A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei

EMBO Journal

Volumn 22, Issue 21, 2003, Pages 5851-5862

  García Salcedo, José A ^c   Gijón, Purificación ^a   Nolan, Derek P ^b   Tebabi, Patricia ^a   Pays, Etienne ^a  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c NONE

Author keywords

DNA damage; Histone deacetylase; Histone ribosyltransferase; SIR2 homologue; Trypanosoma

Indexed keywords

ALKYLATING AGENT; HISTONE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; PROTEIN TBSIR2RP1; SILENT INFORMATION REGULATOR PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHROMATIN; CHROMOSOME ANALYSIS; CHROMOSOME SEGREGATION; DEACETYLATION; DNA ALKYLATION; DNA RECOMBINATION; DNA REPAIR; ENZYME ACTIVITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTOZOON; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI;

ALKYLATING AGENTS; ANIMALS; DNA DAMAGE; DNA REPAIR; GENES, PROTOZOAN; HISTONE DEACETYLASES; HISTONES; NUCLEAR PROTEINS; PROTOZOAN PROTEINS; SIRTUINS; SUBSTRATE SPECIFICITY; TRYPANOSOMA BRUCEI BRUCEI;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0242556798     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg553     Document Type: Article

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