12) (2001) 1306-1312
2. Fouchier R.A., Munster V., Wallensten A., Bestebroer T.M., Herfst S., Smith D., et al. Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls. J Virol 79 March (5) (2005) 2814-2822
3. Webster R.G., Bean W.J., Gorman O.T., Chambers T.M., and Kawaoka Y. Evolution and ecology of influenza A viruses. Microbiol Rev 56 March (1) (1992) 152-179
4. Alexander D.J. An overview of the epidemiology of avian influenza. Vaccine 25 July (30) (2007) 5637-5644
5. Alexander D.J. A review of avian influenza in different bird species. Vet Microbiol 74 May (1-2) (2000) 3-13
6. Garcia M., Crawford J.M., Latimer J.W., Rivera-Cruz E., and Perdue M.L. Heterogeneity in the haemagglutinin gene and emergence of the highly pathogenic phenotype among recent H5N2 avian influenza viruses from Mexico. J Gen Virol 77 July (Pt 7) (1996) 1493-1504
7. Rohm C., Horimoto T., Kawaoka Y., Suss J., and Webster R.G. Do hemagglutinin genes of highly pathogenic avian influenza viruses constitute unique phylogenetic lineages?. Virology 209 June (2) (1995) 664-670
8. Swayne D., and Kapczynski D. Avian influenza control strategies. In: Swayne D. (Ed). Avian influenza (2008), Blackwell Publishing, Ames 407-451
9. Asplin F.D. Examination of sera from wildfowl for antibodies against the viruses of duck plague, duck hepatitis and duck influenza. Vet Rec 87 August (7) (1970) 182-183
10. Cheung C.Y., Poon L.L., Lau A.S., Luk W., Lau Y.L., Shortridge K.F., et al. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?. Lancet 360 December (9348) (2002) 1831-1837
11. Easterday B.C., Trainer D.O., Tumova B., and Pereira H.G. Evidence of infection with influenza viruses in migratory waterfowl. Nature 219 August (5153) (1968) 523-524
12. Hatta M., Gao P., Halfmann P., and Kawaoka Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 293 September (5536) (2001) 1840-1842
13. Li Z., Chen H., Jiao P., Deng G., Tian G., Li Y., et al. Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model. J Virol 79 September (18) (2005) 12058-12064
14. Hinshaw V.S., Nettles V.F., Schorr L.F., Wood J.M., and Webster R.G. Influenza virus surveillance in waterfowl in Pennsylvania after the H5N2 avian outbreak. Avian Dis 30 January-March (1) (1986) 207-212
15. Lipkind M., Shoham D., and Shihmanter E. Isolation of influenza viruses from rock partridges in Israel. Vet Rec 109 December (24) (1981) 540
16. Seo S.H., Hoffmann E., and Webster R.G. Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med 8 September (9) (2002) 950-954
17. Perkins L.E., and Swayne D.E. Varied pathogenicity of a Hong Kong-origin H5N1 avian influenza virus in four passerine species and budgerigars. Vet Pathol 40 January (1) (2003) 14-24
18. Perkins L.E., and Swayne D.E. Susceptibility of laughing gulls (Larus atricilla) to H5N1 and H5N3 highly pathogenic avian influenza viruses. Avian Dis 46 October-December (4) (2002) 877-885
19. Shinya K., Hamm S., Hatta M., Ito H., Ito T., and Kawaoka Y. PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice. Virology 320 March (2) (2004) 258-266
20. Garcia-Sastre A. Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses. Virology 279 January (2) (2001) 375-384
21. Wang X., Li M., Zheng H., Muster T., Palese P., Beg A.A., et al. Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol 74 December (24) (2000) 11566-11573
22. Cauthen A.N., Swayne D.E., Sekellick M.J., Marcus P.I., and Suarez D.L. Amelioration of influenza virus pathogenesis in chickens attributed to the enhanced interferon-inducing capacity of a virus with a truncated NS1 gene. J Virol 81 February (4) (2007) 1838-1847
23. Egorov A., Brandt S., Sereinig S., Romanova J., Ferko B., Katinger D., et al. Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells. J Virol 72 August (8) (1998) 6437-6441
24. Garcia-Sastre A., Egorov A., Matassov D., Brandt S., Levy D.E., Durbin J.E., et al. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252 December (2) (1998) 324-330
25. Nemeroff M.E., Qian X.Y., and Krug R.M. The influenza virus NS1 protein forms multimers in vitro and in vivo. Virology 212 October (2) (1995) 422-428
26. Wang X., Basler C.F., Williams B.R., Silverman R.H., Palese P., and Garcia-Sastre A. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. J Virol 76 December (24) (2002) 12951-12962
27. Fernandez-Sesma A., Marukian S., Ebersole B.J., Kaminski D., Park M.S., Yuen T., et al. Influenza virus evades innate and adaptive immunity via the NS1 protein. J Virol 80 July (13) (2006) 6295-6304
28. Ferko B., Stasakova J., Romanova J., Kittel C., Sereinig S., Katinger H., et al. Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes. J Virol 78 December (23) (2004) 13037-13045
29. Solorzano A., Webby R.J., Lager K.M., Janke B.H., Garcia-Sastre A., and Richt J.A. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J Virol 79 June (12) (2005) 7535-7543
30. Wang L., Suarez D.L., Pantin-Jackwood M., Mibayashi M., Garcia-Sastre A., Saif Y.M., et al. Characterization of influenza virus variants with different sizes of the non-structural (NS) genes and their potential as a live influenza vaccine in poultry. Vaccine 26 July (29-30) (2008) 3580-3586
31. Quinlivan M., Zamarin D., Garcia-Sastre A., Cullinane A., Chambers T., and Palese P. Attenuation of equine influenza viruses through truncations of the NS1 protein. J Virol 79 July (13) (2005) 8431-8439
32. Mueller S.N., Langley W.A., Carnero E., Garcia-Sastre A., and Ahmed R. Immunization with live-attenuated influenza viruses expressing altered NS1 proteins results in potent and protective memory CD8+ T cells responses. J Virol November (2009) 10.1128/JVI.01317-09
33. Chambers T.M., Quinlivan M., Sturgill T., Cullinane A., Horohov D.W., Zamarin D., et al. Influenza A viruses with truncated NS1 as modified live virus vaccines: pilot studies of safety and efficacy in horses. Equine Vet J 41 January (1) (2009) 87-92
34. Suarez D.L. Overview of avian influenza DIVA test strategies. Biologicals 33 December (4) (2005) 221-226
35. Zhao S., Jin M., Li H., Tan Y., Wang G., Zhang R., et al. Detection of antibodies to the nonstructural protein (NS1) of avian influenza viruses allows distinction between vaccinated and infected chickens. Avian Dis 49 December (4) (2005) 488-493
36. Birch-Machin I., Rowan A., Pick J., Mumford J., and Binns M. Expression of the nonstructural protein NS1 of equine influenza A virus: detection of anti-NS1 antibody in post infection equine sera. J Virol Methods 65 May (2) (1997) 255-263
37. Richt J.A., Lekcharoensuk P., Lager K.M., Vincent A.L., Loiacono C.M., Janke B.H., et al. Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine. J Virol 80 November (22) (2006) 11009-11018
38. Sekellick M.J., and Marcus P.I. Induction of high titer chicken interferon. Methods Enzymol 119 (1986) 115-125
39. Hoffmann E., Neumann G., Kawaoka Y., Hobom G., and Webster R.G. A DNA transfection system for generation of influenza A virus from eight plasmids. Proc Natl Acad Sci USA 97 May (11) (2000) 6108-6113
40. Hoffmann E., Stech J., Guan Y., Webster R.G., and Perez D.R. Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 146 December (12) (2001) 2275-2289
41. Chin P.S., Hoffmann E., Webby R., Webster R.G., Guan Y., Peiris M., et al. Molecular evolution of H6 influenza viruses from poultry in Southeastern China: prevalence of H6N1 influenza viruses possessing seven A/Hong Kong/156/97 (H5N1)-like genes in poultry. J Virol 76 January (2) (2002) 507-516
42. Reed L.J., and Muench H. A simple method of estimating fifty percent endpoints. Am J Epidemiol 1938 27 May (3) (1938) 493-497
43. Swayne D.E., Senne D.A., and Beard C.W. Isolation and identification of avian pathogens. In: Swayne JRG D.E., Jackwood M.W., Pearson J.E., and Reed W.M. (Eds). Isolation and identification of avian pathogens. 4th ed. (1998), American Association of Avian Pathologists, Kennett Square, PA 150-155
44. Watson D.S., Reddy S.M., Brahmaksatriya V., and Lupiani B. A multiplexed immunoassay for detection of antibodies against avian influenza virus. J Immunol Methods November (2008)
45. Hoffmann E., Mahmood K., Yang C.F., Webster R.G., Greenberg H.B., and Kemble G. Rescue of influenza B virus from eight plasmids. Proc Natl Acad Sci USA 99 August (17) (2002) 11411-11416
46. Stone H.D. Efficacy of avian influenza oil-emulsion vaccines in chickens of various ages. Avian Dis 31 July-September (3) (1987) 483-490
47. Stone H.D., Brugh M., and Beard C.W. Influence of formulation on the efficacy of experimental oil-emulsion Newcastle disease vaccines. Avian Dis 27 July-September (3) (1983) 688-697
48. OIE. Avian Influenza. Chapter 2.3.4. Manual of diagnostic tests and vaccines of terrestrial animals; 2009. Available from: http://www.oie.int/eng/normes/mmanual/A_summry.htm [cited 2009 December].
49. Capua I., Cattoli G., Marangon S., Bortolotti L., and Ortali G. Strategies for the control of avian influenza in Italy. Vet Rec 150 February (7) (2002) 223
50. Cattoli G., Terregino C., Brasola V., Rodriguez J.F., and Capua I. Development and preliminary validation of an ad hoc N1-N3 discriminatory test for the control of avian influenza in Italy. Avian Dis 47 3 Suppl. (2003) 1060-1062
51. Lee C.W., Senne D.A., and Suarez D.L. Generation of reassortant influenza vaccines by reverse genetics that allows utilization of a DIVA (Differentiating Infected from Vaccinated Animals) strategy for the control of avian influenza. Vaccine 22 August (23-24) (2004) 3175-3181
52. Tumpey T.M., Alvarez R., Swayne D.E., and Suarez D.L. Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virus. J Clin Microbiol 43 February (2) (2005) 676-683
53. Sekellick M.J., and Marcus P.I. Interferon induction by viruses. XIV. Development of interferon inducibility and its inhibition in chick embryo cells "aged" in vitro. J Interferon Res 5 Fall (4) (1985) 651-667
54. Sekellick M.J., Biggers W.J., and Marcus P.I. Development of the interferon system. I. In chicken cells development in ovo continues on time in vitro. In Vitro Cell Dev Biol 26 October (10) (1990) 997-1003
55. Watson D.S., Reddy S.M., Brahmakshatriya V., and Lupiani B. A multiplexed immunoassay for detection of antibodies against avian influenza virus. J Immunol Methods 340 January (2) (2009) 123-131