Tumor necrosis factor-α polymorphisms in women with idiopathic recurrent miscarriage

Journal of Reproductive Immunology

Volumn 84, Issue 2, 2010, Pages 186-192

  Finan, R R ^a   Al Irhayim, Z ^b   Mustafa, F E ^b   Al Zaman, I ^c   Mohammed, F A ^c   Al Khateeb, G M ^b   Madan, S ^c   Issa, A A ^b,c   Almawi, W Y ^b  

^a SAINT JOSEPH UNIVERSITY   (Lebanon)

^b ARABIAN GULF UNIVERSITY   (Bahrain)

^c Department of Obstetrics and Gynecology ^*  (Bahrain)

Author keywords

Polymorphisms; Recurrent miscarriage; Tumor necrosis factor

Indexed keywords

ADENINE; CYTOSINE; GUANINE; THYMINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PARITY; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; RECURRENT ABORTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ABORTION, HABITUAL; ADULT; ARABS; BAHRAIN; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77049127268     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2009.12.005     Document Type: Article

References (40)

1. Aoki K., Kajiura S., Matsumoto Y., Ogasawara M., Okada S., Yagami Y., and Gleicher N. Preconceptional natural-killer-cell activity as a predictor of miscarriage. Lancet 345 (1995) 1340-1342
2. Babbage S.J., Arkwright P.D., Vince G.S., Perrey C., Pravica V., Quenby S., Bates M., and Hutchinson I.V. Cytokine promoter gene polymorphisms and idiopathic recurrent pregnancy loss. J. Reprod. Immunol. 51 (2001) 21-27
3. Bates M.D., Quenby S., Takakuwa K., Johnson P.M., and Vince G.S. Aberrant cytokine production by peripheral blood mononuclear cells in recurrent pregnancy loss?. Hum. Reprod. 17 (2002) 2439-2444
4. Baxter N., Sumiya M., Cheng S., Erlich H., Regan L., Simons A., and Summerfield J.A. Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin-α genes. Clin. Exp. Immunol. 126 (2001) 529-534
5. Bertolaccini M.L., Atsumi T., Lanchbury J.S., Caliz A.R., Katsumata K., Vaughan R.W., Kondeatis E., Khamashta M.A., Koike T., and Hughes G.R. Plasma tumor necrosis factor alpha levels and the -238*A promoter polymorphism in patients with antiphospholipid syndrome. Thromb. Haemost. 85 (2001) 198-203
6. Borzychowski A.M., Croy B.A., Chan W.L., Redman C.W., and Sargent I.L. Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre-eclampsia may be mediated by natural killer cells. Eur. J. Immunol. 35 (2005) 3054-3063
7. Brown S. Miscarriage and its associations. Semin. Reprod. Med. 26 (2008) 391-400
8. Chae S.J., Kim H., Jee B.C., Suh C.S., Kim S.H., and Kim J.G. Tumor necrosis factor (TNF)-TNF receptor gene polymorphisms and their serum levels in Korean women with endometriosis. Am. J. Reprod. Immunol. 60 (2008) 432-439
9. Choi B.C., Polgar K., Xiao L., and Hill J.A. Progesterone inhibits in-vitro embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss. Hum. Reprod. 15 Suppl. 1 (2000) 46-59
10. Costeas P.A., Koumouli A., Giantsiou-Kyriakou A., Papaloizou A., and Koumas L. Th2/Th3 cytokine genotypes are associated with pregnancy loss. Hum. Immunol. 65 (2004) 135-141
11. Daher S., Shulzhenko N., Morgun A., Mattar R., Rampim G.F., Camano L., and DeLima M.G. Associations between cytokine gene polymorphisms and recurrent pregnancy loss. J. Reprod. Immunol. 58 (2003) 69-77
12. Engel S.A., Erichsen H.C., Savitz D.A., Thorp J., Chanock S.J., and Olshan A.F. Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms. Epidemiology 16 (2005) 469-477
13. Fortunato S.J., Menon R., and Lombardi S.J. Support for an infection induced apoptotic pathway in human fetal membranes. Am. J. Obstet. Gynecol. 184 (2001) 1392-1398
14. Garcia-Lloret M.I., Winkler-Lowen B., and Guilbert L.J. Monocytes adhering by LFA-1 to placental syncytiotrophoblasts induce local apoptosis via release of TNFα. A model for hematogenous initiation of placental inflammations. J. Leukoc. Biol. 68 (2000) 903-908
15. Hanna J., Goldman-Wohl D., Hamani Y., Avraham I., Greenfield C., Natanson-Yaron S., Prus D., Cohen-Daniel L., Arnon T.I., Manaster I., Gazit R., Yutkin V., Benharroch D., Porgador A., Keshet E., Yagel S., and Mandelboim O. Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat. Med. 12 (2006) 1065-1074
16. Hehlgans T., and Pfeffer K. The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games. Immunology 115 (2005) 1-20
17. Hill J.A., Polgar K., and Anderson D.J. T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion. JAMA 273 (1995) 1933-1936
18. Kamali-Sarvestani E., Zolghadri J., Gharesi-Fard B., and Sarvari J. Cytokine gene polymorphisms and susceptibility to recurrent pregnancy loss in Iranian women. J. Reprod. Immunol. 65 (2005) 171-178
19. Koss K., Satsangi J., Fanning G.C., Welsh K.I., and Jewell D.P. Cytokine (TNFα, LTα and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies. Genes Immun. 1 (2000) 185-190
20. Kwak-Kim J.Y., Gilman-Sachs A., and Kim C.E. T helper 1 and 2 immune responses in relationship to pregnancy, nonpregnancy, recurrent spontaneous abortions and infertility of repeated implantation failures. Chem. Immunol. Allergy 88 (2005) 64-79
21. Lashen H., Fear K., and Sturdee D.W. Obesity is associated with increased risk of first trimester and recurrent miscarriage: matched case-control study. Hum. Reprod. 19 (2004) 1644-1646
22. Makhseed M., Raghupathy R., Azizieh F., Omu A., Al-Shamali E., and Ashkanani L. Th1 and Th2 cytokine profiles in recurrent aborters with successful pregnancy and with subsequent abortions. Hum. Reprod. 16 (2001) 2219-2226
23. Pietrowski D., Bettendorf H., Keck C., Burkle B., Unfried G., Riener E.K., Hefler L.A., and Tempfer C. Lack of association of TNFα gene polymorphisms and recurrent pregnancy loss in Caucasian women. J. Reprod. Immunol. 61 (2004) 51-58
24. Prigoshin N., Tambutti M., Larriba J., Gogorza S., and Testa R. Cytokine gene polymorphisms in recurrent pregnancy loss of unknown cause. Am. J. Reprod. Immunol. 52 (2004) 36-41
25. Quenby S., Vince G., Farquharson R., and Aplin J. Recurrent miscarriage: a defect in nature's quality control?. Hum. Reprod. 17 (2002) 1959-1963
26. Raghupathy R. TH1-type immunity is incompatible with successful pregnancy. Immunol. Today 18 (1997) 478-482
27. Raghupathy R., Makhseed M., Azizieh F., Omu A., Gupta M., and Farhat R. Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion. Hum. Reprod. 15 (2000) 713-718
28. Raghupathy R., Al Mutawa E., Makhseed M., Azizieh F., and Szekeres-Bartho J. Modulation of cytokine production by dydrogesterone in lymphocytes from women with recurrent miscarriage. BJOG 112 (2005) 1096-1101
29. Reid J.G., Simpson N.A., Walker R.G., Economidou O., Shillito J., Gooi H.C., Duffy S.R., and Walker J.J. The carriage of pro-inflammatory cytokine gene polymorphisms in recurrent pregnancy loss. Am. J. Reprod. Immunol. 45 (2001) 35-40
30. Saito S., Sakai M., Sasaki Y., Tanebe K., Tsuda H., and Michimata T. Quantitative analysis of peripheral blood Th0, Th1, Th2 and the Th1:Th2 cell ratio during normal human pregnancy and preeclampsia. Clin. Exp. Immunol. 117 (1999) 550-555
31. Sargent I.L., Borzychowski A.M., and Redman C.W. NK cells and human pregnancy-an inflammatory view. Trends Immunol. 27 (2006) 399-404
32. Sierra S., and Stephenson M. Genetics of recurrent pregnancy loss. Semin. Reprod. Med. 24 (2006) 17-24
33. Skoog T., Eriksson P., Hoffstedt J., Ryden M., Hamsten A., and Arner P. Tumour necrosis factor-α (TNFα) polymorphisms -857C/A and -863C/A are associated with TNFα secretion from human adipose tissue. Diabetologia 44 (2001) 654-655
34. Temple R., Aldridge V., Greenwood R., Heyburn P., Sampson M., and Stanley K. Association between outcome of pregnancy and glycaemic control in early pregnancy in type 1 diabetes: population based study. BMJ 325 (2002) 1275-1276
35. Teramoto M., Kitawaki J., Koshiba H., Kitaoka Y., Obayashi H., Hasegawa G., Nakamura N., Yoshikawa T., Matsushita M., Maruya E., et al. Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility. Am. J. Reprod. Immunol. 51 (2004) 352-357
36. Wegmann T.G., Lin H., Guilbert L., and Mosmann T.R. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?. Immunol. Today 14 (1993) 353-356
37. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., and Duff G.W. Effects of a polymorphism in the human tumor necrosis factor a promoter on transcriptional activation. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 3195-3199
38. Yamada H., Kato E.H., Kobashi G., Ebina Y., Shimada S., Morikawa M., Sakuragi N., and Fujimoto S. High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion. Am. J. Reprod. Immunol. 46 (2001) 132-136
39. Zammiti W., Mtiraoui N., Finan R.R., Almawi W.Y., and Mahjoub T. Tumor necrosis factor alpha and lymphotoxin alpha haplotypes in idiopathic recurrent pregnancy loss. Fertil. Steril. 91 (2009) 1903-1908
40. Zhu X.Y., Zhou Y.H., Wang M.Y., Jin L.P., Yuan M.M., and Li D.J. Blockade of CD86 signaling facilitates a Th2 bias at the maternal-fetal interface and expands peripheral CD4+CD25+ regulatory T cells to rescue abortion-prone fetuses. Biol. Reprod. 72 (2005) 338-345