메뉴 건너뛰기




Volumn 22, Issue 3, 2010, Pages 197-204

LPS mediated injury to oligodendrocytes is mediated by the activation of nNOS: Relevance to human demyelinating disease

Author keywords

Demyelination; iNOS; LPS; nNOS; Oligodendrocyte

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOCHONDRIAL PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; TOLL LIKE RECEPTOR;

EID: 76949093337     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2009.12.001     Document Type: Article
Times cited : (20)

References (55)
  • 1
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
    • Barnett M.H., and Prineas J.W. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55 (2004) 458-468
    • (2004) Ann. Neurol. , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 2
    • 27444444869 scopus 로고    scopus 로고
    • The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage
    • Bruck W. The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage. J. Neurol. 252 Suppl. 5 (2005) v3-v9
    • (2005) J. Neurol. , vol.252 , Issue.SUPPL. 5
    • Bruck, W.1
  • 3
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A., and Coles A. Multiple sclerosis. Lancet 372 (2008) 1502-1517
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 4
    • 0025827448 scopus 로고
    • Cytokine cytotoxicity against oligodendrocytes: apoptosis induced by lymphotoxin
    • Selmaj K., Raine C.S., Farooq M., and Brosnan C. Cytokine cytotoxicity against oligodendrocytes: apoptosis induced by lymphotoxin. J. Immunol. 147 (1991) 1522-1530
    • (1991) J. Immunol. , vol.147 , pp. 1522-1530
    • Selmaj, K.1    Raine, C.S.2    Farooq, M.3    Brosnan, C.4
  • 5
    • 0029410743 scopus 로고
    • Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis
    • Vartanian T., Li Y., Zhao M., and Stefansson K. Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol. Med. 1 (1995) 732-743
    • (1995) Mol. Med. , vol.1 , pp. 732-743
    • Vartanian, T.1    Li, Y.2    Zhao, M.3    Stefansson, K.4
  • 6
    • 0027082393 scopus 로고
    • Interaction between oligodendrocyte and microglia: a major role for complementing oligodendrocyte adherence and killing
    • Zajisek J.P., Wing M.G., Scolding N., and Compston D.A.S. Interaction between oligodendrocyte and microglia: a major role for complementing oligodendrocyte adherence and killing. Brain 115 (1992) 1611-1631
    • (1992) Brain , vol.115 , pp. 1611-1631
    • Zajisek, J.P.1    Wing, M.G.2    Scolding, N.3    Compston, D.A.S.4
  • 8
    • 0033559981 scopus 로고    scopus 로고
    • Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis
    • Cua D.J., Groux H., Hinton D.R., Stohlman S.A., and Coffman R.L. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. J. Exp. Med. 189 (1999) 1005-1010
    • (1999) J. Exp. Med. , vol.189 , pp. 1005-1010
    • Cua, D.J.1    Groux, H.2    Hinton, D.R.3    Stohlman, S.A.4    Coffman, R.L.5
  • 9
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy
    • Akassoglou K., Bauer J., Kassiotis G., Pasparakis M., Lassmann H., Kollias G., and Probert L. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am. J. Pathol. 153 (1998) 801-813
    • (1998) Am. J. Pathol. , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassmann, H.5    Kollias, G.6    Probert, L.7
  • 10
    • 34250186821 scopus 로고    scopus 로고
    • Contrasting potential of nitric oxide and peroxynitrite to mediate oligodendrocyte injury in multiple sclerosis
    • Jack C., Antel J., Bruck W., and Kuhlmann T. Contrasting potential of nitric oxide and peroxynitrite to mediate oligodendrocyte injury in multiple sclerosis. Glia 55 (2007) 926-934
    • (2007) Glia , vol.55 , pp. 926-934
    • Jack, C.1    Antel, J.2    Bruck, W.3    Kuhlmann, T.4
  • 11
    • 8144222287 scopus 로고    scopus 로고
    • Nitric oxide-induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis-inducing factor translocation
    • Baud O., Li J., Zhang Y., Neve R.L., Volpe J.J., and Rosenberg P.A. Nitric oxide-induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis-inducing factor translocation. Eur. J. Neurosci. 20 (2004) 1713-1726
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1713-1726
    • Baud, O.1    Li, J.2    Zhang, Y.3    Neve, R.L.4    Volpe, J.J.5    Rosenberg, P.A.6
  • 12
    • 0344012010 scopus 로고    scopus 로고
    • Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion
    • Borutaite V., and Brown G.C. Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion. Free Radic. Biol. Med. 35 (2003) 1457-1468
    • (2003) Free Radic. Biol. Med. , vol.35 , pp. 1457-1468
    • Borutaite, V.1    Brown, G.C.2
  • 13
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide Glutamate, and mitochondria
    • Brown G.C., and Bal-Price A. Inflammatory neurodegeneration mediated by nitric oxide Glutamate, and mitochondria. Mol. Neurobiol. 27 (2003) 325-355
    • (2003) Mol. Neurobiol. , vol.27 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 15
    • 0032789444 scopus 로고    scopus 로고
    • Nitric oxide: a unique endogenous signaling molecule in vascular biology
    • Ignarro L.J. Nitric oxide: a unique endogenous signaling molecule in vascular biology. Biosci. Rep. 19 (1999) 51-71
    • (1999) Biosci. Rep. , vol.19 , pp. 51-71
    • Ignarro, L.J.1
  • 16
    • 0032707717 scopus 로고    scopus 로고
    • Nitric oxide as a signaling molecule in the vascular system: an overview
    • Ignarro L.J., Cirino G., Casini A., and Napoli C. Nitric oxide as a signaling molecule in the vascular system: an overview. J. Cardiovasc. Pharmacol. 34 (1999) 879-886
    • (1999) J. Cardiovasc. Pharmacol. , vol.34 , pp. 879-886
    • Ignarro, L.J.1    Cirino, G.2    Casini, A.3    Napoli, C.4
  • 18
    • 34249811810 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide synthase
    • Ghafourifar P., and Sen C.K. Mitochondrial nitric oxide synthase. Front. Biosci. 12 (2007) 1072-1078
    • (2007) Front. Biosci. , vol.12 , pp. 1072-1078
    • Ghafourifar, P.1    Sen, C.K.2
  • 21
    • 67349230279 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase: structure localization and clinical implications
    • Zhou L., and Zhu D.-Y. Neuronal nitric oxide synthase: structure localization and clinical implications. Nitric Oxide 20 (2009) 223-230
    • (2009) Nitric Oxide , vol.20 , pp. 223-230
    • Zhou, L.1    Zhu, D.-Y.2
  • 22
    • 64949128852 scopus 로고    scopus 로고
    • Differences in c-jun and nNOS expression levels in motoneurons following different kinds of axonal injury in adult rats
    • Zhou L.H., Han S., Xie Y.Y., Wang L.L., and Yao Z.B. Differences in c-jun and nNOS expression levels in motoneurons following different kinds of axonal injury in adult rats. Brain Cell Biol. 36 (2008) 213-227
    • (2008) Brain Cell Biol. , vol.36 , pp. 213-227
    • Zhou, L.H.1    Han, S.2    Xie, Y.Y.3    Wang, L.L.4    Yao, Z.B.5
  • 23
    • 33745840525 scopus 로고    scopus 로고
    • Nitric oxide synthase expression and nitric oxide toxicity in oligodendrocytes
    • Boullerne A.I., and Benjamins J.A. Nitric oxide synthase expression and nitric oxide toxicity in oligodendrocytes. Antioxid. Redox Signal. 8 (2006) 967-980
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 967-980
    • Boullerne, A.I.1    Benjamins, J.A.2
  • 25
    • 13844250617 scopus 로고    scopus 로고
    • Evidence of nitrosative damage in the brain white matter of patients with multiple sclerosis
    • Bizzozero O.A., DeJesus G., Bixler H.A., and Pastuszyn A. Evidence of nitrosative damage in the brain white matter of patients with multiple sclerosis. Neurochem. Res. 30 (2005) 139-149
    • (2005) Neurochem. Res. , vol.30 , pp. 139-149
    • Bizzozero, O.A.1    DeJesus, G.2    Bixler, H.A.3    Pastuszyn, A.4
  • 27
    • 34547120440 scopus 로고    scopus 로고
    • Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis
    • Rejdak K., Petzold A., Kocki T., Kurzepa J., Grieb P., Turski W.A., and Stelmasiak Z. Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis. J. Neural Transm. 114 (2007) 1011-1015
    • (2007) J. Neural Transm. , vol.114 , pp. 1011-1015
    • Rejdak, K.1    Petzold, A.2    Kocki, T.3    Kurzepa, J.4    Grieb, P.5    Turski, W.A.6    Stelmasiak, Z.7
  • 28
    • 33745807628 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase gene in glial cells
    • Saha R.N., and Pahan K. Regulation of inducible nitric oxide synthase gene in glial cells. Antioxid. Redox Signal. 8 (2006) 929-947
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 929-947
    • Saha, R.N.1    Pahan, K.2
  • 32
    • 0028812265 scopus 로고
    • A human glial hybrid cell line differentially expressing genes subserving oligodendrocyte and astrocyte phenotype
    • McLaurin J., Trudel G.C., Shaw I.T., Antel J.P., and Cashman N.R. A human glial hybrid cell line differentially expressing genes subserving oligodendrocyte and astrocyte phenotype. J. Neurobiol. 26 (1995) 283-293
    • (1995) J. Neurobiol. , vol.26 , pp. 283-293
    • McLaurin, J.1    Trudel, G.C.2    Shaw, I.T.3    Antel, J.P.4    Cashman, N.R.5
  • 33
    • 27144501566 scopus 로고    scopus 로고
    • Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes
    • Ahlqvist J., Fotheringham J., Akhyani N., Yao K., Fogdell-Hahn A., and Jacobson S. Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. J. Neurovirol. 11 (2005) 384-394
    • (2005) J. Neurovirol. , vol.11 , pp. 384-394
    • Ahlqvist, J.1    Fotheringham, J.2    Akhyani, N.3    Yao, K.4    Fogdell-Hahn, A.5    Jacobson, S.6
  • 34
    • 43649105315 scopus 로고    scopus 로고
    • Molecular mechanisms of Fas-mediated cell death in oligodendrocytes
    • Austin J.W., and Fehlings M.G. Molecular mechanisms of Fas-mediated cell death in oligodendrocytes. J. Neurotrauma 25 (2008) 411-426
    • (2008) J. Neurotrauma , vol.25 , pp. 411-426
    • Austin, J.W.1    Fehlings, M.G.2
  • 35
    • 43549092043 scopus 로고    scopus 로고
    • The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease
    • Giri S., Khan M., Nath N., Singh I., and Singh A.K. The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease. J. Neurochem. 105 (2008) 1820-1833
    • (2008) J. Neurochem. , vol.105 , pp. 1820-1833
    • Giri, S.1    Khan, M.2    Nath, N.3    Singh, I.4    Singh, A.K.5
  • 36
    • 40749163172 scopus 로고    scopus 로고
    • Involvement of CAPON and nitric oxide synthases in rat muscle regeneration after peripheral nerve injury
    • Chen M., Cheng C., Yan M., Niu S., Gao S., Shi S., Liu H., Qin Y., and Shen A. Involvement of CAPON and nitric oxide synthases in rat muscle regeneration after peripheral nerve injury. J. Mol. Neurosci. 34 (2008) 89-100
    • (2008) J. Mol. Neurosci. , vol.34 , pp. 89-100
    • Chen, M.1    Cheng, C.2    Yan, M.3    Niu, S.4    Gao, S.5    Shi, S.6    Liu, H.7    Qin, Y.8    Shen, A.9
  • 38
    • 62049085922 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase promotes facial axonal regeneration following neurography
    • Wang S.M., Tsai H.P., Huang J.J., Huang H.C., Lin J.L., and Liu P.H. Inhibition of nitric oxide synthase promotes facial axonal regeneration following neurography. Exp. Neurol. 216 (2009) 499-510
    • (2009) Exp. Neurol. , vol.216 , pp. 499-510
    • Wang, S.M.1    Tsai, H.P.2    Huang, J.J.3    Huang, H.C.4    Lin, J.L.5    Liu, P.H.6
  • 39
  • 40
    • 0000661219 scopus 로고    scopus 로고
    • Tissue- and development-specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase
    • Lee M.A., Cai L., Hubner N., Lee Y.A., and Lindpaintner K. Tissue- and development-specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase. J. Clin. Invest. 100 (1997) 1507-1512
    • (1997) J. Clin. Invest. , vol.100 , pp. 1507-1512
    • Lee, M.A.1    Cai, L.2    Hubner, N.3    Lee, Y.A.4    Lindpaintner, K.5
  • 41
    • 33845327490 scopus 로고    scopus 로고
    • Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology
    • Giulivi C., Kato K., and Cooper C.E. Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology. Am. J. Physiol. Cell Physiol. 291 (2006) C1225-C1231
    • (2006) Am. J. Physiol. Cell Physiol. , vol.291
    • Giulivi, C.1    Kato, K.2    Cooper, C.E.3
  • 43
    • 46849122006 scopus 로고    scopus 로고
    • Mitochondrial defects in acute multiple sclerosis lesions
    • Mahad D., Ziabreva I., Lassmann H., and Turnbull D. Mitochondrial defects in acute multiple sclerosis lesions. Brain 131 (2008) 1722-1735
    • (2008) Brain , vol.131 , pp. 1722-1735
    • Mahad, D.1    Ziabreva, I.2    Lassmann, H.3    Turnbull, D.4
  • 44
    • 37549070224 scopus 로고    scopus 로고
    • Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
    • Zeis T., Graumann U., Reynolds R., and Schaeren-Wiemers N. Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. Brain 131 (2008) 288-303
    • (2008) Brain , vol.131 , pp. 288-303
    • Zeis, T.1    Graumann, U.2    Reynolds, R.3    Schaeren-Wiemers, N.4
  • 45
    • 66949152122 scopus 로고    scopus 로고
    • Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis
    • Zeis T., Probst A., Steck A.J., Stadelmann C., Bruck W., and Schaeren-Wiemers N. Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain Pathol. 19 (2008) 459-466
    • (2008) Brain Pathol. , vol.19 , pp. 459-466
    • Zeis, T.1    Probst, A.2    Steck, A.J.3    Stadelmann, C.4    Bruck, W.5    Schaeren-Wiemers, N.6
  • 47
    • 45949112049 scopus 로고    scopus 로고
    • Lame ducks or fierce creatures? The role of oligodendrocytes in multiple sclerosis
    • Zeis T., and Schaeren-Wiemers N. Lame ducks or fierce creatures? The role of oligodendrocytes in multiple sclerosis. J. Mol. Neurosci. 35 (2008) 91-100
    • (2008) J. Mol. Neurosci. , vol.35 , pp. 91-100
    • Zeis, T.1    Schaeren-Wiemers, N.2
  • 48
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system: the toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
    • Bsibsi M., Ravid R., Gveric D., and van Noort J.M. Broad expression of Toll-like receptors in the human central nervous system: the toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J. Neuropathol. Exp. Neurol. 61 (2002) 1013-1021
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    van Noort, J.M.4
  • 49
    • 49349106109 scopus 로고    scopus 로고
    • Preconditioning with cobalt chloride or desferrioxamine protects oligodendrocyte cell line (MO3.13) from tumor necrosis factor-alpha-mediated cell death
    • Yao S.Y., Soutto M., and Sriram S. Preconditioning with cobalt chloride or desferrioxamine protects oligodendrocyte cell line (MO3.13) from tumor necrosis factor-alpha-mediated cell death. J. Neurosci. Res. 86 (2008) 2403-2413
    • (2008) J. Neurosci. Res. , vol.86 , pp. 2403-2413
    • Yao, S.Y.1    Soutto, M.2    Sriram, S.3
  • 50
    • 0141532262 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira S. Toll-like receptor signaling. J. Biol. Chem. 278 (2003) 38105-38108
    • (2003) J. Biol. Chem. , vol.278 , pp. 38105-38108
    • Akira, S.1
  • 51
    • 0032900218 scopus 로고    scopus 로고
    • Cytokine induction of inducible nitric oxide synthase in an oligodendrocyte cell line: role of p38 mitogen-activated protein kinase activation
    • Bhat N.R., Zhang P., and Bhat A.N. Cytokine induction of inducible nitric oxide synthase in an oligodendrocyte cell line: role of p38 mitogen-activated protein kinase activation. J. Neurochem. 72 (1999) 472-478
    • (1999) J. Neurochem. , vol.72 , pp. 472-478
    • Bhat, N.R.1    Zhang, P.2    Bhat, A.N.3
  • 52
    • 20444430445 scopus 로고    scopus 로고
    • Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8-oxoguanine glycosylase to mitochondria
    • Druzhyna N.M., Musiyenko S.I., Wilson G.L., and LeDoux S.P. Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8-oxoguanine glycosylase to mitochondria. J. Biol. Chem. 280 (2005) 21673-21679
    • (2005) J. Biol. Chem. , vol.280 , pp. 21673-21679
    • Druzhyna, N.M.1    Musiyenko, S.I.2    Wilson, G.L.3    LeDoux, S.P.4
  • 53
    • 0035132294 scopus 로고    scopus 로고
    • LPS/IFN-gamma cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10
    • Molina-Holgado E., Vela J.M., Arevalo-Martin A., and Guaza C. LPS/IFN-gamma cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10. Eur. J. Neurosci. 13 (2001) 493-502
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 493-502
    • Molina-Holgado, E.1    Vela, J.M.2    Arevalo-Martin, A.3    Guaza, C.4
  • 54
    • 0033135875 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in cultures enriched for mature oligodendrocytes is due to microglia
    • Hewett J.A., Hewett S.J., Winkler S., and Pfeiffer S.E. Inducible nitric oxide synthase expression in cultures enriched for mature oligodendrocytes is due to microglia. J. Neurosci. Res. 56 (1999) 189-198
    • (1999) J. Neurosci. Res. , vol.56 , pp. 189-198
    • Hewett, J.A.1    Hewett, S.J.2    Winkler, S.3    Pfeiffer, S.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.