A functional granulocyte colony-stimulating factor receptor is required for normal chemoattractant-induced neutrophil activation

Journal of Clinical Investigation

Volumn 103, Issue 6, 1999, Pages 825-832

  Betsuyaku, Tomoko ^a   Liu, Fulu ^a   Senior, Robert M ^a   Haug, Jeffery S ^a   Brown, Eric J ^a   Jones, Samuel L ^b   Matsushima, Kouji ^c   Link, Daniel C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; COLONY STIMULATING FACTOR RECEPTOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GRANULOCYTE COLONY STIMULATING FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 2;

ARTICLE; CONTROLLED STUDY; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL;

EID: 0033560116     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI5191     Document Type: Article

References (56)

1. Matsushima, K., and Oppenheim, J.J. 1989. Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL-1 and TNF. Cytokine, 1:2-13.
2. Hoch, R.C., Schraufstätter, I.U., and Cochrane, C.G. 1996. In vivo, in vitro, and molecular aspects of interleukin-8 and the interleukin-8 receptors. J. Lab. Clin. Med. 128:134-145.
3. Matsukawa, A., et al. 1995. Neutrophil accumulation and activation by homologous II-8 in rabbits. J. Immunol. 154:5-418-5425.
4. Lloyd, A.R., et al. 1995. Granulocyte-colony stimulating factor and lipopolysaccharide regulate the expression of interleukin 8 receptors on polymorphonuclear leukocytes. J. Biol. Chem. 270:28188-28192.
5. Anderlini, P. Przepiorka, D., Champlin, R., and Korbling, M. 1996. Biologic and clinical effects of granulocyte colony-stimulating factor in normal individuals. Blood. 88:2819-2825.
6. Hakansson, L., et al. 1997. Effects of in vivo administration of G-CSF on neutrophil and eosinophil adhesion. Br. J. Haematol. 98:603-611.
7. Yong, K.L., and Linch, D.C. 1992. Differential effects of granulocyte- and granulocyte-macrophage colony-stimulating factors (G- and GM-CSF) on neutrophil adhesion in vitro and in vivo. Eur. J. Haematol. 49:251-259.
8. Yuo, A., et al. 1989. Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor-mediated agonists and stimulation or C3bi receptor expression and adherence. Blood. 74:2144-2149.
9. Kerst, J.M., et al. 1993. Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells. Blood. 82:3265-3272.
10. Kerst, J.M., et al. 1993. Granulocyte colony-stimulating factor induces hFc gamma RI (CD64 antigen)-positive neutrophils via an effect on myeloid precursor cells. Blood. 81:1457-1464.
11. Gericke, G.H., et al. 1995. Mature polymorphonuclear leukocytes express high-affinity receptors for IgG (Fc gamma RI) after stimulation with granulocyte colony-stimulating factor (G-CSF). J. Leukocyte Biol. 57:455-461.
12. Xu, S., Hoglund, M., and Venge, P. 1996. The effect of granulocyte colony-stimulating factor (G-CSF) on the degranulation of secondary granule proteins from human neutrophils in vivo may be indirect. Br. J. Haematol. 93:558-568.
13. de Haas, M., et al. 1994. Granulocyte colony-stimulating factor administration to healthy volunteers: analysis of the immediate activating effects on circulating neutrophils. Blood. 84:3885-3894.
14. Hoglund, M., Hakansson, L., and Venge, P. 1997. Effects of in vivo administration of G-CSF on neutrophil functions in healthy volunteers. Eur. J. Haematol. 58:195-202.
15. Smith, W.B., Gamble, J.R, and Vadas, M.A. 1994. The role of granulocyte-macrophage and granulocyte colony-stimulating factors in neutrophil transendothelial migration: comparison with interleukin-8. Exp. Hematol. 22:329-334.
16. Yong, K.L. 1996. Granulocyte colony-stimulating factor (G-CSF) increases neutrophil migration across vascular endothelium independent of an effect on adhesion: comparison with granulocyte-macrophage colony-stimulating factor (GM-CSF). Br. J. Haematol. 94:40-47.
17. Yuo, A., Kitagawa, S., Ohsaka, A., Saito, M., and Takaku, F. 1990. Stimulation and priming of human neutrophils by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: qualitative and quantitative differences. Biochem. Biophys. Res. Commun. 171:491-497.
18. Khwaja, A., Carver, J.E., and Linch, D.C. 1992. Interactions of granulocyte-macrophage colony-stimulating factor (CSF), granulocyte CSF, and tumor necrosis factor alpha in the priming of the neutrophil respiratory burst. Blood. 79:745-753.
19. Metcalf, D., Robb, L., Dunn, A.R., Mifsud, S., and Di Rago, L. 1996. Role of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in the development of an acute neutrophil inflammatory response in mice. Blood. 88:3755-3764.
20. Cebon, J., Layton, J.E., Maher, D., and Morsryn, G. 1994. Endogenous haemopoietic growth factors in neutropenia and infection. Br. J. Haematol. 86:265-274.
21. Lieschke, G.J., et al. 1994. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage. progenitor cell deficiency, and impaired neutrophil mobilization. Blood. 84:1737-1746.
22. Liu, F., Wu, H.Y., Wesselschmidt, R., Kornaga, T., and Link, D. 1996. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor deficient mice. Immunity. 5:491-501.
23. Liu, F., Poursine-Laurent, J., Wu, H., and Link, D. 1997. IL-6 and the G-CSF receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation. Blood. 90:2583-2590.
24. Liu, F., Poursine-Laurent, J., and Link, D.C. 1997. The granulocyte colony-stimulating factor receptor is required for rhe mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 bur nor Flt-3 ligand. Blood. 90:2522-2528.
25. Sugawara, T., Miyamoto, M., Takayama, S., and Kato, M. 1995. Separation of neutrophils from blood in human and laboratory animals and comparison of the chemotaxis. J. Pharmacol. Toxicol. Methods. 33:91-100.
26. Wang, J., et al. 1996. Detection of mouse IL-8 receptor homologue expression on peripheral blood leukocytes and mature myeloid lineage cells in bone marrow. J. Leukoc. Biol. 60:372-381.
27. Rosen, H., and Gordon, S. 1987. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J. Exp. Med. 166:1685-701.
28. Lindberg, F.P., et al. 1994. Rh-related antigen CD47 is the signal-transducer integrin-associated protein J. Biol. Chem. 269:1567-1570.
29. cfgr results in defective adhesion-dependent neutrophil functions. J. Cell Biol. 133:895-910.
30. Rot, A. 1991. Chemotactic potency of recombinant human neutrophil attarctant/activation protein-1 (interleukin-8) for polymorphonuclear leukocytes of different species. Cytokine. 3:21-27.
31. Brenner, C.A., Adler, R.R., Rappollee, D.A., Pederson, R.A. and Werb, Z. 1989. Genes for extracellular matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development. Genes Dev. 3:848-859.
32. Mayo, L.A., and Curnutte, J.T. 1990. Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells. Methods Enzymol. 186:567-575.
33. 2 activity in polymorphonuclear neutrophils. J. Biol. Chem. 273:10556-10566.
34. Kim, C.H., and Broxmeyer, H.E. 1998. In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood. 91:100-110.
35. Liu, Z., et al. 1998. Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid. J. Exp. Med. 188:475-482.
36. Cacalano, G., et al. 1994. Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog [published erratum appears in Science, 1995, 270:365]. Science. 265:682-684.
37. Bozic, C.R., et al. 1994. The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization. J. Biol. Chem. 269:29355-29358.
38. Lee, J., et al. 1995. Chemokine binding and activities mediated by the mouse IL-8 receptor. J. Immunol. 155:2158-2164.
39. Borregaard, N., and Cowland, J.B. 1997. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood. 89:3503-3521.
40. Jones, D.H., et al. 1990. Subcellular distribution and mobilization of MAC-1 (CD11b/CD18) in neonatal neutrophils. Blood. 75:488-498.
41. Larsen, C.G., Anderson, A.O., Oppenheim, J.J., and Matsushima, K. 1989. Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 to tumor necrosis factor. Immunology. 68:31-36.
42. Jacob, J., Haug, J.S., Raptis, S., and Link, D.C. 1998. Specific signals generated by the cytoplasmic domain of the G-CSF receptor are not required for G-CSF-dependent granulocytic differentiation. Blood. 92:353-361.
43. Huffman, J.A., Hull, W.M., Dranoff, G., Mulligan, R.C., and Whitsett, J.A. 1996. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J. Clin. Invest. 97:649-655.
44. Dranoff, G., et al. 1994. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science. 264:713-716.
45. Nishinakamura, R., et al. 1996. The pulmonary alveolar proteinosis in granulocyte macrophage colony-stimulating factor/interleukins 3/5 Bc receptor-deficient mice is reversed by bone marrow transplantation. J. Exp. Med. 183:26.57-2662.
46. Sham, R.L., Phatak, P.D., Ihne, T.P., Abboud, C.N., and Packman, C.H. 1993. Signal pathway regulation of interleukin-8-induced actin polymerization in neutrophils. Blood. 82:2546-2551.
47. Brown, E.J. 1997. Adhesive interactions in the immune system. Trends Cell Biol. 7:289-295.
48. Dana, N., Todd, R.F., 3d., Pitt, J., Springer, T.A., and Arnaout, M.A. 1984. Deficiency of a surface membrane glycoprotein (Mol) in man. J. Clin. Invest. 73:153-159.
49. Anderson, D.C., et al. 1985. The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: their quantitative definition and relation to leukocyte dysfunction and clinical features. J. Infect. Dis. 152:668-689.
50. Anderson, D.C., and Springer, T.A. 1987. Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150, 95 glycoproteins. Am. Rev. Med. 38:175-194.
51. Kolanus, W., and Seed, B. 1997. Integrins and inside-out signal transduction: converging signals from PKC and PIP3. Curr. Opin. Cell Biol. 9:725-731.
52. Faull, R.J., and Ginsberg, M.H. 1996. Inside-out signaling through integrins. J. Am. Soc. Nephrol. 7:1091-1097.
53. Stasia, M.J., Jouan, A., Bourmeyster, N., Boquet, P., and Vignais, P.V. 1991. ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility. Biochem. Biophys. Res. Commun. 180:615-622.
54. Laudanna, C., Campbell, J.J., and Butcher, E.C. 1996. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science. 271:981-983.
55. Bashey, A., Healy, L., and Marshall, C.J. 1994. Proliferative but not nonproliferative responses to granulocyte colony-stimulating factor are associated with rapid activation of the p21ras/MAP kinase signalling pathway. Blood. 83:949-957.
56. Mizgerd, J.P., et al. 1997. Neutrophil emigration in the skin, lungs and peritoneum: different requirement for CD11/CD18 revealed by CD18-deficient mice. J. Exp. Med. 186:1357-1364.