Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins

Protein Expression and Purification

Volumn 71, Issue 1, 2010, Pages 103-107

  Han, Byeong Gu ^a,f   Cho, Jea Won ^a   Cho, Young Doo ^a   Kim, Soo Youl ^a   Yoon, Hye Jin ^b   Song, Hyun Kyu ^c   Cheong, Hae Kap ^d,e   Jeon, Young Ho ^d,e   Lee, Dong ki ^f   Lee, Sangho ^f   Lee, Byung Il ^a  

^a National Cancer Center   (South Korea)

^b Seoul National University   (South Korea)

^c Korea University   (South Korea)

^d Korea Basic Science Institute (KBSI)   (South Korea)

^e University of Science and Technology (UST)   (South Korea)

^f Sungkyunkwan University   (South Korea)

Author keywords

HRASLS3; HREV107; RARRES3; RIG1; TIG3

Indexed keywords

HRASLS3 PROTEIN, HUMAN; PHOSPHOLIPASE A2; RARRES3 PROTEIN, HUMAN; RECOMBINANT PROTEIN; RETINOIC ACID RECEPTOR; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BIOCHEMISTRY; CHEMISTRY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; BIOCHEMISTRY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; TUMOR SUPPRESSOR PROTEINS;

BACTERIA (MICROORGANISMS);

EID: 77249111668     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2010.01.018     Document Type: Article

References (27)

1. DiSepio D., Ghosn C., Eckert R.L., Deucher A., Robinson N., Duvic M., Chandraratna R.A., and Nagpal S. Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene. Proc. Natl. Acad. Sci. USA 95 (1998) 14811-14815
2. Tsai F.M., Shyu R.Y., and Jiang S.Y. RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras. Cell. Signal. 18 (2006) 349-358
3. Deucher A., Nagpal S., Chandraratna R.A., Di Sepio D., Robinson N.A., Dashti S.R., and Eckert R.L. The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity. Int. J. Oncol. 17 (2000) 1195-1203
4. Huang S.L., Shyu R.Y., Yeh M.Y., and Jiang S.Y. The retinoid-inducible gene I: effect on apoptosis and mitogen-activated kinase signal pathways. Anticancer Res. 22 (2002) 799-804
5. Sturniolo M.T., Dashti S.R., Deucher A., Rorke E.A., Broome A.M., Chandraratna R.A., Keepers T., and Eckert R.L. A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase. J. Biol. Chem. 278 (2003) 48066-48073
6. Tsai F.M., Shyu R.Y., Lin S.C., Wu C.C., and Jiang S.Y. Induction of apoptosis by the retinoid inducible growth regulator RIG1 depends on the NC motif in HtTA cervical cancer cells. BMC Cell Biol. 10 (2009) 15
7. Lotz K., Kellner T., Heitmann M., Nazarenko I., Noske A., Malek A., Gontarewicz A., Schafer R., and Sers C. Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen-activated kinase-dependent and -independent mechanisms. Int. J. Cancer 116 (2005) 894-902
8. Jiang S.Y., Chou J.M., Leu F.J., Hsu Y.Y., Shih Y.L., Yu J.C., Lee M.S., and Shyu R.Y. Decreased expression of type II tumor suppressor gene RARRES3 in tissues of hepatocellular carcinoma and cholangiocarcinoma. World J. Gastroenterol. 11 (2005) 948-953
9. Duvic M., Helekar B., Schulz C., Cho M., DiSepio D., Hager C., DiMao D., Hazarika P., Jackson B., Breuer-McHam J., Young J., Clayman G., Lippman S.M., Chandraratna R.A., Robinson N.A., Deucher A., Eckert R.L., and Nagpal S. Expression of a retinoid-inducible tumor suppressor, tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer. Clin. Cancer Res. 6 (2000) 3249-3259
10. Shyu R.Y., Jiang S.Y., Chou J.M., Shih Y.L., Lee M.S., Yu J.C., Chao P.C., Hsu Y.J., and Jao S.W. RARRES3 expression positively correlated to tumour differentiation in tissues of colorectal adenocarcinoma. Br. J. Cancer 89 (2003) 146-151
11. Ou C.C., Hsu S.C., Hsieh Y.H., Tsou W.L., Chuang T.C., Liu J.Y., and Kao M.C. Downregulation of HER2 by RIG1 involves the PI3K/Akt pathway in ovarian cancer cells. Carcinogenesis 29 (2008) 299-306
12. Sers C., Emmenegger U., Husmann K., Bucher K., Andres A.C., and Schafer R. Growth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumors. J. Cell Biol. 136 (1997) 935-944
13. Sers C., Husmann K., Nazarenko I., Reich S., Wiechen K., Zhumabayeva B., Adhikari P., Schroder K., Gontarewicz A., and Schafer R. The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells. Oncogene 21 (2002) 2829-2839
14. Siegrist S., Feral C., Chami M., Solhonne B., Mattei M.G., Rajpert-De Meyts E., Guellaen G., and Bulle F. hH-Rev107, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors. Oncogene 20 (2001) 5155-5163
15. Yanatatsaneejit P., Chalermchai T., Kerekhanjanarong V., Shotelersuk K., Supiyaphun P., Mutirangura A., and Sriuranpong V. Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma. Oral Oncol. 44 (2008) 400-406
16. Nazarenko I., Schafer R., and Sers C. Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells. J. Cell Sci. 120 (2007) 1393-1404
17. Marchler-Bauer A., Panchenko A.R., Shoemaker B.A., Thiessen P.A., Geer L.Y., and Bryant S.H. CDD: a database of conserved domain alignments with links to domain three-dimensional structure. Nucleic Acids Res. 30 (2002) 281-283
18. Anantharaman V., and Aravind L. Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol. 4 (2003) R11
19. Hughes P.J., and Stanway G. The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferation. J. Gen. Virol. 81 (2000) 201-207
20. Duncan R.E., Sarkadi-Nagy E., Jaworski K., Ahmadian M., and Sul H.S. Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). J. Biol. Chem. 283 (2008) 25428-25436
21. Uyama T., Jin X.H., Tsuboi K., Tonai T., and Ueda N. Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. Biochim. Biophys. Acta 1791 (2009) 1114-1124
22. Uyama T., Morishita J., Jin X.H., Okamoto Y., Tsuboi K., and Ueda N. The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. J. Lipid Res. 50 (2009) 685-693
23. Tsai F.M., Shyu R.Y., and Jiang S.Y. RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus. Cell. Signal. 19 (2007) 989-999
24. Apolloni A., Prior I.A., Lindsay M., Parton R.G., and Hancock J.F. H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Mol. Cell Biol. 20 (2000) 2475-2487
25. Goodwin J.S., Drake K.R., Rogers C., Wright L., Lippincott-Schwartz J., Philips M.R., and Kenworthy A.K. Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway. J. Cell Biol. 170 (2005) 261-272
26. Rocks O., Peyker A., Kahms M., Verveer P.J., Koerner C., Lumbierres M., Kuhlmann J., Waldmann H., Wittinghofer A., and Bastiaens P.I. An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 307 (2005) 1746-1752
27. Roy S., Plowman S., Rotblat B., Prior I.A., Muncke C., Grainger S., Parton R.G., Henis Y.I., Kloog Y., and Hancock J.F. Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Mol. Cell Biol. 25 (2005) 6722-6733