Lack of association of TNFα gene polymorphisms and recurrent pregnancy loss in Caucasian women

Journal of Reproductive Immunology

Volumn 61, Issue 1, 2004, Pages 51-58

  Pietrowski, Detlef ^a   Bettendorf, Herta ^a   Keck, Christoph ^a   Bürkle, Bernd ^a   Unfried, Gertrud ^b   Riener, Eva Katrin ^a   Hefler, Lukas A ^b   Tempfer, Clemens ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Genetic study; Miscarriage; Polymorphism; Pregnancy; TNF

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; RECURRENT ABORTION; AGED; ALLELE; CASE CONTROL STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PREGNANCY; SINGLE NUCLEOTIDE POLYMORPHISM;

ABORTION, HABITUAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PROMOTER REGIONS (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 1142285363     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2003.12.001     Document Type: Article

References (22)

1. Babbage S.J., Arkwright P.D., Vince G.S., Perrey C., Pravica V., Quenby S., Bates M., Hutchinson I.V. Cytokine promoter gene polymorphisms and idiopathic recurrent pregnancy loss. J. Reprod. Immunol. 51:2001;21-27.
2. Bathgate A.J., Pravica V., Perrey C., Therapondos G., Plevris J.N., Hayes P.C., Hutchinson I.V. The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection. Transplantation. 69:2000;1514-1517.
3. Carey J.C., Klebanoff M.A., Hauth J.C., Hillier S.L., Thom E.A., Ernest J.M., Heine R.P., Nugent R.P., Fischer M.L., Leveno K.J., Wapner R., Varner M. Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Foetal Medicine Units. N. Engl. J. Med. 342:2000;534-540.
4. Daher S., Fonseca F., Ribeiro O.G., Musatti C.C., Gerbase-DeLima M. Tumor necrosis factor during pregnancy and at the onset of labor and spontaneous abortion. Eur. J. Obstet. Gynecol. Biol. 83:1999;77-79.
5. Daher S., Shulzhenko N., Morgun A., Mattar R., Rampim G.F., Camano L., DeLima M.G. Associations between cytokine gene polymorphisms and recurrent pregnancy loss. J. Reprod. Immunol. 58:2003;69-77.
6. Hill J.A., Choi B.C. Maternal immunological aspects of pregnancy success and failure. J. Reprod. Fertil. Suppl. 55:2000;91-97.
7. Hill J.A., Polgar K., Anderson D.J. T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion. JAMA. 273:1995;1933-1936.
8. Jenkins C., Roberts J., Wilson R., MacLean M.A., Shilito J., Walker J.J. Evidence of a T(H) 1 type response associated with recurrent miscarriage. Fertil. Steril. 73:2000;1206-1208.
9. McDonald H.M., O'Loughlin J.A., Vigneswaran R., Jolley P.T., Harvey J.A., Bof A., McDonald P.J. Impact of metronidazole therapy on preterm birth in women with bacterial vaginosis flora (Gardnerella vaginalis): a randomised, placebo controlled trial. Br. J. Obstet. Gynaecol. 104:1997;1391-1397.
10. Mueller-Eckhardt G., Mallmann P., Neppert J., Lattermann A., Melk A., Heine O., Pfeiffer R., Zingsem J., Domke N., Mohr-Pennert A. Immunogenetic and serological investigations in nonpregnant and in pregnant women with a history of recurrent spontaneous abortions. German RSA/WIG Study Group. J. Reprod. Immunol. 27:1994;95-109.
11. Muc-Wierzgon M., Madej K., Baranowski M., Wierzgon J. Circadian rhythmometry of serum endogenous tumor necrosis factor-alpha in patients with colorectal cancer metastases. Eur. Cytokine Netw. 9:1998;193-196.
12. Muc-Wierzgon M., Baranowski M.M., Madej K., Wierzgon J., Kokot T., Brodziak A. Dynamics of diurnal changes in serum concentration of TNF-alpha soluble receptors in gastrointestinal cancer patients. J. Biol. Regul. Homeost. Agents. 14:2000;204-208.
13. Ng S.C., Gilman-Sachs A., Thaker P., Beaman K.D., Beer A.E., Kwak-Kim J. Expression of intracellular Th1 and Th2 cytokines in women with recurrent spontaneous abortion, implantation failures after IVF/ET or normal pregnancy. Am. J. Reprod. Immunol. 48:2002;77-86.
14. Quenby S., Vince G., Farquharson R., Aplin J. Recurrent miscarriage: a defect in nature's quality control? Hum. Reprod. 17:2002;1959-1963.
15. Raghupathy R., Makhseed M., Azizieh F., Hassan N., Al Azemi M., Al Shamali E. Maternal Th1- and Th2-type reactivity to placental antigens in normal human pregnancy and unexplained recurrent spontaneous abortions. Cell Immunol. 196:1999;122-130.
16. Raghupathy R., Makhseed M., Azizieh F., Omu A., Gupta M., Farhat R. Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion. Hum. Reprod. 15:2000;713-718.
17. Reid J.G., Simpson N.A., Walker R.G., Economidou O., Shillito J., Gooi H.C., Duffy S.R., Walker J.J. The carriage of pro-inflammatory cytokine gene polymorphisms in recurrent pregnancy loss. Am. J. Reprod. Immunol. 45:2001;35-40.
18. Schaaf B.M., Seitzer U., Pravica V., Aries S.P., Zabel P. Tumor necrosis factor-alpha -308 promoter gene polymorphism and increased tumor necrosis factor serum bioactivity in farmer's lung patients. Am. J. Respir. Crit. Care Med. 163:2001;379-382.
19. Skoog T., van't Hooft F.M., Kallin B., Jovinge S., Boquist S., Nilsson J., Eriksson P., Hamsten A. A common functional polymorphism (. C→A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha Hum. Mol. Genet. 8:1999;1443-1449.
20. Stephenson M.D. Frequency of factors associated with habitual abortion in 197 couples. Fertil. Steril. 66:1996;24-29.
21. Wennberg P., Nordstrom P., Lorentzon R., Lerner U.H., Lorentzon M. TNF-alpha gene polymorphism and plasma TNF-alpha levels are related to lumbar spine bone area in healthy female Caucasian adolescents. Eur. J. Endocrinol. 146:2002;629-634.
22. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., Duff G.W. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc. Natl. Acad. Sci. U.S.A. 94:1997;3195-3199.