Oxygen-induced expression of Δ6-, Δ9- and Δ12-desaturase genes modulates fatty acid composition in Mucor rouxii

Applied Microbiology and Biotechnology

Volumn 86, Issue 1, 2010, Pages 327-334

  Ruenwai, Rawisara ^a   Cheevadhanarak, Supapon ^a   Rachdawong, Sansanalak ^a   Tanticharoen, Morakot ^a   Laoteng, Kobkul ^a  

^a KING MONGKUT'S UNIVERSITY OF TECHNOLOGY THONBURI   (Thailand)

Author keywords

Desaturase; Gamma linolenic acid; Gene expression; Mucor rouxii; Oxygen

Indexed keywords

AEROBIC CONDITION; DESATURASE; EFFECT OF OXYGEN; FATTY ACID BIOSYNTHESIS; FATTY ACID COMPOSITION; GAMMA-LINOLENIC ACID; GASEOUS ENVIRONMENTS; LINOLENIC ACIDS; MOLECULAR MECHANISM; MRNA LEVEL; MUCOR ROUXII; OXYGEN EXPOSURE; SATURATED FATTY ACID; TRANSCRIPTIONAL RESPONSE; UNSATURATED FATTY ACIDS;

ACIDS; BIOACTIVITY; BIOCHEMISTRY; FATTY ACIDS; MOLECULAR OXYGEN;

GENE EXPRESSION;

FATTY ACID; GAMMA LINOLENIC ACID; MESSENGER RNA; OXYGEN; UNSATURATED FATTY ACID;

ENZYME; FATTY ACID; FUNGUS; GENE; GENE EXPRESSION; OXIC CONDITIONS; PHYTOMASS; RNA;

ARTICLE; BIOMASS; CONTROLLED STUDY; FAT CONTENT; FATTY ACID ANALYSIS; FATTY ACID SYNTHESIS; FUNGUS CULTURE; GENE EXPRESSION; GENETIC TRANSCRIPTION; LIPID COMPOSITION; LIPOGENESIS; MUCOR; MUCOR ROUXII; NONHUMAN; TRANSCRIPTION REGULATION;

AEROBIOSIS; BIOTECHNOLOGY; CULTURE MEDIA; FATTY ACID DESATURASES; FATTY ACIDS; GAMMA-LINOLENIC ACID; GENE EXPRESSION REGULATION, FUNGAL; MUCOR; OXYGEN;

AMYLOMYCES ROUXII; FUNGI;

EID: 77149175648     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2338-4     Document Type: Article

References (46)

1. 2 and impeller tip speeds Appl Biochem Biotechnol 151 599 609 10.1007/s12010-008-8261-9 1:CAS:528:DC%2BD1cXhsVSitb3M
2. J Bailey-Serres R Chang 2005 Sensing and signalling in response to oxygen deprivation in plants and other organisms Ann Bot 96 507 518 10.1093/aob/mci206 1:CAS:528:DC%2BD2MXhtFGitLnJ (Pubitemid 41298044)
3. CR Barrera 1983 Formation and ultrastructure of Mucor rouxii arthrospores J Bacteriol 155 886 895 1:STN:280:DyaL3s3msFKitg%3D%3D
4. S Bartnicki-Garcia WJ Nickerson 1962 Induction of yeastlike development in Mucor by carbon dioxide J Bacteriol 84 829 840 1:CAS:528:DyaF38XkslyhtLc%3D
5. S Bartnicki-Garcia WJ Nickerson 1962 Nutrition, growth, and morphogenesis of Mucor rouxii J Bacteriol 84 841 858 1:CAS:528:DyaF38Xkslyhtb4%3D
6. KE Bloch 1979 Speculations on the evolution of sterol structure and function Crit Rev Biochem Mol Biol 7 1 5 10.3109/10409237909102566 1:CAS:528:DyaL3cXovFertw%3D%3D
7. 9- unsaturated fatty acids J Biol Chem 235 337 345 1:CAS:528:DyaF3cXmvVyrsg%3D%3D
8. HF Bunn RO Poyton 1996 Oxygen sensing and molecular adaptation to hypoxia Physiol Rev 76 839 885 1:CAS:528:DyaK28XltVags70%3D
9. M Certik L Balteszova J Sajbidor 1997 Lipid formation and γ-linolenic acid production by Mucorales fungi grown on sunflower oil Lett Appl Microbiol 25 101 105 10.1046/j.1472-765X.1997.00173.x 1:CAS:528: DyaK2sXlsV2nt74%3D
10. Chaplin MF (1986) Monosaccharide. In: Chaplin MF, Kennedy JF (eds) Carbohydrate Analysis: A practical approach. IRL Press, Oxford, pp 1-13
11. M De Angelis M Gobbetti 2004 Environmental stress responses in Lactobacillus: a review Proteomics 4 106 122 10.1002/pmic.200300497 (Pubitemid 38140879)
12. SD Dyal SS Narine 2005 Implications for the use of Mortierella fungi in the industrial production of essential fatty acids Food Res Int 38 445 467 10.1016/j.foodres.2004.11.002 1:CAS:528:DC%2BD2MXitFeqs7s%3D (Pubitemid 40335621)
13. SD Dyal L Bouzidi SS Narine 2005 Maximizing the production of γ-linolenic acid in Mortierella ramanniana var. ramanniana as a function of pH, temperature and carbon source, nitrogen source, metal ions and oil supplementation Food Res Int 38 815 829 10.1016/j.foodres.2005.04.002 1:CAS:528:DC%2BD2MXlsVClsLo%3D (Pubitemid 40831753)
14. GW Elmer WJ Nickerson 1970 Filamentous growth of Mucor rouxii under nitrogen J Bacteriol 101 592 594 1:CAS:528:DyaE3cXnsF2jug%3D%3D
15. GW Elmer WJ Nickerson 1970 Nutritional requirements for growth and yeastlike development of Mucor rouxii under carbon dioxide J Bacteriol 101 595 602 1:CAS:528:DyaE3cXnsF2juw%3D%3D
16. NJ Færgeman J Knudsen 1997 Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling Biochem J 323 1 12
17. S Fakas M Certik S Papanikolaou G Aggelis M Komaitis M Galiotou-Panayotou 2008 γ-linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources Bioresour Technol 99 5986 5990 10.1016/j.biortech.2007.10.016 1:CAS:528:DC%2BD1cXlvVKrt7g%3D (Pubitemid 351625838)
18. YY Fan RS Chapkin 1998 Importance of dietary γ-linolenic acid in human health and nutrition J Nutr 128 1411 1414 1:CAS:528:DyaK1cXlvVSku7g%3D
19. H Gema A Kavadia D Dimou V Tsagou M Komaitis G Aggelis 2002 Production of γ-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel Appl Microbiol Biotechnol 58 303 307 10.1007/s00253-001-0910-7 1:CAS:528:DC%2BD38XisFOgsbo%3D (Pubitemid 34185573)
20. L Hansson M Dostálek 1988 Effect of culture conditions on mycelial growth and production of γ-linolenic acid by the fungus Mortierella ramanniana Appl Microbiol Biotechnol 28 240 246 10.1007/BF00250448 1:CAS:528:DyaL1cXktlGjtrs%3D
21. L Hansson M Dostálek B Sörenby 1989 Production of γ-linolenic acid by the fungus Mucor rouxii in fed-batch and continuous culture Appl Microbiol Biotechnol 31 223 227 10.1007/BF00258399 1:CAS:528:DyaL1MXltlantbc%3D
22. K Higashiyama K Murakami H Tsujimura N Matsumoto S Fujikawa 1999 Effects of dissolved oxygen on the morphology of an arachidonic acid production by Mortierella alpina 1 S-4 Biotechnol Bioeng 63 442 448 10.1002/(SICI)1097- 0290(19990520)63:4<442::AID-BIT7>3.0.CO;2-9 1:CAS:528:DyaK1MXit12isbY%3D (Pubitemid 29157047)
23. DF Horrobin 1992 Nutritional and medical importance of gamma-linolenic acid Prog Lipid Res 31 163 194 10.1016/0163-7827(92)90008-7 1:CAS:528: DyaK38XlvFSksrs%3D
24. ET Ito RL Cihlar CB Inderlied 1982 Lipid synthesis during morphogenesis of Mucor racemosus J Bacteriol 152 880 887 1:CAS:528:DyaL38XmtFant7c%3D
25. H-D Jang Y-Y Lin S-S Yang 2005 Effect of culture media and conditions on polyunsaturated fatty acids production by Mortierella alpina Bioresour Technol 96 1633 1644 10.1016/j.biortech.2004.12.027 1:CAS:528:DC%2BD2MXmtFCkurc%3D (Pubitemid 40980250)
26. S Jeennor K Laoteng M Tanticharoen S Cheevadhanarak 2006 Comparative fatty acid profiling of Mucor rouxii under different stress conditions FEMS Microbiol Lett 259 60 66 10.1111/j.1574-6968.2006.00242.x 1:CAS:528: DC%2BD28Xlt1Cjt74%3D (Pubitemid 43748662)
27. S Jeennor K Laoteng M Tanticharoen S Cheevadhanarak 2008 Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii Lett Appl Microbiol 46 421 427 10.1111/j.1472-765X.2007.02315.x 1:CAS:528:DC%2BD1cXmtFKmtLw%3D
28. A Kavadia M Komaitis I Chevalot F Blanchard I Marc G Aggelis 2001 Lipid and γ-linolenic acid accumulation in strains of zygomycetes growing on glucose J Am Oil Chem Soc 78 341 346 10.1007/s11746-001-0266-3 1:CAS:528:DC%2BD3MXjt1aqu7g%3D
29. S Khoomrung K Laoteng S Jitsue S Cheevadhanarak 2008 Significance of fatty acid supplementation on profiles of cell growth, fatty acid, and gene expression of three desaturases in Mucor rouxii Appl Microbiol Biotechnol 80 499 506 10.1007/s00253-008-1569-0 1:CAS:528:DC%2BD1cXhtVSjtLbF
30. KE Kwast PV Burke RO Poyton 1998 Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast J Exp Biol 201 1177 1195 1:CAS:528:DyaK1cXjvVOgsLo%3D
31. KE Kwast PV Burke BT Staahl RO Poyton 1999 Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes Proc Natl Acad Sci USA 96 5446 5451 10.1073/pnas.96.10.5446 1:CAS:528:DyaK1MXjtFCnsLg%3D (Pubitemid 29234637)
32. KE Kwast L-C Lai N Menda DT James III S Aref PV Burke 2002 Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: Functional roles of Rox1 and other factors in mediating the anoxic response J Bacteriol 184 250 265 10.1128/JB.184.1.250-265.2002 1:CAS:528:DC%2BD3MXpt1Cmtbs%3D (Pubitemid 34003306)
33. 9-desaturase gene is transcriptionally regulated during cell growth and by low temperature Mol Cell Biol Res Commun 1 36 43 10.1006/mcbr.1999.0107 1:CAS:528:DyaK1MXksFelu74%3D
34. K Laoteng S Jitsue Y Dandusitapunth S Cheevadhanarak 2008 Ethanol-induced changes in expression profiles of cell growth, fatty acid and desaturase genes of Mucor rouxii Fungal Genet Biol 45 61 67 10.1016/j.fgb.2007.04.006 1:CAS:528:DC%2BD2sXhtlamu7bM (Pubitemid 350110405)
35. G Lepage CC Roy 1984 Improved recovery of fatty acid through direct transesterification without prior extraction or purification J Lipid Res 25 1391 1396 1:CAS:528:DyaL2MXpt1egsQ%3D%3D
36. YZ Ming X Di EP Gomez-Sanchez CE Gomez-Sanchez 1994 Improved downward capillary transfer for blotting of DNA and RNA Biotechniques 16 58 59 1:STN:280:DyaK2c7otlGlsw%3D%3D
37. Y Nakagawa A Ueda Y Kaneko S Harashima 2003 Merging of multiple signals regulating Δ9 fatty acid desaturase gene transcription in Saccharomyces cerevisiae Mol Genet Genomics 269 370 380 10.1007/s00438-003-0845-z 1:CAS:528:DC%2BD3sXkvF2gtbs%3D (Pubitemid 36831395)
38. S Papanikolaou M Komaitis G Aggelis 2004 Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media Bioresour Technol 95 287 291 10.1016/j.biortech.2004.02.016 1:CAS:528:DC%2BD2cXmt1Khtbc%3D (Pubitemid 39013369)
39. RO Poyton 1999 Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes Respir Physiol 115 119 133 10.1016/S0034-5687(99)00028-6 1:CAS:528:DyaK1MXisV2hs7Y%3D (Pubitemid 29206478)
40. ER Setiadi T Doedt F Cottier C Noffz JF Ernst 2006 Transcriptional response of Candida albicans to hypoxia: linkage of oxygen sensing and Efg1p-regulatory networks J Mol Biol 361 399 411 10.1016/j.jmb.2006.06.040 1:CAS:528:DC%2BD28Xns1Kisbc%3D (Pubitemid 44118339)
41. ISI Snoek HY Steensma 2007 Factors involved in anaerobic growth of Saccharomyces cerevisiae Yeast 24 1 10 10.1002/yea.1430 1:CAS:528: DC%2BD2sXhtlOhsL0%3D (Pubitemid 46242418)
42. D Somashekar G Venkateshwaran K Sambaiah BR Lokesh 2003 Effect of culture conditions on lipid and gamma-linolenic acid production by mucoraceous fungi Process Biochem 38 1719 1724 10.1016/S0032-9592(02)00258-3 1:CAS:528: DC%2BD3sXlvVKisLk%3D (Pubitemid 36971477)
43. CM Volkmann HP Klein 1983 Stabilization of the yeast desaturase system by low levels of oxygen Orig Life Evol Biosph 13 57 59 10.1007/BF00928764 1:CAS:528:DyaL3sXltlKmsr4%3D
44. OP Ward A Singh 2005 Omega-3/6 fatty acids: Alternative sources of production Process Biochem 40 3627 3652 10.1016/j.procbio.2005.02.020 1:CAS:528:DC%2BD2MXhtFWnt7%2FI (Pubitemid 41446464)
45. DC White AN Tucker 1969 Phospholipid metabolism during changes in the proportions of membrane-bound respiratory pigments in Haemophilus parainfluenzae J Bacteriol 97 199 209 1:CAS:528:DyaF1MXksVarsw%3D%3D
46. RS Zitomer CV Lowry 1992 Regulation of gene expression by oxygen in Saccharomyces cerevisiae Microbiol Mol Biol Rev 56 1 11 1:CAS:528: DyaK38XitlWgt7s%3D