메뉴 건너뛰기




Volumn 29, Issue 2, 2008, Pages 299-306

Downregulation of HER2 by RIG1 involves the PI3K/Akt pathway in ovarian cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GAMMA INTERFERON; MAMMALIAN TARGET OF RAPAMYCIN; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P185; PROTEIN SERINE THREONINE KINASE; RETINOID INDUCIBLE GENE 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 40549137759     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm263     Document Type: Article
Times cited : (34)

References (44)
  • 1
    • 0032479056 scopus 로고    scopus 로고
    • IFN-c induction of p21WAF1 in prostate cancer cells: role in cell cycle, alteration of phenotype and invasive potential
    • Hobeika,A.C. et al. (1998) IFN-c induction of p21WAF1 in prostate cancer cells: role in cell cycle, alteration of phenotype and invasive potential. Int. J. Cancer, 77, 138-145.
    • (1998) Int. J. Cancer , vol.77 , pp. 138-145
    • Hobeika, A.C.1
  • 2
    • 0034660857 scopus 로고    scopus 로고
    • Down-regulation of neu/HER-2 by interferon-c in prostate cancer cells
    • Kominsky,S. et al. (2000) Down-regulation of neu/HER-2 by interferon-c in prostate cancer cells. Cancer Res., 60, 3904-3908.
    • (2000) Cancer Res , vol.60 , pp. 3904-3908
    • Kominsky, S.1
  • 3
    • 0032425206 scopus 로고    scopus 로고
    • Identification and characterization of a retinoidinduced class II tumor suppressor/growth regulatory gene
    • DiSepio,D. et al. (1998) Identification and characterization of a retinoidinduced class II tumor suppressor/growth regulatory gene. Proc. Natl Acad. Sci. USA, 95, 14811-14815.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 14811-14815
    • DiSepio, D.1
  • 4
    • 0033984568 scopus 로고    scopus 로고
    • Cloning and characterization of a novel retinoidinducible gene 1(RIG1) deriving from human gastric cancer cells
    • Huang,S.L. et al. (2000) Cloning and characterization of a novel retinoidinducible gene 1(RIG1) deriving from human gastric cancer cells. Mol. Cell Endocrinol., 159, 15-24.
    • (2000) Mol. Cell Endocrinol. , vol.159 , pp. 15-24
    • Huang, S.L.1
  • 5
    • 0037171945 scopus 로고    scopus 로고
    • The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgammainduced cell death in human ovarian carcinoma cells
    • Sers,C. et al. (2002) The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgammainduced cell death in human ovarian carcinoma cells. Oncogene, 21, 2829-2839.
    • (2002) Oncogene , vol.21 , pp. 2829-2839
    • Sers, C.1
  • 6
    • 0033887696 scopus 로고    scopus 로고
    • Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer
    • Duvic,M. et al. (2000) Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer. Clin. Cancer Res., 6, 3249-3259.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3249-3259
    • Duvic, M.1
  • 7
    • 0042345037 scopus 로고    scopus 로고
    • RARRES3 expression positively correlated to tumour differentiation in tissues of colorectal adenocarcinoma
    • Shyu,R.Y. et al. (2003) RARRES3 expression positively correlated to tumour differentiation in tissues of colorectal adenocarcinoma. Br. J. Cancer, 89, 146-151.
    • (2003) Br. J. Cancer , vol.89 , pp. 146-151
    • Shyu, R.Y.1
  • 8
    • 0034548658 scopus 로고    scopus 로고
    • The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity
    • Deucher,A. et al. (2000) The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity. Int. J. Oncol., 17, 1195-1203.
    • (2000) Int. J. Oncol. , vol.17 , pp. 1195-1203
    • Deucher, A.1
  • 9
    • 0036244379 scopus 로고    scopus 로고
    • The retinoid-inducible gene I: effect on apoptosis and mitogen-activated kinase signal pathways
    • Huang,S.L. et al. (2002) The retinoid-inducible gene I: effect on apoptosis and mitogen-activated kinase signal pathways. Anticancer Res., 22, 799-804.
    • (2002) Anticancer Res , vol.22 , pp. 799-804
    • Huang, S.L.1
  • 10
    • 0041589184 scopus 로고    scopus 로고
    • Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype
    • Higuchi,E. et al. (2003) Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype. Oncogene, 22, 4627-4635.
    • (2003) Oncogene , vol.22 , pp. 4627-4635
    • Higuchi, E.1
  • 11
    • 0347481365 scopus 로고    scopus 로고
    • A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase
    • Sturniolo,M.T. et al. (2003) A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase. J. Biol. Chem., 28, 48066-48073.
    • (2003) J. Biol. Chem. , vol.28 , pp. 48066-48073
    • Sturniolo, M.T.1
  • 12
    • 27844440785 scopus 로고    scopus 로고
    • RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras
    • Tsai,F.M. et al. (2006) RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras. Cell Signal., 18, 349-358.
    • (2006) Cell Signal , vol.18 , pp. 349-358
    • Tsai, F.M.1
  • 13
    • 0019474922 scopus 로고
    • Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts
    • Shih,C. et al. (1981) Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature, 290, 261-264.
    • (1981) Nature , vol.290 , pp. 261-264
    • Shih, C.1
  • 14
    • 0022399581 scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens,L. et al. (1985) Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science, 230, 1132-1139.
    • (1985) Science , vol.230 , pp. 1132-1139
    • Coussens, L.1
  • 15
    • 0022406444 scopus 로고
    • Amplification of a novel v-erbB-related gene in a human mammary carcinoma
    • King,C.R. et al. (1985) Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science, 229, 974-976.
    • (1985) Science , vol.229 , pp. 974-976
    • King, C.R.1
  • 16
    • 0024411031 scopus 로고
    • Heterogeneous expression of erbB-2 messenger RNA in human breast cancer
    • King,C.R. et al. (1989) Heterogeneous expression of erbB-2 messenger RNA in human breast cancer. Cancer Res., 49, 4185-4191.
    • (1989) Cancer Res , vol.49 , pp. 4185-4191
    • King, C.R.1
  • 17
    • 0022588467 scopus 로고
    • Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
    • Yamamoto,T. et al. (1986) Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature, 319, 230-234
    • (1986) Nature , vol.319 , pp. 230-234
    • Yamamoto, T.1
  • 18
    • 0026512772 scopus 로고
    • Aberrant expression of the c-erbB-2/neu protooncogene in ovarian cancer
    • Hung,M.C. et al. (1992) Aberrant expression of the c-erbB-2/neu protooncogene in ovarian cancer. Cancer Lett., 61, 95-103.
    • (1992) Cancer Lett , vol.61 , pp. 95-103
    • Hung, M.C.1
  • 19
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon,D.J. et al. (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science, 235, 177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1
  • 20
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • Yarden,Y. et al. (2001) Untangling the ErbB signalling network. Nat. Rev. Mol. Cell Biol., 2, 127-137
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 127-137
    • Yarden, Y.1
  • 21
    • 0034222135 scopus 로고    scopus 로고
    • Role of erbB2 in breast cancer chemosensitivity
    • Yu,D. et al. (2000) Role of erbB2 in breast cancer chemosensitivity. Bio-Essays, 22, 673-680.
    • (2000) Bio-Essays , vol.22 , pp. 673-680
    • Yu, D.1
  • 22
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: the complexity of targeted inhibitors
    • Hynes,N.E. et al. (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat. Rev. Cancer, 5, 341-354
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1
  • 23
    • 0032576871 scopus 로고    scopus 로고
    • The N-terminal 178-amino-acid domain only of the SV40 large T antigen acts as a transforming suppressor of the HER-2/neu oncogene
    • Kao,M.C. et al. (1998) The N-terminal 178-amino-acid domain only of the SV40 large T antigen acts as a transforming suppressor of the HER-2/neu oncogene. Oncogene, 16, 547-554.
    • (1998) Oncogene , vol.16 , pp. 547-554
    • Kao, M.C.1
  • 24
    • 0037196346 scopus 로고    scopus 로고
    • The N-terminal domain of SV40 large T antigen represses the HER2-mediated transformation and metastatic potential in breast cancers
    • Chuang,T.C. et al. (2002) The N-terminal domain of SV40 large T antigen represses the HER2-mediated transformation and metastatic potential in breast cancers. FEBS Lett., 511, 46-50.
    • (2002) FEBS Lett , vol.511 , pp. 46-50
    • Chuang, T.C.1
  • 25
    • 3242685815 scopus 로고    scopus 로고
    • Inhibition of fatty acid synthase (FAS) suppresses HER2 (erbB-2) oncogene overexpression in cancer cells
    • Menendez,J.A. et al. (2004) Inhibition of fatty acid synthase (FAS) suppresses HER2 (erbB-2) oncogene overexpression in cancer cells. Proc. Natl Acad. Sci. USA, 101, 10715-10720.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 10715-10720
    • Menendez, J.A.1
  • 26
    • 33644529055 scopus 로고    scopus 로고
    • ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells
    • Klos,K.S. et al. (2006) ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells. Cancer Res., 15, 2028-2037.
    • (2006) Cancer Res , vol.15 , pp. 2028-2037
    • Klos, K.S.1
  • 27
    • 17444448391 scopus 로고    scopus 로고
    • The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis
    • Xing,X. et al. (2000) The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis. Nat. Med., 6, 189-195.
    • (2000) Nat. Med. , vol.6 , pp. 189-195
    • Xing, X.1
  • 28
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara,N. et al. (1997) The biology of vascular endothelial growth factor. Endocr. Rev., 18, 4-25.
    • (1997) Endocr. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1
  • 29
    • 33745828702 scopus 로고    scopus 로고
    • EGF-ERBB signalling: towards the systems level
    • Citri,A. et al. (2006) EGF-ERBB signalling: towards the systems level. Nat. Rev. Mol. Cell Biol., 7, 505-516.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 505-516
    • Citri, A.1
  • 30
    • 0026718293 scopus 로고
    • Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine
    • Krzyzosiak,W.J. et al. (1992) Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine. Proc. Natl Acad. Sci. USA, 89, 4879-4883.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4879-4883
    • Krzyzosiak, W.J.1
  • 31
    • 0037163072 scopus 로고    scopus 로고
    • Silencing of the mouse H-rev107 gene encoding a class II tumor suppressor by CpG methylation
    • Roder,K. et al. (2002) Silencing of the mouse H-rev107 gene encoding a class II tumor suppressor by CpG methylation. J. Biol. Chem., 277, 30543-30550.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30543-30550
    • Roder, K.1
  • 32
    • 18044368283 scopus 로고    scopus 로고
    • Identification and characterization of the retinoic acid response elements in the human RIG1 gene promoter
    • Jiang,S.Y. et al. (2005) Identification and characterization of the retinoic acid response elements in the human RIG1 gene promoter. Biochem. Biophys. Res. Commun., 331, 630-639.
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 630-639
    • Jiang, S.Y.1
  • 33
    • 23944522261 scopus 로고    scopus 로고
    • Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen-activated kinase-dependent and -independent mechanisms
    • Lotz,K. et al. (2005) Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen-activated kinase-dependent and -independent mechanisms. Int. J. Cancer, 116, 894-902.
    • (2005) Int. J. Cancer , vol.116 , pp. 894-902
    • Lotz, K.1
  • 34
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: positive and negative feedback loops
    • Harris,S.L. et al. (2005) The p53 pathway: positive and negative feedback loops. Oncogene, 24, 2899-2908.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1
  • 35
    • 85047699328 scopus 로고    scopus 로고
    • Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis
    • Gottlieb,T.M. et al. (2002) Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis. Oncogene, 21, 1299-1303.
    • (2002) Oncogene , vol.21 , pp. 1299-1303
    • Gottlieb, T.M.1
  • 36
    • 19944374798 scopus 로고    scopus 로고
    • Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
    • Wang,H.Q. et al. (2005) Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells. Oncogene, 24, 3574-3582.
    • (2005) Oncogene , vol.24 , pp. 3574-3582
    • Wang, H.Q.1
  • 37
    • 22244453690 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
    • Longva,K.E. et al. (2005) Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int. J. Cancer, 116, 359-367.
    • (2005) Int. J. Cancer , vol.116 , pp. 359-367
    • Longva, K.E.1
  • 38
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman,J. (2002) Role of angiogenesis in tumor growth and metastasis. Semin. Oncol., 29, 15-18.
    • (2002) Semin. Oncol. , vol.29 , pp. 15-18
    • Folkman, J.1
  • 39
    • 0031032073 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma
    • Gasparini,G. et al. (1997) Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J. Natl Cancer Inst., 89, 139-147.
    • (1997) J. Natl Cancer Inst. , vol.89 , pp. 139-147
    • Gasparini, G.1
  • 42
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay,N. et al. (2004) Upstream and downstream of mTOR. Genes Dev., 18, 1926-1945.
    • (2004) Genes Dev , vol.18 , pp. 1926-1945
    • Hay, N.1
  • 43
    • 0346422440 scopus 로고    scopus 로고
    • FKBP12-rapamycin-associated protein or mammalian target of rapamycin (FRAP/mTOR) localization in the endoplasmic reticulum and the Golgi apparatus
    • Drenan,R.M. et al. (2004) FKBP12-rapamycin-associated protein or mammalian target of rapamycin (FRAP/mTOR) localization in the endoplasmic reticulum and the Golgi apparatus. J. Biol. Chem., 279, 772-778.
    • (2004) J. Biol. Chem. , vol.279 , pp. 772-778
    • Drenan, R.M.1
  • 44
    • 33947145667 scopus 로고    scopus 로고
    • Endoplasmic reticulum and Golgi localization sequences for mammalian target of rapamycin
    • Liu,X. et al. (2007) Endoplasmic reticulum and Golgi localization sequences for mammalian target of rapamycin. Mol. Biol. Cell, 18, 1073-1082.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1073-1082
    • Liu, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.