-
1
-
-
0009841834
-
Protective effect of bicyclol on concanavalin A induced liver nuclei DNA injury in mice
-
Zhao DM, Liu GT. Protective effect of bicyclol on concanavalin A induced liver nuclei DNA injury in mice. Natl Med J China 2001; 81: 844-848
-
(2001)
Natl Med J China
, vol.81
, pp. 844-848
-
-
Zhao, D.M.1
Liu, G.T.2
-
2
-
-
0001012455
-
Effect of bicyclol on acetaminophen-induced hepatotoxicity: Energetic metabolism and mitochondrial injury in acetaminophen-intoxicated mice
-
Li Y, Dai GW, Li Y, Liu GT. Effect of bicyclol on acetaminophen-induced hepatotoxicity: energetic metabolism and mitochondrial injury in acetaminophen-intoxicated mice. Yao Xue Xue Bao 2001; 36: 723-726
-
(2001)
Yao Xue Xue Bao
, vol.36
, pp. 723-726
-
-
Li, Y.1
Dai, G.W.2
Li, Y.3
Liu, G.T.4
-
3
-
-
22844437516
-
Mechanism of protective action of bicyclol against CCl4-induced liver injury in mice
-
Liu GT, Li Y, Wei HL, Zhang H, Xu JY, Yu LH. Mechanism of protective action of bicyclol against CCl4-induced liver injury in mice. Liver Int 2005; 25: 872-879
-
(2005)
Liver Int
, vol.25
, pp. 872-879
-
-
Liu, G.T.1
Li, Y.2
Wei, H.L.3
Zhang, H.4
Xu, J.Y.5
Yu, L.H.6
-
4
-
-
0009867189
-
The anti-virus and hepatoprotective effect of bicyclol and its mechanism of action
-
Liu GT. The anti-virus and hepatoprotective effect of bicyclol and its mechanism of action. Chin J New Drugs 2001; 10: 325-327
-
(2001)
Chin J New Drugs
, vol.10
, pp. 325-327
-
-
Liu, G.T.1
-
5
-
-
3142742390
-
A randomized double-blind controlled trial of bicyclol in treatment of chronic hepatitis B
-
Yao GB, Ji YY, Wang QH, Zhou XQ, Xu DZ, Chen XY, et al. A randomized double-blind controlled trial of bicyclol in treatment of chronic hepatitis B. Chin J New Drugs Clin Rem 2002; 21: 457-462
-
(2002)
Chin J New Drugs Clin Rem
, vol.21
, pp. 457-462
-
-
Yao, G.B.1
Ji, Y.Y.2
Wang, Q.H.3
Zhou, X.Q.4
Xu, D.Z.5
Chen, X.Y.6
-
6
-
-
33644927143
-
Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride
-
Li Y, Li Y, Liu GT. Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride. Natl Med J China 2004; 84: 2096-2101
-
(2004)
Natl Med J China
, vol.84
, pp. 2096-2101
-
-
Li, Y.1
Li, Y.2
Liu, G.T.3
-
7
-
-
62649142429
-
Bicyclol: A novel drug for treating chronic viral hepatitis B and C
-
Liu GT. Bicyclol: a novel drug for treating chronic viral hepatitis B and C. Med Chem 2009; 5: 29-43.
-
(2009)
Med Chem
, vol.5
, pp. 29-43
-
-
Liu, G.T.1
-
8
-
-
0027522356
-
Cells in stress: Transcriptional activation of heat shock genes
-
Morimoto RI. Cells in stress: transcriptional activation of heat shock genes. Science 1993; 259: 1409-1410
-
(1993)
Science
, vol.259
, pp. 1409-1410
-
-
Morimoto, R.I.1
-
9
-
-
0041816199
-
Heat shock protein 27 association with the I-kappa B kinase complex regulates tumor necrosis factor alphainduced NF-kappa B activation
-
Park KJ, Gaynor RB, Kwak YT. Heat shock protein 27 association with the I-kappa B kinase complex regulates tumor necrosis factor alphainduced NF-kappa B activation. J Biol Chem 2003; 278: 35272-35278
-
(2003)
J Biol Chem
, vol.278
, pp. 35272-35278
-
-
Park, K.J.1
Gaynor, R.B.2
Kwak, Y.T.3
-
10
-
-
1542298849
-
Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury
-
Sumioka I, Matsura T, Kai M, Yamada K. Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury. Life Sci 2004; 74: 2551-2561
-
(2004)
Life Sci
, vol.74
, pp. 2551-2561
-
-
Sumioka, I.1
Matsura, T.2
Kai, M.3
Yamada, K.4
-
11
-
-
0036401407
-
Immunohistochemical studies on the expression pattern of molecular chaperones HSC70 and HSP25 and cell cycle-related proteins cyclin D1 and PCNA in rat liver after thioacetamide intoxication
-
Zborek A, Ma?usecka E, Krzyowska-Gruca S, Wysocka A, Krawczyk Z. Immunohistochemical studies on the expression pattern of molecular chaperones HSC70 and HSP25 and cell cycle-related proteins cyclin D1 and PCNA in rat liver after thioacetamide intoxication. Histochem Cell Biol 2002; 118: 311-319
-
(2002)
Histochem Cell Biol
, vol.118
, pp. 311-319
-
-
Zborek, A.1
Mausecka, E.2
Krzyowska-Gruca, S.3
Wysocka, A.4
Krawczyk, Z.5
-
13
-
-
0034030613
-
TNF-alpha but not Il-1alpha are correlated with PGE1-dependent protection against acute D-galactosamine-induced liver injury
-
Muntane J, Montero JL, Lozano JM, Miranda-Vizuete A, de la Mata M, Mino G. TNF-alpha but not Il-1alpha are correlated with PGE1-dependent protection against acute D-galactosamine-induced liver injury. Can J Gastroenterol 2000; 14: 175-180
-
(2000)
Can J Gastroenterol
, vol.14
, pp. 175-180
-
-
Muntane, J.1
Montero, J.L.2
Lozano, J.M.3
Miranda-Vizuete, A.4
De La Mata, M.5
Mino, G.6
-
14
-
-
3142754211
-
Role of NF-kappaB activation and nitric oxide expression during PGE protection against d-galactosamine-induced cell death in cultured rat hepatocytes
-
Fouad D, Siendones E, Costán G, Muntané J. Role of NF-kappaB activation and nitric oxide expression during PGE protection against d-galactosamine-induced cell death in cultured rat hepatocytes. Liver Int 2004; 24: 227-236
-
(2004)
Liver Int
, vol.24
, pp. 227-236
-
-
Fouad, D.1
Siendones, E.2
Costán, G.3
Muntané, J.4
-
15
-
-
53149089104
-
Bicyclol: A novel antihepatitis drug with hepatic heat shock protein 27/70-inducing activity and cytoprotective effects in mice
-
Bao XQ, Liu GT. Bicyclol: a novel antihepatitis drug with hepatic heat shock protein 27/70-inducing activity and cytoprotective effects in mice. Cell Stress Chaperones 2008; 13: 347-355
-
(2008)
Cell Stress Chaperones
, vol.13
, pp. 347-355
-
-
Bao, X.Q.1
Liu, G.T.2
-
16
-
-
66049162280
-
Induction of heat shock protein 27 and 70 overexpression by bicyclol attenuates concanavalin A-induced liver injury through suppression of NF-{kappa}B in mice
-
Bao XQ, Liu GT. Induction of heat shock protein 27 and 70 overexpression by bicyclol attenuates concanavalin A-induced liver injury through suppression of NF-{kappa}B in mice. Mol Pharmacol 2009; 75: 1180-1188
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1180-1188
-
-
Bao, X.Q.1
Liu, G.T.2
-
17
-
-
0026492817
-
Features of apoptotic cells measured by flow cytometry
-
Darzynkiewicz Z, Bruno S, Del Bino G, Gorczyca W, Hotz MA, Lassota P, et al. Features of apoptotic cells measured by flow cytometry. Cytometry 1992; 13: 795-808.
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Bruno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
-
18
-
-
0033990336
-
Heat shock factors and the control of the stress response
-
Santoro MG. Heat shock factors and the control of the stress response. Biochem Pharmacol 2000; 59: 55-63.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 55-63
-
-
Santoro, M.G.1
-
19
-
-
0035910574
-
Implication of a small GTPase Rac1 in the activation of c-Jun N-terminal kinase and heat shock factor in response to heat shock
-
Han SI, Oh SY, Woo SH, Kim KH, Kim JH, Kim HD, et al. Implication of a small GTPase Rac1 in the activation of c-Jun N-terminal kinase and heat shock factor in response to heat shock. J Biol Chem 2001; 276: 1889-1895
-
(2001)
J Biol Chem
, vol.276
, pp. 1889-1895
-
-
Han, S.I.1
Oh, S.Y.2
Woo, S.H.3
Kim, K.H.4
Kim, J.H.5
Kim, H.D.6
-
20
-
-
54449091313
-
Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis
-
Wang WH, Hullinger RL, Andrisani OM. Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis. J Biol Chem 2008; 283: 25455-25467
-
(2008)
J Biol Chem
, vol.283
, pp. 25455-25467
-
-
Wang, W.H.1
Hullinger, R.L.2
Andrisani, O.M.3
-
21
-
-
48049090288
-
Liver apoptosis following normothermic ischemia-reperfusion: In vivo evaluation of caspase activity by FLIVO assay in rats
-
Cursio R, Colosetti P, Auberger P, Gugenheim J. Liver apoptosis following normothermic ischemia-reperfusion: in vivo evaluation of caspase activity by FLIVO assay in rats. Transplant Proc 2008; 40: 2038-2041
-
(2008)
Transplant Proc
, vol.40
, pp. 2038-2041
-
-
Cursio, R.1
Colosetti, P.2
Auberger, P.3
Gugenheim, J.4
-
23
-
-
33644524120
-
Apoptosis and necrosis in the liver: A tale of two deaths?
-
Malhi H, Gores GJ, Lemasters JJ. Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology 2006; 43: S31-S44.
-
(2006)
Hepatology
, vol.43
-
-
Malhi, H.1
Gores, G.J.2
Lemasters, J.J.3
-
24
-
-
33847026754
-
Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons
-
Wright KM, Vaughn AE, Deshmukh M. Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons. Cell Death Differ 2007; 14: 625-633
-
(2007)
Cell Death Differ
, vol.14
, pp. 625-633
-
-
Wright, K.M.1
Vaughn, A.E.2
Deshmukh, M.3
-
25
-
-
0035967169
-
Essential role of the mitochondrial apoptosis inducing factor in programmed cell death
-
Joza N, Susin SA, Daugas E, Stanford W, Cho SK, Li CY, et al. Essential role of the mitochondrial apoptosis inducing factor in programmed cell death. Nature 2001; 410: 549-554
-
(2001)
Nature
, vol.410
, pp. 549-554
-
-
Joza, N.1
Susin, S.A.2
Daugas, E.3
Stanford, W.4
Cho, S.K.5
Li, C.Y.6
-
26
-
-
0033516660
-
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation
-
Rogalla T, Ehrnsperger M, Preville X, Kotlyarov A, Lutsch G, Ducasse C, et al. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem 1999; 274: 18947-18956
-
(1999)
J Biol Chem
, vol.274
, pp. 18947-18956
-
-
Rogalla, T.1
Ehrnsperger, M.2
Preville, X.3
Kotlyarov, A.4
Lutsch, G.5
Ducasse, C.6
-
27
-
-
0034282104
-
Hsp27 negatively regulates cell death by interacting with cytochrome c
-
Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, et al. Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2000; 2: 645-652
-
(2000)
Nat Cell Biol
, vol.2
, pp. 645-652
-
-
Bruey, J.M.1
Ducasse, C.2
Bonniaud, P.3
Ravagnan, L.4
Susin, S.A.5
Diaz-Latoud, C.6
-
28
-
-
0036252442
-
The effect of quercetin on the expression of heat shock proteins and apoptosis induction in monkey kidney cell line GMK
-
Jakubowicz-Gil J, Rzymowska J, Paduch R, Gawron A. The effect of quercetin on the expression of heat shock proteins and apoptosis induction in monkey kidney cell line GMK. Folia Histochem Cytobio 2002; 40: 137-138
-
(2002)
Folia Histochem Cytobio
, vol.40
, pp. 137-138
-
-
Jakubowicz-Gil, J.1
Rzymowska, J.2
Paduch, R.3
Gawron, A.4
-
29
-
-
0345538683
-
Geranylgeranylacetone attenuates septic diaphragm dysfunction by induction of heat shock protein 70
-
Masuda Y, Sumita S, Fujimura N, Namiki A. Geranylgeranylacetone attenuates septic diaphragm dysfunction by induction of heat shock protein 70. Crit Care Med 2003; 31: 2585-2591
-
(2003)
Crit Care Med
, vol.31
, pp. 2585-2591
-
-
Masuda, Y.1
Sumita, S.2
Fujimura, N.3
Namiki, A.4
-
30
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, et al. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 2001; 3: 839-843
-
(2001)
Nat Cell Biol
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
Maisse, C.4
Daugas, E.5
Zamzami, N.6
-
31
-
-
33749554554
-
Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro
-
Rocchi P, Jugpal P, So A, Sinneman S, Ettinger S, Fazli L, et al. Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro. BJU Int 2006; 98: 1082-1089
-
(2006)
BJU Int
, vol.98
, pp. 1082-1089
-
-
Rocchi, P.1
Jugpal, P.2
So, A.3
Sinneman, S.4
Ettinger, S.5
Fazli, L.6
-
32
-
-
0032722324
-
HSP27 inhibits cytochrome c-dependent activation of procaspase-9
-
Garrido C, Bruey JM, Fromentin A, Hammann A, Arrigo AP, Solary E. HSP27 inhibits cytochrome c-dependent activation of procaspase-9. Faseb J 1999;13: 2061-2070
-
(1999)
Faseb J
, vol.13
, pp. 2061-2070
-
-
Garrido, C.1
Bruey, J.M.2
Fromentin, A.3
Hammann, A.4
Arrigo, A.P.5
Solary, E.6
-
33
-
-
34249789027
-
Regulation of hepatocyte apoptosis by oxidative stress
-
Singh R, Czaja MJ. Regulation of hepatocyte apoptosis by oxidative stress. J Gastroenterol Hepatol 2007; 22 Suppl 1: S45-48.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, Issue.SUPPL. 1
-
-
Singh, R.1
Czaja, M.J.2
-
34
-
-
14844327760
-
Reactive oxygen species promote TNF-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNF-?-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005; 120: 649-661
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
35
-
-
0038452604
-
Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation
-
Nakagomi S, Suzuki Y, Namikawa K, Kiryu-Seo S, Kiyama H. Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation. J Neurosci 2003; 23: 5187-5196
-
(2003)
J Neurosci
, vol.23
, pp. 5187-5196
-
-
Nakagomi, S.1
Suzuki, Y.2
Namikawa, K.3
Kiryu-Seo, S.4
Kiyama, H.5
|