Structural analysis of trypanosomal sirtuin: An insight for selective drug design

Molecular Diversity

Volumn 14, Issue 1, 2010, Pages 169-178

  Kaur, Simranjeet ^a   Shivange, Amol V ^a   Roy, Nilanjan ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Cavity depth; Homology modeling; Molecular electrostatic potential; Sir2; Sirtuin; Surface analysis

Indexed keywords

2 HYDROXY 1 NAPHTHALDEHYDE; 4 SIRTINOL; ALDEHYDE DERIVATIVE; CAMBINOL; COUMARIN DERIVATIVE; DIHYDROCOUMARIN; N [3 (4 HYDROXYPHENYL)PROPENOYL]ALANINE TRYPTAMIDE; NICOTINAMIDE; PROTEIN INHIBITOR; SIRTUIN 1; SIRTUIN 2; SPLITOMYCIN; TRYPTAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; MOLECULAR DOCKING; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; COMPUTER SIMULATION; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SIRTUIN 1; SIRTUIN 2; SPECIES SPECIFICITY; STATIC ELECTRICITY; TRYPANOSOMATINA;

EID: 77149176653     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-009-9147-7     Document Type: Article

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