Fork regression is an active helicase-driven pathway in bacteriophage T4

EMBO Reports

Volumn 10, Issue 4, 2009, Pages 394-399

  Long, David T ^a,b   Kreuzer, Kenneth N ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGE DNA; HELICASE; PROTEIN UVSW; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE T4; BIOLOGICAL ACTIVITY; CATALYSIS; CONTROLLED STUDY; DNA METABOLISM; DNA PURIFICATION; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME PURIFICATION; GENE LOCATION; GENE REPRESSION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION;

BACTERIOPHAGE T4; DNA HELICASES; DNA REPLICATION; VIRAL PROTEINS;

EID: 64049087591     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2009.13     Document Type: Article

References (28)

1. Blastyák A, Pintér L, Unk I, Prakash L, Prakash S, Haracska L (2007) Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol Cell 28: 167-175
2. Carles-Kinch K, George JW, Kreuzer KN (1997) Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair, and the regulation of DNA replication origins. EMBO J 16: 4142-4151
3. Courcelle J, Donaldson JR, Chow K-H, Courcelle CT (2003) DNA damage-induced replication fork regression and processing in Escherichia coli. Science 299: 1064-1067
4. Donaldson JR, Courcelle CT, Courcelle J (2006) RuvABC is required to resolve Holliday junctions that accumulate following replication on damaged templates in Escherichia coli. J Biol Chem 281: 28811-28821
5. Fierro-Fernandez M, Hernandez P, Krimer DB, Schvartzman JB (2007) Replication fork reversal occurs spontaneously after digestion but is constrained in supercoiled domains. J Biol Chem 282: 18190-18196
6. Higgins NP, Kato K, Strauss B (1976) A model for replication repair in mammalian cells. J Mol Biol 101: 417-425
7. Kadyrov FA, Drake JW (2004) UvsX recombinase and Dda helicase rescue stalled bacteriophage T4 DNA replication forks in vitro. J Biol Chem 279: 35735-35740
8. Kerr ID, Sivakolundu S, Li Z, Buchsbaum JC, Knox LA, Kriwacki R, White SW (2007) Crystallographic and NMR analyses of UvsW and UvsW.1 from bacteriophage T4. J Biol Chem 282: 34392-34400
9. Kreuzer KN (2000) Recombination-dependent DNA replication in phage T4. Trends Biochem Sci 25: 165-173
10. Li Z, Lu S, Hou G, Ma X, Sheng D, Ni J, Shen Y (2008) Hjm/Hel308A DNA helicase from Sulfolobus tokodaii promotes replication fork regression and interacts with Hjc endonuclease in vitro. J Bacteriol 190: 3006-3017
11. Long DT, Kreuzer KN (2008) Regression supports two mechanisms of fork processing in phage T4. Proc Natl Acad Sci USA 105: 6852-6857
12. Lopes M, Cotta-Ramusino C, Pellicioli A, Liberi G, Plevani P, Muzi-Falconi M, Newlon CS, Foiani M (2001) The DNA replication checkpoint response stabilizes stalled replication forks. Nature 412: 557-561
13. Machwe A, Xiao L, Groden J, Orren DK (2006) The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry 45: 13939-13946
14. Masson ML, Baharoglu Z, Michel B (2008) ruvA and ruvB mutants specifically impaired for replication fork reversal. Mol Microbiol 70: 537-548
15. McGlynn P, Lloyd RG (2002) Genome stability and the processing of damaged replication forks by RecG. Trends Genet 18: 413-419
16. McGlynn P, Lloyd RG, Marians KJ (2001) Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled. Proc Natl Acad Sci USA 98: 8235-8240
17. Meister P, Taddei A, Vernis L, Poidevin M, Gasser SM, Baldacci G (2005) Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol 168: 537-544
18. Michel B, Flores M-J, Viguera E, Grompone G, Seigneur M, Bidnenko V (2001) Rescue of arrested replication forks by homologous recombination. Proc Natl Acad Sci USA 98: 8181-8188
19. Mirkin EV, Mirkin SM (2007) Replication fork stalling at natural impediments. Microbiol Mol Biol Rev 71: 13-35
20. Postow L, Ullsperger C, Keller RW, Bustamante C, Vologodskii AV, Cozzarelli NR (2001) Positive torsional strain causes the formation of a four-way junction at replication forks. J Biol Chem 276: 2790-2796
21. Ralf C, Hickson ID, Wu L (2006) The Bloom's syndrome helicase can promote the regression of a model replication fork. J Biol Chem 281: 22839-22846
22. Robu ME, Inman RB, Cox MM (2001) RecA protein promotes the regression of stalled replication forks in vitro. Proc Natl Acad Sci USA 98 8211-8218
23. Schvartzman JB, Stasiak A (2004) A topological view of the replicon. EMBO J 5: 256-261
24. Seigneur M, Bidnenko V, Ehrlich S, Michel B (1998) RuvAB acts at arrested replication forks. Cell 95: 419-430
25. Selick H, Kreuzer K, Alberts B (1988) The bacteriophage T4 insertion/ substitution vector system. A method for introducing site-specific mutations into the virus chromosome. J Biol Chem 263: 11336-11347
26. Sogo JM, Lopes M, Foiani M (2002) Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297: 599-602
27. Webb MR, Plank JL, Long DT, Hsieh T-s, Kreuzer KN (2007) The phage T4 protein UvsW drives Holliday junction branch migration. J Biol Chem 282: 34401-34411
28. Yoon D, Wang Y, Stapleford K, Wiesmüller L, Chen J (2004) p53 inhibits strand exchange and replication fork regression promoted by human Rad51. J Mol Biol 336: 639-654